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| Number | Title | Issue Date |
| 7207939 | Apparatus and method for analyzing a liquid in a capillary tube of a hematology instrument An apparatus and method for determining the density and fluid-type of a fluid flowing in a capillary tube, the velocity and viscosity of a blood sample flowing in a capillary tube, the erythrocyte sedimentation rate (ESR) of a blood sample after flow has been brough... | 04/24/2007 |
| 7006922 | Stellar icon for data representation and system and method forming the stellar icon A stellar icon for representing multivariate data includes finger members corresponding to constituents of a sample with a length corresponding to an expression of an attribute of the constituent. The finger members are positioned on the base member so that the fing... | 02/28/2006 |
| 6955872 | Dye compositions which provide enhanced differential fluorescence and light scatter characteristics A composition for enhancing differential staining of RNA, DNA and granules in a sample comprising cells contains a first fluorescent dye that can bind specific binding sites and non-specific binding sites in the sample. This first dye emits fluorescence at a first w... | 10/18/2005 |
| 6941005 | Monitoring and control of droplet sorting Methods, systems and apparatus are provided for sorting particles in a stream of a sample in a flow cytometer by producing from a stable sort having desirable sort characteristics multiple images of a portion of the stream; generating from the multiple images an ave... | 09/06/2005 |
| 6922241 | Fiber optic apparatus for detecting light scatter to differentiate blood cells and the like Apparatus for detecting light scattered by a small particle (e.g., a blood cell) irradiated by a light beam comprises one or more photodetectors and a plurality of optical fibers that serve to optically couple the scattered light and the photodetector(s). To enhance... | 07/26/2005 |
| 6894779 | Apparatus for detecting back-scatter in a laser-based blood analysis system A back-scatter detector for detecting light scattered backwardly (i.e., reflected) by an irradiated particle such as a blood cell comprises a plurality of optical fibers. A fiber optic holder having a centrally located opening for passing a light beam used to irradi... | 05/17/2005 |
| 6873725 | Simultaneous measurement and display of 3-D size distributions of particulate materials in suspensions An apparatus and method in which a still image, or still images, are obtained of a plurality of particles suspended in a fluid medium. Each still image is transferred to an image analyzing unit that measures a set of dimensional characteristics per particle for part... | 03/29/2005 |
| 6872541 | Method and compositions for analysis of pentraxin receptors as indicators of disease A kit for assessing the level of pentraxin-binding moieties on particles in a biological sample containing a ligand comprising a pentraxin is useful in a method of assessing pentraxin-binding of particles for use in diagnosis of disease or abnormality. The method in... | 03/29/2005 |
| 6872361 | Dual pad liquid shear valve assembly A shear valve assembly comprises a pair of valve pads having opposing planar surfaces supported for relative sliding engagement. Each valve pad defines a plurality of liquid pathways by which a liquid can be passed from one pad to the other. The planar surface of on... | 03/29/2005 |
| 6869569 | Apparatus for differentiating blood cells using back-scatter Blood cells of interest are readily distinguishable from other blood cells and look-a-like particles found in a blood sample by their back-scatter signature. A preferred method for differentiating platelets in a blood sample is to irradiate the cells and particles, ... | 03/22/2005 |
| 6859276 | Extracted polarization intensity differential scattering for particle characterization A particle sizing method and apparatus of the PIDS type uses randomly polarized radiation to irradiate a particle sample. Portions of the resulting side scattering pattern are decomposed to simultaneously produce, for each decomposed portion, first and second linear... | 02/22/2005 |
| 6798508 | Fiber optic apparatus for detecting light scatter to differentiate blood cells and the like Apparatus for detecting light scattered by a small particle (e.g., a blood cell) irradiated by a light beam comprises one or more photodetectors and a plurality of optical fibers that serve to optically couple the scattered light and the photodetector(s). To enhance... | 09/28/2004 |
| 6778910 | Statistical probability distribution-preserving accumulation of log transformed data A signal processing operator successfully expands the dynamic range of a histogram of digital data, such as that representative of biological cell populations, including human blood cells subjected to flow cytometry processing, without introducing binning artifacts ... | 08/17/2004 |
| 6744245 | Particle count correction method and apparatus A method is disclosed which allows more accurate counting of particles where the sample has significant size variability between particles. The method uses flight time and wait time to obtain a corrected count of particles. ... | 06/01/2004 |
| 6743634 | Method and apparatus for differentiating blood cells using back-scatter Blood cells of interest are readily distinguishable from other blood cells and look-a-like particles found in a blood sample by their back-scatter signature. A preferred method for differentiating platelets in a blood sample is to irradiate the cells and particles, ... | 06/01/2004 |
| 6706526 | Low formaldehyde producing blood diluent A low formaldehyde containing aqueous blood diluent contains an effective amount of ethylenediamine tetraacetic acid, ethylenediamine tetraacetic acid derivative, or combinations thereof; an effective amount of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-i... | 03/16/2004 |
| 6696243 | Method for the analysis of soluble analytes A method of analyzing the concentration of soluble analyte in a sample involves performing a competition assay using a predetermined amount of formed bodies to which are attached at least one analyte, varying known concentrations of an unlabeled ligand th... | 02/24/2004 |
| 6692702 | Apparatus for biological sample preparation and analysis A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cell... | 02/17/2004 |
| 6692968 | Apparatus and method for sample purification and analysis A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber me... | 02/17/2004 |
| 6673618 | Method for measurement of nucleated red blood cells A method for differentiating and enumerating nucleated red blood cells in a blood sample is described. The method includes the steps of lysing red blood cells of a blood sample with a lytic reagent, measuring nucleated blood cells by DC impedance measurem... | 01/06/2004 |
| 6581012 | Automated laboratory software architecture An integrated clinical laboratory software system for testing a specimen. At least one specimen processing module is advantageously provided, each for performing particular predetermined tests on the specimen. Integrated work flow automation programming c... | 06/17/2003 |
| 6579685 | Method and apparatus for screening microscopic cells utilizing light scatter techniques A method for performing screening of one or more cell groups of interest obscured by a cell population such as one or more subsets of interest of a WBC population utilizing at least one light sensing parameter. The cell group of interest is enumerated by ... | 06/17/2003 |
| 6572255 | Apparatus for controllably mixing and delivering diluted solution A physically compact (saline) solution preparation apparatus includes a solution mixing tank coupled to sources of concentrate and diluent. A concentrate transport path is configured to both homogenize and deliver concentrate to the mixing tank, while the... | 06/03/2003 |
| 6573102 | Lytic reagent composition for determination of nucleated blood cells A lytic reagent composition for measuring nucleated blood cells in a blood sample is described. The lytic reagent composition contains a quaternary ammonium surfactant, an ethoxylated phenol, and an ethoxylated alcohol. When mixed with a blood sample, the... | 06/03/2003 |
| 6569682 | Hematology control product with increased closed vial stability An improved blood suspension media for hematological compositions, having particular utility with a red blood cell component for devices using electronic and optical means for blood determinations, and processes for using the suspension media. The suspens... | 05/27/2003 |
| 6551831 | Dyes and methods of detection of nucleic acid in immature red blood cells The dyes of the present invention are useful for many purposes that include markers or tags for detecting the presence of a molecule or compound to which they are bound. The dyes may be either red-excitable or blue-excitable. The dyes of the invention are... | 04/22/2003 |
| 6535836 | Method for the analysis of abnormal particle populations A method for analyzing an abnormal particle population in an experimental sample containing particles involves a particle property distribution index based on an average particle property (e.g., size) distribution curve for multiple normal samples in a pa... | 03/18/2003 |
| 6514772 | Semiconductor nanoparticles for analysis of blood cell populations and methods of making same A semiconductor nanoparticle for use in analysis of biological samples is described. This semiconductor nanoparticle is composed of an aminodextran which is bound to at least one nanoparticle of the formula (X Y)n wherein X is selected from the... | 02/04/2003 |
| 6509192 | Quality control method A method of quality control to diagnose the cause of a malfunction of an instrument. The method uses measurements of the physical property of a sample to diagnose the cause of a malfunction of an instrument. The spatial position of a control product sampl... | 01/21/2003 |
| 6472215 | Method of analyzing nucleated red blood cells in a blood sample A method of analyzing nucleated red blood cells (NRBCs) in a blood sample and further enumerating NRBCs is disclosed. The method includes lysing a first aliquot and a second aliquot of a blood sample separately with a first lysing reagent system and a sec... | 10/29/2002 |
| 6454141 | Non-pressurized dry powder dispensing apparatus An apparatus and a method for dispersing and feeding dry powders without using pressurized air are disclosed. The apparatus comprises a sample holder, a suction probe, a vacuum means and a positional means. The suction probe is positioned above dry powder... | 09/24/2002 |
| 6452372 | Duet jfet rf oscillator-detector for flow cytometer A junction field effect transistor (JFET) RF oscillator-detector circuit generates an RF signal for an apparatus for conducting electrical measurements of particles contained in a carrier fluid passing through an aperture in a cytometer flow cell. The JFE... | 09/17/2002 |
| 6410330 | Method for measurement of nucleated red blood cells A method for differentiating and enumerating nucleated red blood cells in a blood sample is described. The method includes the steps of lysing red blood cells of a blood sample with a lytic reagent, measuring nucleated blood cells by DC impedance measurem... | 06/25/2002 |
| 6387622 | Ligand-aminodextran-marker conjugates and uses thereof Ligand-aminodextran-(phycobiliprotein or tandem dye) conjugates useful for detection of a desired target biological material by providing an enhanced fluorescent signal are described. Also described is a method for a single-measurement quantification of m... | 05/14/2002 |
| 6368864 | Dyes and methods of reticulocyte enumeration A dye compound having the formula I: ##STR1## wherein, n is 0, 1, 2, or 3; R1 is H, alkyl, or an alkoxy group; R2 is CH.sub.2 (CH.sub.2).sub.m OH, wherein m is 0, 1, 2, or 3; X is O, S, or C(CH.sub.3).sub.2 ; R is CH.sub.3, CH(CH.sub.3).sub.2, CH.sub.2 CH... | 04/09/2002 |
| 6363802 | Apparatus for aspirating liquid from a vessel Apparatus for precisely aspirating small volumes of liquid, e.g., a blood sample, contained in a vessel, e.g., a test tube or vial, includes a mechanism for sensing that the tip of an aspirating probe is contacting the bottom of the vessel during the aspi... | 04/02/2002 |
| 6343690 | Specimen carrier for automated transport system and method and apparatus for identifying same A specimen carrier comprises a unitary structure for receiving and retaining a specimen container in an upright orientation. Such unitary structure is defined by a pedestal having upper and lower platforms connected by a stem. Extending upwardly from the ... | 02/05/2002 |
| 6323632 | Solid state RF oscillator-detector for flow cytometer A junction field effect transistor (JFET) RF oscillator-detector circuit generates an RF signal for an apparatus for conducting electrical measurements of particles contained in a carrier fluid passing through an aperture in a cytometer flow cell. The JFE... | 11/27/2001 |
| 6322752 | Method and apparatus for aspirating and dispensing liquids A method and apparatus for aspirating and dispensing precise volumes of liquid, e.g. whole blood, comprises an aspiration probe or needle having an internal volume precisely equal to a desired volume to be dispensed, and a computer-controlled shear valve ... | 11/27/2001 |
| 6318158 | Sample preparation and delivery system employing external sonicator A particulate sample mixing and delivery apparatus externally sonically mixes respective samples of particulate stored in storage containers that are sequentially indexed by a carousel prior to being dispensed into an analyzer reservoir. Each container is... | 11/20/2001 |
