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Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.

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Assignee: Children's Hospital Research Foundation


Location: Cincinnati, OH
No. of patents: 6

NumberTitleIssue Date
6872406Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems
The present invention comprises a method for delivering pharmaceutical agents within and/or through the dermal and mucosal membranes, utilizing a fusogenic protein. The fusogenic protein is associated with a phospholipid membrane, such as a liposome. The liposome co...
03/29/2005
6849257Lipid hydrolysis therapy for atherosclerosis and related diseases
The present invention comprises a method to diminish and/or eliminate atherosclerotic plaques, in mammals, through direct and indirect treatment of these plaques, in situ, using suitable substances which are capable of lipid removal, primarily through hydrolysis, ei...
02/01/2005
6812340Inhibition of bone tumor formation using antisense cDNA therapy
As described herein, the present invention comprises a method for using tubedown-1 (tbdn-1) antisense reagents as gene therapy agents for the treatment of bone tumors and Ewing's sarcoma family of tumors. Antisense-based reagents, such as tbdn-1 antisense construct ...
11/02/2004
6773627Cubic liquid crystalline compositions and methods for their preparation
Cubic liquid crystalline gel precursors, bulk cubic liquid crystalline gels, and dispersions of cubic liquid crystalline gel particles, and methods for their preparation, are disclosed. The precursors, gels, and dispersions can be used as skin penetration enhancers....
08/10/2004
6696415Treatment of ocular neovascularization and related diseases
Tubedown-1 (tbdn-1), a protein associated with acetyltransferase activity has been characterized and its cDNA isolated. Tbdn-1 regulates endothelial differentiation through protein acetylation, DNA-binding or by interacting with and/or acetylating other p...
02/24/2004
6120528Nipple assembly with endoscope
A device for allowing visual examination of the swallowing of fluids by an infant which includes a nipple mounted housing, a feeding tube for feeding fluid into the nipple, openings in the nipple to allow the fluid to pass or be sucked therethrough, a fur...
09/19/2000
 
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