Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 6974679 | Support with collagen base for tissue engineering and manufacture of biomaterials The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising ... | 12/13/2005 |
| 6790454 | Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained A composite product is disclosed as a collagen support comprising at least one porous collagen layer covered on at least one side with an essentially compact collagen membrane consisting either of a collagen film prepared by drying a collagen gel, preferably in air ... | 09/14/2004 |
| 6703490 | Amphiphilic complexes, method for their preparation and compositions containing them Cosmetic and pharmaceutical compositions comprising amphiphilic or hydrolipidic complexes of plant proteins modified with fatty chains are presented. The modified proteins are obtained from the reaction carried out at a temperature between ambient tempera... | 03/09/2004 |
| 6660280 | Collagen product containing collagen of marine origin with a low odor and preferably with improved mechanical properties, and its use in the form of cosmetic or pharmaceutical compositions or products The invention relates to a collagen product containing collagen of marine origin with a low odor. The collagen product includes one or more collagens or derivatives thereof, including hydrolyzates, with a low odor, at least part of the collagen or the der... | 12/09/2003 |
| 6548170 | Treated water-insoluble solid particles, preparation and use The present invention relates to water-insoluble solid particles, especially pigments, which characteristically are coated with at least one layer of at least one product resulting from the reaction between at least one molecule capable of becoming hydrat... | 04/15/2003 |
| 6541023 | Use of collagen of aquatic origin for the production of supports for tissue engineering, and supports and biomaterials obtained Use of collagen of aquatic origin for the production of supports for tissue engineering is disclosed. The collagen may be obtained from fish skin, preferably in its native form. Novel tissue engineering supports with a low risk of contamination are produc... | 04/01/2003 |
| 6524595 | Cyclodextrins preferentially substituted on their primary face by acid or amine functions Non-hydroxyalkylated cyclodextrins are disclosed wherein at least one primary alcohol function (CH2 OH) is substituted, the --OH portion being replaced by a substituent with formula --O--CO--R or --NR1 R2, where: R, R... | 02/25/2003 |
| 6471973 | Flavonoide esters and their use notably in cosmetics The invention relates to a flavonoid ester. This flavonoid ester results from the reaction product of at least one flavonoid selected from the group consisting of a flavonoid with a ketone group in the 4-position, a salt, ester or ether of such a flavonoi... | 10/29/2002 |
| 6303150 | Method for producing nanocapsules with crosslinked protein-based walls nanocapsules thereby obtained and cosmetic, pharmaceutical and food compositions using same A method for producing nanocapsules with cross-linked protein-based walls, comprising preparing emulsions of said proteins and crosslinking these with a crosslinking agent having reactive groups which react with the reactive groups of said proteins, parti... | 10/16/2001 |
| 6235294 | Flavonoide esters and their use notably in cosmetics The invention relates to a flavonoid ester. This flavonoid ester results from the reaction product of at least one flavonoid selected from the group consisting of a flavonoid with a ketone group in the 4-position, a salt, ester or ether of such a flavonoi... | 05/22/2001 |
| 6039961 | Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation The invention relates to new lipophilic hydroxylated acids wherein said lipophilic hydroxylated acid comprises a hydrophobic hydrocarbon chain having from 7 to 30 carbon atoms grafted onto the hydroxyl functional group and/or the acid functional group of ... | 03/21/2000 |
| 5989596 | Compositions comprising a depigmenting agent consisting of sulfites and metabisulfites and plant extracts for use in inhibiting melanogenesis or for depigmenting The invention relates to the use of sulfite, including metabisulfite, as melanogenesis-inhibiting or depigmenting agent. The invention enables preparing melanogenesis-inhibiting or depigmenting cosmetic compositions and optionally advantageously pharmaceu... | 11/23/1999 |
| 5912016 | Particles of crosslinked plant proteins and the process for their preparation The invention relates to particles. These particles comprise, at least on the surface, a wall formed of plant proteins crosslinked particularly by means of interfacial crosslinking between the plant proteins and an acylating polyfunctional crosslinking ag... | 06/15/1999 |
| 5904921 | Stabilized compositions of superoxide dismutase obtained from germinated plant seeds Germinated plant seeds are disclosed as a source of superoxide dismutase (SOD). The SOD is stabilized to temperatures of at least 45° C. when combined in a stabilizing composition comprising a peroxidase, a peroxidase cofactor, and a hydrophilic substanc... | 05/18/1999 |
| 5869069 | Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation The invention relates to new lipophilic hydroxylated acids wherein said lipophilic hydroxylated acid comprises a hydrophobic hydrocarbon chain having from 7 to 30 carbon atoms grafted onto the hydroxyl functional group and/or the acid functional group of ... | 02/09/1999 |
| 5691060 | Utilization of a transacylation reaction between an esterified polysaccharide and a polyaminated or polyhydroxylated substance for fabricating microparticles, microparticles thus obtained, methods and compositions containing them The invention relates to microparticles, particularly microcapsules and their fabrication method. Said microparticles, and particularly said microcapsules, are characterized in that they have a wall made of the product obtained from the reaction between a... | 11/25/1997 |
| 5672301 | Method for fabricating microparticles in emulsion by modification of the chemical composition of the dispersed phase after emulsification The method for producing microparticles is characterized in that it comprises the following steps: preparation of an emulsion of a solution of a substance or a mixture of substances in a dispersing liquid wherein said substance or said mixture are substan... | 09/30/1997 |
| 5658593 | Injectable compositions containing collagen microcapsules A collagen-based composition including microcapsules of atelocollagen or of a mixture of atelocollagen and a polysaccharide, particularly glycosaminoglycan, suspended in a viscous biocompatible carrier solution. Together, the microcapsules and the viscous... | 08/19/1997 |
| 5648208 | Use of a collagen as solid binding substrate for a ligand capable of reacting specifically with an element to be detected in a biological medium, reactant and implementation The invention relates to the use of collagen as solid binding substrate for a sensor called ligand or refining agent, capable of reacting specifically with an element to be detected in a biological medium, to form a specific complex. Preferably, the solid... | 07/15/1997 |
| 5635609 | Particles prepared by transacylation reaction between an esterified polysaccharide and a polyamine, methods of preparation therefor and compositions containing same Particles, preparation methods therefor, and compositions containing same. The particles include at least one esterified polysaccharide and at least one polyamine, as well as at least one gellable polysaccharide when neither the esterified polysaccharide ... | 06/03/1997 |
| 5525359 | Microcapsules having a combined atelocollagen/polyholoside wall coagulated by a divalent cation and method for manufacturing these microcapsules and cosmetic or pharmaceutical or food compositions containing them The invention relates to microcapsules having a combined atelocollagen/polyholoside coagulated wall as well as to a method for producing them. According to the invention, the microcapsules are characterized in that they include a combined atelocollagen/po... | 06/11/1996 |
| 5422111 | Polyose/fatty acid complex product with a high fatty acid content, use as an emulsifier or moisturizer and emulsifying or moisturizing composition in which it is present The invention relates to a polyose/fatty acid complex product. This complex product is the reaction product of at least one polyose with at least one fatty acid, in particular in the form of a halide or the anhydride. The fatty acid can be saturated or un... | 06/06/1995 |
| 5420248 | Unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, collagen and biomaterial thereby obtained The present invention relates to the use of unpigmented skin from flat fish as novel industrial source of collagen. As unpigmented skin, the ventral skin is used in particular, from sole, dab, turbot, brill. Native acid-soluble collagen is advantageously ... | 05/30/1995 |
| 5395620 | Biodegradable microcapsules having walls composed of crosslinked atelocollagen and polyholoside The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules. According to the invention, the microcapsules comprise... | 03/07/1995 |
| 5331092 | Process of preparation of collagen containing in major proportion insoluble collagen and collagen having high mechanical resistance and thermal stability obtained thereby A process of preparation of collagen containing in major proportion insoluble collagen is disclosed, including rinsing and washing the collagenic tissue, acidifying the ground material pH value 1 to 4 to get a collagenic paste which is diluted in a diluti... | 07/19/1994 |
| 5244672 | Composition containing liposomes stabilized by a stabilizing support based on atelocollagen and glycosaminoglycans The invention relates to a composition containing liposomes, stabilized by a stabilizing support comprising a mixture of atelocollagen and glycosaminoglycans in a relative proportion preferably ranging between 18 and 25% by weight of the atelocollagen. Th... | 09/14/1993 |
