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Assignee: Cor Therapeutics, Inc.


Location: SouthSanFrancisco, CA
No. of patents: 16

NumberTitleIssue Date
6399627Inhibitors of factor Xa
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders....
06/04/2002
6372475Cloning and characterization of a human adenylyl cyclase
A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described....
04/16/2002
6369063Selective factor Xa inhibitors
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders....
04/09/2002
6297026Nucleic acids encoding the C140 receptor
Nucleic acid molecules encoding the C140 cell surface receptor have been cloned and sequenced. The availability of C140 receptor DNA permits the recombinant production of the C140 receptor which can be produced on the surface of a cell, including an oocyt...
10/02/2001
6228854Selective factor Xa inhibitors
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders....
05/08/2001
6194557Nucleic acid molecules encoding Bap-1 proteins
The present invention provides the amino acid and nucleotide sequence of a protein that binds to 댣 integrins, ଱IIb and Src kinase and is involved in integrin mediated signaling. Based on this disclosure, the present invention provides methods...
02/27/2001
6194435Lactams as selective factor Xa inhibitors
Novel lactams, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds of Formula I below: ##STR1## are useful in vitro or in vivo for preventing or treating coagulation disorders....
02/27/2001
6133256Selective factor Xa inhibitors
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders....
10/17/2000
6083688Platelet glycoprotein V gene and uses
This invention relates to the glycoprotein v gene. Specifically, this invention discloses the sequence and structure of the glycoprotein v gene and the amino acid sequence of the glycoprotein v polypeptide. In addition, the evolutionary relationship of th...
07/04/2000
6005089Platelet glycoprotein V gene and uses
This invention relates to the glycoprotein v gene. Specifically, this invention discloses the sequence and structure of the glycoprotein v gene and the amino acid sequence of the glycoprotein v polypeptide. In addition, the evolutionary relationship of th...
12/21/1999
5843897Platelet aggregation inhibitors
An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samp...
12/01/1998
5795910Method and compositions for inhibiting protein kinases
A method for selectively inhibiting a kinase is disclosed, which comprises contacting a composition containing a kinase with a molecule of the formula ##STR1## wherein R1 is H, lower alkyl, or lower alkanoyl; R2 is H, lower ...
08/18/1998
5728726Method and compositions for inhibiting protein kinases
A method for selectively inhibiting a kinase is disclosed, which comprises contacting a composition containing a kinase with a molecule of the formula ##STR1## wherein R1 is H, lower alkyl, or lower alkanoyl; R2 is H, lower ...
03/17/1998
5686572Domains of extracellular region of human platelet derived growth factor receptor polypeptides
Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both ce...
11/11/1997
5342830Antithrombosis agents
Platelet antiadhesives (PAA) which are useful as antithrombotics are obtainable from snake venoms which have been identified using an assay which measures the ability of the venom to inhibit ristocetin- or botrocetin-induced agglutination of platelets in ...
08/30/1994
5278144Antithrombosis agents
Analogs of Factor Xa (Factor Xai) which are inactive as proteases in the prothrombinase reaction are useful in treatment of diseases characterized by thrombosis. These antithrombotic agents can be conveniently prepared using recombinant techniques....
01/11/1994
 
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