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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Assignee: Cortech, Inc.


Location: Denver, CO
No. of patents: 23

NumberTitleIssue Date
6075120Bradykinin antagonist
A bradykinin antagonist of the formula: (BKAn)(X)(Y) where BKAn is a bradykinin antagonist peptide; Y is a pharmacore; and X is a bridging link chemically joining the BKAn and Y components....
06/13/2000
5891852Serine protease inhibitors-cycloheptane derivatives
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respira...
04/06/1999
5874585Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase....
02/23/1999
5869455Serine protease inhibitors-N-substituted derivatives
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respira...
02/09/1999
5863899Bradykinin antagonists
A bradykinin antagonist of the formula: (BKAn) (X) (Y) where BKAn is a bradykinin antagonist peptide; Y is a Pharmacophore; and X is a bridging link chemically joining the BKAn and Y components....
01/26/1999
5861380Serine protease inhibitors-keto and di-keto containing ring systems
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respira...
01/19/1999
5849863Cytolytic bradykinin antagonists
The present invention provides bradykinin antagonists effective to inhibit cancer cell growth. Also provided are methods of inhibiting lung cancer cell growth by administering a therapeutically effective amount of a dimerized bradykinin antagonist....
12/15/1998
5843900Bradykinin antagonists
The present invention relates to pharmaceutically effective heterodimers comprising a bradykinin antagonist component covalently linked to a mu-opioid agonist component....
12/01/1998
5834431Des-Arg9 -BK antagonists
The present invention provides des-Arg9 bradykinin analogs which are selective B1 receptor antagonists....
11/10/1998
5811241Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
The invention provides a method of synthesizing N-substituted 1,4-piperazines and N-substituted 1,4-piperazinediones. The invention also provides a method for synthesing combinatorial libraries of piperazine derivatives which can be assayed for biological...
09/22/1998
5807829Serine protease inhibitor--tripeptoid analogs
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respira...
09/15/1998
5801148Serine protease inhibitors-proline analogs
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of human neutrophil elastase (HNE) for the treatment of HNE-mediated processes implicated in conditions such as adult respira...
09/01/1998
5750506Bradykinin antagonists with extended hydrophobic side chains
Bradykinin antagonists, particularly Cys6 analogs, which have an extended hydrophobic side chain....
05/12/1998
5700779Bradykinin antagonist peptides incorporating N-substituted glycines
The present invention provides bradykinin type peptides containing N-substituted glycines, particularly bradykinin antagonist peptides useful for the treatment of conditions mediated by bradykinin including pain and inflammation....
12/23/1997
5635593Bradykinin antagonists
A brandykinin antagonist of the formula: X(BKA)n wherein BKA is the peptide chain of a bradykinin antagonist peptide, X is a linking group and n is a whole number greater than 1. The BKA substituents may be the same or different. Monomeric antagonis...
06/03/1997
5618792Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases including human neutrophil elastase, equivalently known as human leukocyte elastase....
04/08/1997
5610140Bradykinin receptor antagonists with neurokinin receptor blocking activity
The present invention provides a heterodimeric compound possessing bradykinin and neurokinin receptor antagonist activities useful in the treatment of asthma and other inflammatory diseases especially those involving the airway or pulmonary system. The pr...
03/11/1997
5416191Bradykinin antagonists
A bradykinin antagonist of the formula X(BKA)n wherein BKA is the peptide chain of a bradykinin antagonist peptide, X is a linking group and n is a whole number greater than 1. The BKA substituents may be the same or different. Monomeric antagonists...
05/16/1995
5314910Ester inhibitors
2-Heteroaromatic alkanoate esters which are useful as inhibitors of human leukocyate or neutrophil elastase....
05/24/1994
5281617N-succinimidyl and N-phthalimidyl esters of 2-phenylalkanoic acid derivatives as inhibitors of human leukocyte elastase
N-succinimidyl and N-phthalimidyl esters of phenylalkanoic acid derivatives which are useful as inhibitors of HLE or HNE....
01/25/1994
5240956Ester inhibitors
2-Heteroaromatic alkanoate esters which are useful as inhibitors of human leukocyate or neutrophil elastase....
08/31/1993
5216022Aromatic esters of phenylenedialkanoates as inhibitors of human neutrophil elastase
Compounds of the formula ##STR1## wherein: R1, R2, R3 and R4, which may be the same or different, are selected from the group consisting of hydrogen, alkyl of 1-6 carbons, cycloalkyl of 3 to 6 carbons, alke...
06/01/1993
5214191Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase
2-Phenylalkanoate esters which are useful as inhibitors of human leukocyte elastase....
05/25/1993
 
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