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| Number | Title | Issue Date |
| 4499073 | Intravenously injectable immune serum globulin A composition is disclosed which comprises a solution in a pharmaceutically acceptable carrier of an immune serum globulin, said solution having an ionic strength and a pH to maintain the monomer content and the actual and latent anticomplement activity o... | 02/12/1985 |
| 4479989 | Flexible container material Film material for use in sterilized medical solution containers such as blood bags or I.V. bags, comprising 30-90% linear low density polyethylene (LLDPE) and 10-70% styrene-ethylene-butylene-styrene (SEBS). The particular LLDPE and SEBS materials are sel... | 10/30/1984 |
| 4477432 | Oral immune globulin There is disclosed an oral pharmaceutical composition for therapeutic use comprising a therapeutically effective amount of orally administerable immune globulin in a pharmaceutically acceptable carrier.... | 10/16/1984 |
| 4455301 | Antihemophilic factor concentrate Novel antihemophilic factor concentrates and process for making the same are disclosed. An aqueous solution of anithemophilic factor proteins is obtained, preferably by solubilizing antihemophilic factor proteins from blood plasma cryoprecipitate in water... | 06/19/1984 |
| 4455300 | Fibronectin compositions Novel compositions containing fibronectin and methods of isolating these compositions and fibronectin itself from blood plasma are disclosed.... | 06/19/1984 |
| 4452893 | Cell growth medium supplement Fraction IV, a discard fraction of the Cohn fractionation scheme, may be used as a supplement in cell growth media if the Fraction IV is rendered substantially free of components within the molecular weight range 2.5×105 -1.0×1010,... | 06/05/1984 |
| 4450104 | Water insoluble gel matrix containing lectin bound to antithrombin A lectin-containing, water-insoluble gel matrix with a glycoprotein reversibly bound thereto can be used for fractionating a polysaccharidic substance capable of being separated into components of differing activity by virtue of differing affinity for the... | 05/22/1984 |
| 4447414 | Carnivore anthelmintics A broad spectrum anthelmintic composition useful for eliminating nematodes and cestodes from carnivores. Composition comprises anthelmintically effective amounts of compounds which act systemically and via direct contact in carnivore gut, the compounds be... | 05/08/1984 |
| 4446126 | Antithrombin-heparin complex and method for its production A complex of antithrombin and high activity heparin is provided for use as a potent anticoagulant for humans. The complex is prepared by reversibly immobilizing it on a lectin-containing, water-insoluble gel matrix and then removing it from the matrix.... | 05/01/1984 |
| 4446314 | Fractionation of heparin A lectin-containing, water-insoluble gel matrix with a glycoprotein reversibly bound thereto can be used for fractionating a polysaccharidic substance capable of being separated into components of differing activity by virtue of differing affinity for the... | 05/01/1984 |
| 4442833 | Casting or splinting package A novel casting or splinting package is disclosed wherein a sheet comprising a textile substrate impregnated or coated with a water-curable resin system is non-sealably confined between a sheet of resilient, non-water-absorptive material and a sheet of fl... | 04/17/1984 |
| 4440679 | Pasteurized therapeutically active protein compositions Compositions containing thermally sensitive, therapeutically active proteins are pasteurized without substantial loss of therapeutic activity by mixing the protein composition with a pasteurization-stabilizing amount of a polyol prior to pasteurization. P... | 04/03/1984 |
| 4435177 | Needle assembly There is disclosed a needle assembly comprising a needle, a needle-retaining portion, a removable needle protector portion, and a resilient member for removing liquid from the surface of the needle which is disposed around the needle rearward of its point... | 03/06/1984 |
| 4416661 | Injection site for fluids Injection site device comprising an elastomeric plug closing a fluid entry port and held in a compression fit by means of an open overcap bonded to the outer surfaces of the entry port.... | 11/22/1983 |
| 4414238 | Liquid elemental diet A ready-to-use liquid elemental diet comprising a nutritionally acceptable combination of carbohydrate, amino acid, and lipid components, the combination having a pH ranging from about 3.0 to 4.4, being non-browning at elevated temperatures, and including... | 11/08/1983 |
| 4412990 | Composition having enhanced opsonic activity There is disclosed a pharmaceutical composition for therapeutic use comprising an immune globulin and fibronectin in amounts sufficient to produce an opsonic activity in the composition that is greater than the additive opsonic activity of the individual ... | 11/01/1983 |
| 4404132 | Blood coagulation promoting product This disclosure pertains to a concentrate for controlling bleeding in hemophilia, free of thrombin, heparin, thromboplastin activity, anticomplement activity, depressor activity, and activated Factor X, and containing coagulation Factors II, VII, IX, and ... | 09/13/1983 |
| 4396608 | Intravenously injectable immune serum globulin A composition is disclosed which comprises a solution in a pharmaceutically acceptable carrier of an immune serum globulin, said solution having an ionic strength and a pH to maintain the monomer content and the actual and latent anticomplement activity o... | 08/02/1983 |
| 4394919 | Closure for container A closure for containers which is inexpensively and easily manufactured and is readily removeable in whole or in part to gain access to contents in the container. The closure comprises a generally flat cap member sealed at its periphery to the mouth of th... | 07/26/1983 |
| 4391801 | Plasma protein fraction substantially free of acetate ions Stable plasma protein fractions (PPF) substantially free of vasodepressant amounts of acetate ions are disclosed. Solutions of the disclosed PPF are suitable for intravenous administration to patients without deleterious vasodepressor effects. Methods are... | 07/05/1983 |
| 4391746 | Blood-coagulation-promoting products and methods of preparing them Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors... | 07/05/1983 |
| 4386068 | Antihemophilic factor concentrate and method for preparation Novel antihemophilic factor concentrates and process for making the same are disclosed. An aqueous solution of antihemophilic factor proteins is obtained, preferably by solubilizing antihemophilic factor proteins from blood plasma cryoprecipitate in water... | 05/31/1983 |
| 4386025 | Method of preparing antithrombin A lectin-containing, water-insoluble gel matrix with a glycoprotein reversibly bound thereto can be used for fractionating a polysaccharidic substance capable of being separated into components of differing activity by virtue of differing affinity for the... | 05/31/1983 |
| 4382679 | Dye leak detection method An improved method for testing the integrity of containers and closures for same is disclosed which is simple, easy to perform, and possesses a high degree of sensitivity. The method comprises immersing a container (whose walls are substantially transpare... | 05/10/1983 |
| 4379087 | Method of preparing alpha-1-proteinase inhibitor A method is disclosed for separating alpha-1-proteinase inhibitor from a blood plasma fraction particularly from the Cohn fractionation scheme. An aqueous solution of the blood plasma fraction is held at a pH of about 6.5-8.5, and a temperature of about 2... | 04/05/1983 |
| 4366384 | Air bubble detector Air bubbles in a transparent intravenous solution conduit are detected, regardless of whether the solution is opaque or clear, by directing a light source at the conduit and detecting light shining through the solution with a first light sensor while dete... | 12/28/1982 |
| 4364861 | Blood-coagulation-promoting products and methods of preparing them Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors... | 12/21/1982 |
| 4361148 | Flexible conduit with releasable sealing means A means for releasable sealing a flexible conduit is disclosed, having particular use in a conduit connecting multiple blood bags. The conduit contains within a portion of itself a flexible strip or tubular insert. This portion of the conduit is positivel... | 11/30/1982 |
| 4361510 | Blood coagulation promoting product The disclosure pertains to a concentrate for controlling bleeding in hemophilia, free of thrombin, heparin, thromboplastin activity, anticomplement activity, depressor activity, and activated Factor X, and containing coagulation Factors II, VII, IX, and X... | 11/30/1982 |
| 4355783 | Flow control device An improvement in a flow control device for permitting fine adjustment of flow rates of fluid in tubing and maintaining established rates of flow. The device includes a clamping member pivotally mounted adjacent a clamping surface and a tubing-engaging su... | 10/26/1982 |
| 4341764 | Method of preparing fibronectin and antihemophilic factor Methods are disclosed for obtaining fibronectin and antihemophilic factor in commercial quantities from blood plasma. In the disclosed methods a blood plasma fraction containing fibronectin and antihemophilic factor is isolated from blood plasma and then ... | 07/27/1982 |
| 4334535 | Conduit device for rapid priming and flow of liquid A unit for rapid priming and flow of liquid through the unit is disclosed. The unit comprises a connector for communicating with liquid in a sealed container, the connector having an exit orifice around which is secured one end of a primer tube. The other... | 06/15/1982 |
| 4328946 | Flow control device An improvement in a flow control device for permitting fine adjustment of flow rates of fluid in tubing and maintaining established rates of flow. The device includes a clamping member pivotally mounted adjacent a clamping surface and a tubing-engaging su... | 05/11/1982 |
| 4315073 | Titration of serum influenza antibody using plaque reduction neutralization test Influenza antibody levels in serum can be measured via plaque reduction neutralization (PRN) technique. Test is more sensitive and specific for measuring anti-infective influenza antibodies than present hemagglutination inhibition (HAI) test and can be us... | 02/09/1982 |
| 4307868 | Flow control device An improvement in a flow control device for permitting fine adjustment of flow rates of fluid in tubing and maintaining established rates of flow. The device includes a clamping member pivotally mounted adjacent a clamping surface and a tubing-engaging su... | 12/29/1981 |
| 4294249 | Swage-molded injection site An injection site is disclosed comprising a self-sealing, puncturable member of resilient material and a housing wherein the puncturable member is compressibly confined by a swage-molded edge on the top of the housing. The injection site may be attached t... | 10/13/1981 |
| 4285968 | Pesticidal concentrate with stabilizing agent Pesticidal concentrate comprising o-isopropoxyphenyl methylcarbamate and an acidifying agent dissolved in a liquid, water soluble, dispersion medium.... | 08/25/1981 |
| 4280497 | Container for platelet storage A plastic bag containing a platelet concentrate is disclosed wherein the viability of platelets remains at a high level even after storage at 22° C. for up to five days. The bag in which the platelet concentrate is stored comprises walls of polyvinyl chl... | 07/28/1981 |
| 4272521 | Purified immune serum globulin Existing and potential prekallikrein activator (PKA) can be removed from an immune serum globulin (ISG) solution using an ion exchange material to remove both existing PKA and a kallikrein-activatable precursor to PKA (Factor XII) found to be present in I... | 06/09/1981 |
| 4265425 | Flow control device An improvement in a flow control device for permitting fine adjustment of flow rates of fluid in tubing and maintaining established rates of flow. The device includes a clamping member pivotally mounted adjacent a clamping surface and a tubing-engaging su... | 05/05/1981 |