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| Number | Title | Issue Date |
| 8184129 | Techniques for 3-D elastic spatial registration of multiple modes of measuring a body Techniques for registration of multiple measurement modes of a body include receiving first and second data from different modes. Each includes measured values with coordinate values. For two mechanically aligned modes, any non-rigid registration is performed. For s... | 05/22/2012 |
| 8107703 | Quantitative real-time 4D stress test analysis Stress test analysis is facilitated through the acquired and manipulated use of a sequence of volumetric data regarding the heart (and may particularly comprise the left ventricle) for the assessment of the health state of the heart. Several provided and illustrated... | 01/31/2012 |
| 8106005 | Modulating apoptosis The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-κB activity. The modulators may be used, for example, in the treatment of NF-κB-mediated diseases, conditions, and injuries. ... | 01/31/2012 |
| 8008260 | Methods of protecting against apoptosis using lipopeptides The use of lipopeptides as inducers of NF-κB for the protection of mammals from the effects of apoptosis is described. ... | 08/30/2011 |
| 8007812 | Flagellin related polypeptides and uses thereof The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described. ... | 08/30/2011 |
| 8002816 | Prosthesis for implantation in aorta and method of using same Prosthesis for implantation in the ascending aorta comprising a tubular body made of biocompatible graft material, a cuff at the proximal portion of the tubular body for biasing pressure onto a sino-tubular junction and that is configured to conform to the junction.... | 08/23/2011 |
| 7979107 | System and method for differentiation of normal and malignant in vivo liver tissues A method for differentiating malignant in vivo liver tissues from normal in vivo liver tissues of a living subject includes the steps of: (a) illuminating a first area and a second area of in vivo liver tissues of the living subject with a first excitation light, (b... | 07/12/2011 |
| 7972374 | Securing rods and modular graft systems Modular graft systems with conjoinable grafts comprising graft material with the system comprising a first and second graft prosthesis with mating ends, securing rods attached to one of the mating ends comprising at least one spike that juts from the securing rod. T... | 07/05/2011 |
| 7638485 | Modulating apoptosis The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-κB activity. The modulators may be used, for example, in the treatment of NF-κB-mediated diseases, conditions, and injuries. ... | 12/29/2009 |
| 7359554 | System and method for identifying a vascular border A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular u... | 04/15/2008 |
| 7280710 | Architecture for real-time 3D image registration A system architecture is disclosed that facilitates rapid execution of 3D registration or alignment algorithms. A first image module (e.g., RAM) is included to store data corresponding to images to be registered. A processor coupled to the first storage module acces... | 10/09/2007 |
| 7183256 | TIMP3 as VEGF inhibitor Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF recptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VE... | 02/27/2007 |
| 7182736 | Apparatus and method for assessing loads on adjacent bones An apparatus (10) that utilizes microelectromechanical systems (MEMS) technology to provide an in vivo assessment of loads on adjacent bones (24 and 26) comprises a body (34) for insertion between the adjacent bones. At least one sensor (... | 02/27/2007 |
| 7175597 | Non-invasive tissue characterization system and method One embodiment of the present system and method is directed to the identification of tissues within a vascular object by analyzing ultrasound data collected from the vascular object by non-invasive scans. By identifying and characterizing types of tissue from ultras... | 02/13/2007 |
| 7087079 | Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve A stentless bioprosthetic valve includes at least one piece of biocompatible material comprising a bi-leaflet conduit. The conduit has a distal end and a proximal end that defines a first annulus for suturing to the valve annulus of a heart. The conduit further incl... | 08/08/2006 |
| 7048856 | Ultrafiltration membrane, device, bioartificial organ, and methods The present invention relates to ultrafiltration. In particular, the present invention provides a compact ultrafiltration device and methods for generating an ultrafiltrate, both of which can be used for a variety of applications, including, but not limited to filte... | 05/23/2006 |
| 7014653 | Furcated endovascular prosthesis An endovascular prosthesis (10) includes a first end (16) a furcated second end (18), and an anchoring means (20). The first end has a longitudinally extending central lumen (32) and means (40) for laterally supporting the f... | 03/21/2006 |
| 7004925 | Apparatus and method for auto-retroperfusion of a coronary vein An apparatus for automatically retroperfusing a coronary vein includes an intraluminal cannula having a main body portion extending between a proximal end portion and a distal end portion. The proximal end portion is for connecting to an artery outside of the perica... | 02/28/2006 |
| 7004926 | Apparatus and method for auto-retroperfusion of a coronary vein An apparatus for automatically retroperfusing a coronary vein includes an intraluminal cannula having a main body portion extending between a proximal end portion and a distal end portion. The proximal end portion is for connecting to an artery outside of the perica... | 02/28/2006 |
| 6994672 | Apparatus and method for measuring intraocular pressure An apparatus (176) for measuring intraocular pressure (IOP) comprises an applanation tonometer (180) having a distal end that is movable toward the eye and a disposable module (188) positioned at the distal end. The module (188) includes ... | 02/07/2006 |
| 6802806 | Apparatus for use with an inflow cannula of ventricular assist device An apparatus (10) for use with an inflow cannula (12) of a ventricular assist device (VAD) (14). The cannula (12) has a first part (30) for connecting with a ventricle (22) of a heart (24) and a second part (32... | 10/12/2004 |
| 6790372 | Microneedle array module and method of fabricating the same A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an ... | 09/14/2004 |
| 6755813 | Apparatus and method for performing thrombolysis An apparatus (10) for delivery of an infusate into a body lumen (12) to perform thrombolysis includes a catheter (24) having an infusion section (40) defined by a plurality of infusion ports (42) for delivering the infusate. The in... | 06/29/2004 |
| 6749568 | Intraocular pressure measurement system including a sensor mounted in a contact lens An apparatus for measuring intraocular pressure (IOP) comprises a contact lens including an inner surface contoured to a surface portion of an eye and a sensor disposed in the contact lens. The sensor comprises a contact surface for making contact with the surface p... | 06/15/2004 |
| 6641606 | Delivery system and method for deploying an endovascular prosthesis The present invention relates to an apparatus (300) for delivering an endovascular prosthesis within a blood vessel. The apparatus (300) includes a sheath (302) having a first end (310), a second end (308), an inner lumen (316) for receiving an endovascul... | 11/04/2003 |
| 6623470 | Method and apparatus for controlling blood volume and hydration and for indicating resuscitation status of a patient using peripheral venous pressure as a hemodynamic parameter An apparatus for controlling fluid volume in a patient includes a fluid source (16) and a fluid conduit (32, 34, 36) for carrying fluid from the fluid source to the patient (12). A controllable infusion pump (30) pumps fluid from the fluid source to a per... | 09/23/2003 |
| 6494835 | Method and apparatus for intravascular brachytherapy treatment planning A method for providing intravascular brachytherapy includes the step of positioning a radiation source within a target area to be radiation and orienting the attenuator found on the catheter. Once the attenuator or shield is properly oriented, a reference... | 12/17/2002 |
| 6488683 | Method and apparatus for correcting spinal deformity An apparatus (10) for correcting spinal deformity comprises at least one anchor (20) for implantation into a vertebral body (90). The anchor (20) includes a platform (24) having a first surface (38) for facing the vertebral body (90). The platform (24) in... | 12/03/2002 |
| 6468309 | Method and apparatus for stabilizing adjacent bones An apparatus (10) is provided for implantation into an adjacent pair of vertebral bodies (12 and 14) having first and second surfaces (17 and 19) that oppose each other. The apparatus (10), when implanted, is attached to the adjacent pair of vertebral bod... | 10/22/2002 |
| 6460207 | Anti-SIDS pediatric headrest The invention provides a headrest assembly for supporting the head of a child comprising a cradle mounted in a support base. The cradle may be pivotally mounted within the support base with spring loaded joints. The cradle has a first contoured section fo... | 10/08/2002 |
| 6447449 | System for measuring intraocular pressure of an eye and a MEM sensor for use therewith A tonometer sensor for disposition in proximity to a portion of a surface of eye comprises a substrate including a contact surface for making contact with the surface portion of the eye. The contact surface includes an outer non-compliant region and in in... | 09/10/2002 |
| 6432042 | Intubation system The fiberscope (referred to as an "endoscopic stylet" by the inventor) has a largely semi-rigid insertion cord which permits a user to pre-form the endoscopic stylet to follow the anticipated contours of the airway leading to the trachea and to insure tha... | 08/13/2002 |
| 6423019 | Cranial remodeling headpiece A cranial remodeling orthosis (10) for inducing directed growth and remodeling of an irregularly shaped skull (12). The orthosis (10) comprises a headpiece (14) having an outer wall (18) and an inner wall (16), the inner wall (16) being shaped to receive ... | 07/23/2002 |
| 6315751 | Cardiopulmonary bypass system using vacuum assisted venous drainage A cardiopulmonary by-pass system having a vacuum assisted venous drainage system including a hard-shelled venous reservoir which is closed to atmosphere. The reservoir having a blood inlet for supplying blood removed under negative pressure during operati... | 11/13/2001 |
| 6127176 | Mutant cell lines unresponsive to interleukin 1 Mutant cell lines which have lost their ability to respond to IL-1 are provided. In one embodiment, the mutant cell line lacks or is essentially free of IL-1 receptor associate kinase (IRAK), an IL-1 signaling pathway component. The present invention also... | 10/03/2000 |
| 5972678 | Animal 2-5A dependent RNases Isolated 2-5A-dependent RNases, an interferon-induced enzyme which is activated by 5'-phosphorylated, 2',5'-linked oligoadenylates (2-5A) and implicated in both the molecular mechanisms of interferon action and in the fundamental control of RNA stability ... | 10/26/1999 |
| 5971933 | Method and apparatus to correct for electric field non-uniformity in conductance catheter volumetry A method of determining cardiac volume including the steps of positioning a catheter in a blood-filled chamber of a patient's heart. The catheter comprises an elongated body having a distal end, a proximal end, a plurality of spaced electrodes arrayed on ... | 10/26/1999 |
| 5882312 | Method and apparatus to correct for electric current leakage in conductance volumetry A method of determining cardiac volume including the steps of positioning a catheter output including the steps of positioning a catheter in a blood-filled chamber of a patient's heart. The catheter comprises an elongated body having a distal end, a proxi... | 03/16/1999 |
| 5877019 | Animal 2-5A-dependent RNases and encoding sequences therefor 2-5A-dependent RNase, an endoribonuclease that requires 5'-phosphorylated 2',5'-linked oligoadenylates (2-5A), functions in the molecular mechanism of interferon action. Recombinant, 2-5A-dependent RNase was expressed to high levels (at least 10% of the s... | 03/02/1999 |
| 5866787 | Transgenic plants co-expressing a functional human 2-5A system Novel transgenic plants having the ability to express a functional 2-5A system, i.e., a 2-5A synthetase which produces 5'-phosphorylated, 2',5'-linked oligoadenylates (2-5A) in response to double stranded RNA (dsRNA), and a 2-5A-dependent (RNase L), are d... | 02/02/1999 |
