Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 8058018 | Use of VEGF-D in the diagnosis of lymphangioleiomyomatosis (LAM) disease Described herein are methods of diagnosing lymphangioleiomyomatosis (LAM) that permits differentiating LAM from another lung disorder. Methods of treatment are also provided. ... | 11/15/2011 |
| 8048913 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 11/01/2011 |
| 8030003 | Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3 Eotaxin-3, as a marker for eosinophilic esophagitis and methods of assessing, mitigating, and monitoring eosinophilic esophagitis by altering eotaxin-3 and/or CCR3 function, are disclosed. ... | 10/04/2011 |
| 8026221 | Method, composition and kit for antigenic binding of norwalk-like viruses A method for detecting a Norwalk-Like Virus (NLV) in a biological sample, comprising the steps of: obtaining a biological sample suspected of containing a NLV; contacting the biological sample with at least one human histo-blood group antigen to allow formation of a... | 09/27/2011 |
| 8021403 | Spinal staple system A spinal correction system for the correction or arrest of scoliosis or spinal deformity in immature spines includes a bridge member, a pair of spaced apart legs extending substantially perpendicularly therefrom, and a fastener retaining portion extending substantia... | 09/20/2011 |
| 7977110 | Method for distinguishing between kidney dysfunctions A method for distinguishing between kidney dysfunctions in a mammal, including pre-renal azotemia, an acute renal injury that may progress to acute renal failure, and chronic kidney disease, using a urinary or circulating NGAL assay result that is compared to a pred... | 07/12/2011 |
| 7977098 | Antigenic binding patterns of norovirus to human histo-blood group antigens The invention provides a compound which competitively inhibits the binding of a norovirus with a native blood antigen of a human host, as well as a kit for determining whether an individual has been infected by a norovirus. Also provided is a method for determining ... | 07/12/2011 |
| 7960573 | Method for enantioselective hydrogenation of chromenes A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a c... | 06/14/2011 |
| 7960432 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 06/14/2011 |
| 7959935 | Simulated vernix compositions for skin cleansing and other applications A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains, in one embodiment, hydrated synthetic cells in a lipid matrix to provide properties which are substantially si... | 06/14/2011 |
| 7951532 | Method of screening a midkine modulating agent This invention relates to the discovery that midkine modulates pulmonary vasculature development and smooth muscle cell development. Modulation of midkine activity thus alters pulmonary vasculature development and smooth muscle cell development. The invention provid... | 05/31/2011 |
| 7919240 | Altered gene expression profiles in stable versus acute childhood asthma Differences in gene expression in control and asthma patients to profile, differentiate, evaluate, etc. patients with exacerbated asthma and stable asthma. ... | 04/05/2011 |
| 7915384 | Chimeric peptides for the regulation of GTPases Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are pa... | 03/29/2011 |
| 7896841 | Injection device for administering a vaccine An injection device that self-administers a painless vaccine injections. The injection device (10) can be secured to the patient's skin via a separable base portion (12) of the housing of the device, which can be separated from the device when removing... | 03/01/2011 |
| 7893041 | Oligosaccharide compositions and use thereof in the treatment of infection Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described. ... | 02/22/2011 |
| 7847088 | Classification and diagnosis of the molecular basis of cholestasis The methods and compositions of the invention find use in the clinical diagnosis of cholestasis related syndromes, particularly PFIC types 1, 2, and 3; BRIC types 1 and 2; Alagille syndrome, and alpha1-antitrypsin deficiency. The compositions of the invention includ... | 12/07/2010 |
| 7879547 | Method of detecting the presence of asthma or allergies in a patient Several genes are upregulated in the lung of asthma or allergy sufferers. Many of the genes up-regulated in asthma are involved in arginine metabolism in the lung. Moreover, a set of 291 signature genes was found that can be used to indicate a patient's predilection... | 02/01/2011 |
| 7871785 | Use of secretor, Lewis and sialyl antigen levels in clinical samples as predictors of risk for disease An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a ... | 01/18/2011 |
| 7857976 | Hemofiltration system and method based on monitored patient parameters, supervisory control of hemofiltration, and adaptive control of pumps for hemofiltration A multipurpose hemofiltration system and method are disclosed for the removal of fluid and/or soluble waste from the blood of a patient. The system continuously monitors the flow rates of drained fluid, blood, and infusate. When necessary, the pumping rates of the i... | 12/28/2010 |
| 7826982 | Method of identifying inhibitors using a 3-D structure of RAC-1 GTPASE The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity... | 11/02/2010 |
| 7811776 | Use of VEGF-D in the diagnosis of lymphangioleiomyomatosis (LAM) disease Described herein are methods of diagnosing lymphangioleiomyomatosis (LAM) that permits differentiating LAM from another lung disorder. Methods of treatment are also provided. ... | 10/12/2010 |
| 7807188 | Simulated vernix compositions for skin cleansing and other applications A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains hydrated synthetic cells in a lipid matrix to provide rheological properties which are substantially similar to... | 10/05/2010 |
| 7785463 | Extracorporeal renal replacement modeling system A system, program product and method continuously optimize an ultrafiltration rate during an extracorporeal renal replacement process by modeling physiological and actual rate data. The system maps the sensed, physiological data to a mathematical model to assess the... | 08/31/2010 |
| 7709210 | Diagnosis and prevention of fetal heart disease The present invention relates to a method for assessing the likelihood of the presence or formation of fetal heart disease (such as HLHS) in a fetus. In this methodology, the mother, either before or during pregnancy, is tested for the presence of anti-strep antibod... | 05/04/2010 |
| 7696160 | Compositions useful for and methods of modulating angiogenesis Compositions and methods for treating subjects with disorders characterized by aberrant vascular endothelial cell growth are provided. The compositions comprise agents that are combinations of a Wnt pathway stimulator component and a Tie2 pathway repressor component... | 04/13/2010 |
| 7695971 | Use of non-absorbable fat in determining dietary fat absorption The use of sucrose polyester containing behenate fatty acid chains as a non-absorbable fat marker to determine total dietary fat absorption by the digestive tract of a subject. A test food for use in measuring fat absorption contains a non-absorbable fat and a dieta... | 04/13/2010 |
| 7670314 | Injection device for administering a vaccine A manually-powered injection device that self-administers a painless injection. The injection device provides a method for substantially painless injections of vaccine and other medication into a patient that does not require the use of an anesthetic, that does not ... | 03/02/2010 |
| 7662578 | Method and kit for the early detection of impaired renal status A method and kit for identifying the presence of an early biomarker of impaired renal status following a renal event in a mammalian subject. The method typically comprises (a) providing a body fluid sample obtained from a mammalian subject following a renal event; a... | 02/16/2010 |
| 7641158 | Intravenous stand A portable intravenous stand comprising: (a) a base including a plurality of wheels; (b) a plurality of vertical supports extending from the base; (c) a plurality of cross-members mounted to the plurality of vertical supports to maintain the vertical supports in rel... | 01/05/2010 |
| 7637891 | Method and device for painless injection of medication A device for painlessly injecting medications, and a method for providing a substantially painless injection of medication into a patient that does not require the use of an anesthetic, that does not require the medical personnel to spend a substantial amount of tim... | 12/29/2009 |
| 7582738 | Diagnostic assay for Wiskott-Aldrich syndrome and genetically related disorders The methods and compositions of the invention find use in the clinical diagnosis of primary immunodeficiencies, particularly Wiskott-Aldrich related syndromes. The compositions of the invention include isolated nucleic acid molecules and oligonucleotide pairs suitab... | 09/01/2009 |
| 7528267 | Method for enantioselective hydrogenation of chromenes A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a c... | 05/05/2009 |
| 7517890 | GTPase inhibitors and methods of use The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity... | 04/14/2009 |
| 7488573 | In vivo angiogenesis assay A method for evaluating in vivo a test substance for angiogenesis modulation activity, including the steps of providing a rodent pup having a pupillary membrane system in a first eye, injecting transcorneally proximate to the pupillary membrane a test substance; and... | 02/10/2009 |
| 7481830 | Spinal correction system A spinal correction system for the correction or arrest of scoliosis or spinal deformity in immature spines includes a bridge member, a pair of spaced apart barbed legs extending substantially perpendicularly therefrom, and a fastener retaining portion extending sub... | 01/27/2009 |
| 7417026 | Mobilization of hematopoietic cells Improved methods and pharmaceutical compositions are provided herein for mobilizing hematopoietic progenitor cells from bone marrow into peripheral blood, comprising the administration of an effective amount of an inhibitor of GTPases, such as Rac1 and Rac2 alone or... | 08/26/2008 |
| 7396855 | Compositions and products containing S-equol, and methods for their making A composition for use in making commercial food and skin products comprising S-equol or mixtures, including both a non-racemic mixture and a racemic mixture, of S-equol and R-equol. The composition can be used to make articles of commerce such as food supplements, p... | 07/08/2008 |
| 7311918 | Rotavirus subunit vaccine The present invention is directed to the generation and use of recombinant rotavirus fusion proteins as immunogens to produce a protective immune response from immunized individuals. In one embodiment, the present invention contemplates a recombinant rotavirus fusio... | 12/25/2007 |
| 7240676 | Tracheotomy valve unit A tracheotomy valve unit for use with a tracheotomy tube inserted into a patient's trachea comprises a first end for connection to the tracheotomy tube, a second end comprising a valve unit inlet, a first valve that permits airflow to the tube when the patient inhal... | 07/10/2007 |
| 7235523 | Methods for the treatment of hepatic disorders The present invention relates to the prevention and treatment of injury and diseases to the liver, biliary tract, bile ducts, gall bladder and related hepatobiliary system. Specifically, the present invention relates to methods for decreasing the action of the RON r... | 06/26/2007 |
