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Vehicular Impact Signaling Device
An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.
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| Number | Title | Issue Date |
| 7959928 | VLP-antigen conjugates and their uses as vaccines The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus-like particle (VLP) of an RNA-bacteriophage and at least one antigen, wherein the VLP is recombinantly pro... | 06/14/2011 |
| 7959924 | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The present invention provides, inter alia, a composition comprising a virus-like particle (VLP) and at least one antigen, wherein said antigen is a GIP pr... | 06/14/2011 |
| 7888098 | Scalable process for protein purification The invention provides a process for the purification recombinantly expressed, self-assembled VLP from the homogenate of a bacterial host, wherein the process can be scaled up to a commercial production scale in a cost effective manner. The process comprises a first... | 02/15/2011 |
| 7785873 | Antigen arrays for treatment of bone disease The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular a RANKL protein, RANKL fragmen... | 08/31/2010 |
| 7767212 | CAT allergen conjugates and uses thereof The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides compositions comprising a virus-like particle (VLP) or a virus particle and at least one antigen, particularly at least one feline a... | 08/03/2010 |
| 7666408 | Angiotensin peptide-carrier conjugates and uses thereof The present invention provides conjugates of peptide derivatives of the mammalian peptide hormones angiotensinogen, angiotensin I and angiotensin II, presented in a repetitive scaffold by coupling the peptide derivatives to a carrier, particularly a virus-like parti... | 02/23/2010 |
| 7517520 | Packaging of immunostimulatory oligonucleotides into virus-like particles: method of preparation and use The invention relates to the finding that virus like particles (VLPs) can be loaded with immunostimulatory substances, in particular with DNA oligonucleotides containing non-methylated C and G (CpGs). Such CpG-VLPs are dramatically more immunogenic than their CpG-fr... | 04/14/2009 |
| 7494656 | Molecular antigen arrays The present invention provides a composition comprising an AP205 virus like particle (VLP) and an antigen. The invention also provides a process for producing an antigen or antigenic determinant bound to AP205 VLP. AP205 VLP bound to an antigen is useful in the prod... | 02/24/2009 |
| 7452541 | Hapten-carrier conjugates and uses thereof The present invention provides compositions comprising a conjugate of a hapten with a carrier in an ordered and repetitive array, and methods of making such compositions. The conjugates and compositions of the invention may comprise a variety of haptens, including h... | 11/18/2008 |
| 7371542 | Gene expression system The present invention relates to nucleic acid molecules and in particular to vectors, comprising at least one gene of interest, at least one scaffold/matrix attached region (S/MAR), at least one origin of replication, and at least one replication initiation factor, ... | 05/13/2008 |
| 7320793 | Molecular antigen array The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for produc... | 01/22/2008 |
| 7279165 | Amyloid β1-6 antigen arrays The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an Aβ1-6 peptide-VLP-composit... | 10/09/2007 |
| 7264810 | Molecular antigen array The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for produc... | 09/04/2007 |
| 7229624 | Ordered molecular presentation of antigens, method of preparation and use The invention provides compositions and processes for the production of ordered and repetitive antigen or antigenic determinant arrays. The compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, the treatme... | 06/12/2007 |
| 7138252 | Molecular antigen arrays The present invention provides a composition comprising an AP205 virus like particle (VLP) and an antigen. The invention also provides a process for producing an antigen or antigenic determinant bound to AP205 VLP. AP205 VLP bound to an antigen is useful in the prod... | 11/21/2006 |
| 7128911 | Antigen arrays for treatment of bone disease The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular a RANKL protein, RANKL fragmen... | 10/31/2006 |
| 7115266 | Angiotensin peptide-carrier conjugates and uses thereof The present invention provides conjugates of peptide derivatives of the mammalian peptide hormones angiotensinogen, angiotensin I and angiotensin II, presented in a repetitive scaffold by coupling the peptide derivatives to a carrier, particularly a virus-like parti... | 10/03/2006 |
| 7094409 | Antigen arrays for treatment of allergic eosinophilic diseases The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein ... | 08/22/2006 |
| 7005275 | Inducible alphaviral gene expression system The present invention provides novel expression vectors which permit tight regulation of gene expression in eucaryotic cells. More specifically, the invention provides DNA vectors comprising nucleotide sequences that are transcribed to form RNA molecules which are t... | 02/28/2006 |
| 6964769 | Molecular antigen array The invention provides compositions and processes for the production of ordered and repetitive antigen or antigenic determinant arrays. The compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, the treatme... | 11/15/2005 |
| 6932971 | Hapten-carrier conjugates and uses thereof The present invention provides compositions comprising a conjugate of a hapten with a carrier in an ordered and repetitive array, and methods of making such compositions. The conjugates and compositions of the invention may comprise a variety of haptens, including h... | 08/23/2005 |
| 6576443 | Replicon based activation of endogenous genes The present invention relates to methods for the modification of genomes of eukaryotic cells to alter the expression of endogenous genes. The invention also relates to recombinant eukaryotic host cells and polypeptides produced by the practice of the disc... | 06/10/2003 |
| 6524792 | Expression cloning processes for the discovery, characterization and isolation of genes encoding polypeptides with a predetermined property The present invention is directed to a method for detection, characterization and isolation of nucleic acids encoding proteins of a desired property, such as a particular cellular localization. The invention further provides for rapid expression of such p... | 02/25/2003 |
| 6197502 | Expression cloning processes for the discovery characterization, and isolation of genes encoding polypeptides with a predetermined property The present invention is directed to a method for detection, characterization and isolation of nucleic acids encoding proteins of a desired property, such as a particular cellular localization. The invention further provides for rapid expression of such p... | 03/06/2001 |
