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...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 8093229 | Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors Alkynyl pyrrolo [2,3-d] pyrimidines of Formula I are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compound... | 01/10/2012 |
| 7579462 | Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins Efficient chemical processes for preparing high yields, purities, and different polymorphic forms of 17-allyl amino geldanamycin (17-AAG) and other ansamycins are described and claimed. ... | 08/25/2009 |
| 7553979 | HSP90-inhibiting zearalanol compounds and methods of producing and using same Zearalanol compounds are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various disorders. Methods of synthesis and use of such compounds are also described and claimed. | 06/30/2009 |
| 7544672 | Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such com... | 06/09/2009 |
| 7465718 | Ansamycins having improved pharmacological and biological properties Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and othe... | 12/16/2008 |
| 7241890 | Purine analogs having HSP90-inhibiting activity Novel purine compounds of Formula I. and tautomers, pharmaceutically acceptable salts, and prodrugs thereof, wherein X is S, S(O), or S(O)2; and O is selected from alkyl, cycloalkyl, arylalkyl, aryl, h... | 07/10/2007 |
| 7148228 | Pyrazolopyrimidines and related analogs as HSP90-inhibitors A compound represented by Formula I, or a polymorph, ester, tautomer, enantiomer, pharmaceutically acceptable salt or prodrug thereof: wherein: R1 is halogen, —OR1... | 12/12/2006 |
| 7138402 | Pyrrolopyrimidines and related analogs as HSP90-inhibitors The present invention provides compounds represented by Formula I. R0 is selected from hydrogen, halogen, lower alkyl, —SR8, —OR8, —CN, and —NHR8, R1 is halogen, or lower alkyl; R2 is —NHR | 11/21/2006 |
| 7138401 | 2-aminopurine analogs having HSP90-inhibiting activity 2-Aminopurine analogs are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of su... | 11/21/2006 |
| 7129244 | Triazolopyrimidines and related analogs as HSP90-inhibitors A compound represented by Formula I, or a polymorph, ester, tautomer, enantiomer, diastereomer, pharmaceutically acceptable salt or prodrug thereof, Wherein R1 is halogen, —OR11, —SR | 10/31/2006 |
