Assignee: Dabur Research Foundation

Location: Ghaziabad, IN
No. of patents: 25

Number	Title	Issue Date
7173006	Drug comprising synthetic peptide analogs for the treatment of cancer The present invention relates to a combination of peptides that may be used for treatment of cancer. The peptide combination competes for the binding of specific neuropeptides at the plasma membrane and thereby alters the levels of key intracellular molecules implic...	02/06/2007
7094755	Vasoactive intestinal peptide analogs The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs containing...	08/22/2006
7060678	Peptides comprising furanoid sugar amino acids for the treatment of cancer Anticancer peptides which incorporate furanoid sugar amino acids and compositions made using these peptides are described. Methods for synthesis of the peptides and for preparing the furanoid sugar amino acids are disclosed. The peptides and compositions made using ...	06/13/2006
6989371	Bombesin analogs for treatment of cancer The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the design and synthesis of the novel peptides incorporating α,α-amino aci...	01/24/2006
6949557	Hydroanthracene based compounds as anticancer agents The invention relates to the use of novel anthracene based compounds for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of hy...	09/27/2005
6949513	Polypeptides of covalently linked synthetic bioactive peptide analog(s) for treatment of cancer A polypeptide of the formula (I), Pa-L-Pb-L-Pc-L-Pd. ...	09/27/2005
6828304	Peptides for treatment of cancer This invention relates to novel antiproliferative and anti secrectory peptides that are inhibitory to vasoactive intestinal peptide receptor and are useful in the treatment of cancer. The invention particularly relates to the synthesis of lipid-peptide conjugates co...	12/07/2004
6670345	Betulinic acid derivatives for inhabiting cancer growth and process for the manufacture of betulinic acid The invention relates to the use of betulinic acid derivatives for the inhibition and or prevention of cancer growth. The invention also relates to novel betulinic acid derivatives useful for inhibition of tumor cancer cells and a process for the preparat...	12/30/2003
6632832	Anti-cancer activity of carvedilol and its isomers The present invention provides for pharmaceutical compositions comprising carvedilol for treatment of cancer. More particularly the invention relates to the use of carvedilol for treatment of cancers of the colon, ovary, breast, prostate, pancreas, lung, ...	10/14/2003
6613793	Anticancer activity of imino acid conjugates or methylglyoxal The invention relates to the use of imino acid conjugates of methylglyoxal for the inhibition and/or treatment of cancer. The invention relates more specifically to the use imino acid conjugates of methylglyoxal for inhibition and/or treatment of cancer o...	09/02/2003
6608174	Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy The present invention encompasses radiolabeled peptide analogs of vasoactive intestinal peptide (VIP) labeled with a radionuclide useful for imaging target sites within mammalian living systems. The invention particularly provides radiolabeled VIP derivat...	08/19/2003
6596755	Oral formulation of methylglyoxal and its imino acid conjugates for human use The invention relates to an oral formulation of methylglyoxal and/or its imino acid conjugates for human use and methods for preparing the compositions. Particularly, the invention relates to compositions comprising methylglyoxal and more particularly, im...	07/22/2003
6596692	Substance P analogs for the treatment of cancer The present invention encompasses novel synthetic peptide analogs that are antagonists to Substance P, substance P like peptides and related peptides and are useful for the treatment of cancer. The invention particularly relates to the design and synthesi...	07/22/2003
6492330	Antiangiogenic drugs The invention relates to the use of peptides individually or in combination, for treating and/or preventing angiogenesis. It also relates to the use of peptide analogs or a combination of peptides referred to as MuJ-7 as anticancer drugs in restricting th...	12/10/2002
6489297	Vasoactive intestinal peptide analogs The present invention encompasses novel analogs of vasoactive intestinal peptide (VIP), containing substitutions at appropriately selected amino acids. The invention particularly relates to the design and synthesis of novel biologically active VIP analogs...	12/03/2002
6403816	Betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis The invention relates to novel betulinic acid derivatives having antiangiogenic activity, processes for producing such derivatives and their use for treating tumor associated angiogenesis....	06/11/2002
6395771	Paclitaxel derivatives for the treatment of cancer The invention provides novel paclitaxel derivatives obtained by effecting modifications at C2', C3' and/or C7 positions of paclitaxel, said derivatives being useful in inhibiting the growth of cancer of lung, breast, ovary...	05/28/2002
6316414	Somatostatin analogs for the treatment of cancer The present invention encompasses novel peptides that are agonists to somatostatin and the use of the agonists for treatment of cancer. The invention particularly relates to the design and synthesis of novel analogs of somatostatin incorporating ଱, ...	11/13/2001
6264998	Extracting betulinic acid from Ziziphus jujuba A process for isolating betulinic acid from Ziziphus jujuba is disclosed. The process involves the steps of: a) extracting bark of Ziziphus jujuba in a solvent to obtain an extract containing betulinic acid, b) semi-concentrating the extract containing betulin...	07/24/2001
6228850	Antiangiogenic activity of betulinic acid and its derivatives Use of betulinic acid and/or its derivatives for inhibiting and/or preventing angiogenesis is described. Compositions containing betulinic acid derivatives with or without betulinic acid can be used for these purposed....	05/08/2001
6214814	Use of betulinic acid derivatives for inhibiting cancer growth The invention relates to the use of betulinic acid and its derivatives for the inhibition and/or prevention or cancer growth. The invention also relates to novel betulinic acid derivatives useful for the inhibition of tumor/cancer cells and a process for ...	04/10/2001
6136316	Hepatoprotective compositions and composition for treatment of conditions related to hepatitis B and E infection The invention provides a novel polyherbal composition useful for treating acute Hepatitis E virus infection including acute liver failure due to HEV infection, healthy Hepatitis B virus carriers who develop superadded hepatitis E virus infection, acute he...	10/24/2000
6124482	Process for isolation of 10-deacetyl baccatin-III A novel process for isolation of 10-deacetyl baccatin-III (10-DAB) and also complete separation of paclitaxel present in the primary extract, on a commercial scale from plant extract of Taxus species by solvent crystallization without employing chromatogr...	09/26/2000
6048847	Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this The invention relates to use of betulinic acid and/or its derivatives for treating, inhibiting, and/or preventing tumors or cancer growth more particularly, to treating leukemia, lymphomas, lung, prostate and ovarian cancer. This invention also relates to...	04/11/2000
6002024	Process for the isolation of 14ଲ-hydroxy-10-deacetyl baccatin-III Novel process for isolation of 14ଲ-hydroxy 10-deacetyl baccatin-III (14ଲ-OH-DAB) on a commercial scale from plant extract by solvent crystallization without employing chromatographic separation....	12/14/1999

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Assignee: Dabur Research Foundation