Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8129342 | High purity lipopeptides The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromat... | 03/06/2012 |
| 8058238 | High purity lipopeptides The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromat... | 11/15/2011 |
| 8003673 | Daptomycin for the treatment of biofilm and catheter salvage Daptomycin can be used for biofilm treatment (particularly central venous catheter salvage for S. epidermidis infected catheters). Catheter salvage with daptomycin shows rapid cidality, activity against stationary phase bacteria, and penetration and activity ... | 08/23/2011 |
| 7527807 | Compositions and methods for increasing the oral absorption of antimicrobials The present invention provides compositions and methods for increasing absorption of antibacterial agents, particularly third generation cephalosporin antibacterial agents, in oral dosage solid and/or suspension forms. Specifically, the composition is comprised of a... | 05/05/2009 |
| 7408025 | Lipopeptides as antibacterial agents The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel... | 08/05/2008 |
| 7335726 | Lipopeptide stereoisomers, methods for preparing same and useful intermediates The present invention provides daptomycin stereoisomeric compounds, methods and intermediates for preparing daptomycin and daptomycin stereoisomoeric compounds, as well as pharmaceutical compositions of these compounds and methods of using these compositions as anti... | 02/26/2008 |
| 7335725 | Lipopeptides as antibacterial agents The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel... | 02/26/2008 |
| 7262268 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates The present invention provides daptomycin stereoisomeric compounds, methods and intermediates for preparing daptomycin and daptomycin stereoisomoeric compounds, as well as pharmaceutical compositions of these compounds and methods of using these compositions as anti... | 08/28/2007 |
| 7235651 | Genes and proteins involved in the biosynthesis of lipopeptides Genes and proteins involved in the biosynthesis of lipopeptides by microorganisms, in particular the nucleic acids forming the biosynthetic locus for the A54145 lipopeptide from Streptomyces fradiae and the A54145-like lipopeptide from Streptomyces refuine... | 06/26/2007 |
| 6911525 | Lipopeptides as antibacterial agents The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel... | 06/28/2005 |
| 6852689 | Methods for administration of antibiotics The invention provides methods for administering a therapeutically effective amount of daptomycin while minimizing skeletal muscle toxicity. The methods provide daptomycin administration at a dosing interval of 24 hours or greater. This long dosing interval minimize... | 02/08/2005 |
| 6846625 | Method for identifying validated target and assay combination for drug development The invention comprises methods useful within a larger process for identifying compounds and/or designing further compounds with activity to produce a desired phenotype (for example, growth inhibition) in cells whose target cell component is the subject of certain s... | 01/25/2005 |
| 6794490 | Lipopeptides as antibacterial agents The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel... | 09/21/2004 |
| 6784203 | Cytokine production inhibitors A 5,6-dihydro-α-pyrone of formula (I) wherein R is CO2H or CH3 and, when R is CO2H, a pharmaceutically or veterinarily acceptable salt thereof. Processes for producing compounds of formu... | 08/31/2004 |
| 6696412 | High purity lipopeptides, Lipopeptide micelles and processes for preparing same The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interact... | 02/24/2004 |
| 6475726 | Method for identifying validated target and assay combinations for drug development The invention comprises methods useful within a larger process for identifying compounds and/or designing further compounds with activity to produce a desired phenotype (for example, growth inhibition) in cells whose target cell component is the subject o... | 11/05/2002 |
| 6468967 | Methods for administration of antibiotics The invention provides methods for administering a therapeutically effective amount of daptomycin while minimizing skeletal muscle toxicity. The methods provide daptomycin administration at a dosing interval of 24 hours or greater. This long dosing interv... | 10/22/2002 |
| 6436694 | Regulable gene expression in gram-positive bacteria A system has been constructed which is suitable for tetracycline-inducible gene expression in Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. The replicon/host gene expression system is tightly regulated, can be used in complex... | 08/20/2002 |
