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Assignee: Centre National de la Recherche Scientifique


Location: Paris Cedex, FR
No. of patents: 69

1    
NumberTitleIssue Date
8158135Imine based liquid crystals for the controlled release of bioactive materials
The present invention relates to a delivery system based on a film of an imine forming liquid crystalline phase, mixed with at least with one biologically active substance, to which a constant or variable electric field can be applied. The delivery system can be use...
04/17/2012
8138758Method of controlling a magnetoresistive device using an electric field pulse
A method of operating a magnetoresistive device is described. The device comprises a ferromagnetic region configured to exhibit magnetic anisotropy and to allow magnetisation thereof to be switched between at least first and second orientations and a gate capacitive...
03/20/2012
8124578Use of dynamic mixtures for a controlled release of fragrances
The present invention relates to a delivery system in the form of a dynamic mixture obtained by reacting together, in the presence of water, at least one hydrazine derivative with at least one perfuming, flavoring, insect repellent or attractant, bactericide or fung...
02/28/2012
8119119Non-integrative and non-replicative lentivirus, preparation and uses thereof
The invention concerns a non-integrative and non-replicative recombinant lentivirus as well as its uses, in particular for preparing a composition for transferring genes in vitro, ex vivo or in vivo. The invention is useful for transferring genes in any mammal organ...
02/21/2012
8110701Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Process for the preparation of compounds of formula (IV): wherein R1, R2, R3 and R4, which may be identical or different, each represent a hydrogen atom, a linear or branched (C
02/07/2012
7981436Hydrogels for the controlled release of bioactive materials
The present invention relates to the formation of hydrogels based on guanosine hydrazide derivatives in the presence of cations. The hydrogels can be used as a carrier/delivery system for biologically active substances such as flavors, fragrances, insect attractants...
07/19/2011
7918789Longitudinally-steerable structure and endoscope comprising said structure
The invention relates to a longitudinally-steerable structure, comprising essentially longitudinal actuators made from shape memory alloy, Peltier effect elements with N and P doping and electrical control device. The above is characterized in that the actuators are...
04/05/2011
7888357Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
A novel class of pyridazine compositions and related methods of use. ...
02/15/2011
7885767Method, an installation, and a computer program for estimating the initial size of a population of nucleic acids, in particular by PCR
In order to estimate the size of an initial population of nucleic acids in a sample of interest, in particular by PCR, the following steps are performed: a) providing a model of the effectiveness (En) of the PCR, the mod...
02/08/2011
7868517Lamb wave resonator
A Lamb wave resonator includes a piezoelectric layer, and a first electrode against a first face of the piezoelectric layer. The first electrode includes fingers and a contact arm, with each finger including a first side in contact with the contact arm and two other...
01/11/2011
7713779Photoactive nanocomposite and method for the production thereof
The invention concerns a photoactive nanocomposite (3) comprising at least one donor-acceptor couple of semiconductor elements. One of the elements is made of doped nanowires (7) with sp3 structure, and the other of the elements is an organic compound ...
05/11/2010
7713759Method for producing an imaging device
The invention relates to a method for making an imagery device comprising at least one matrix of pixels made of a photon detecting semiconducting material (43), deposited on a substrate in which electronic devices are integrated and with metallic surfaces (
05/11/2010
7656748Method of determining impulse responses from a medium in relation to the transmission of waves between different points
The invention relates to a method of determining impulse responses from a medium (2) in relation to the transmission of waves between different points (T1-TN). The inventive method consists in: transmitting waves in the medium by generating, at each po...
02/02/2010
7633356Tunable-inductance thin-layered superconductor components, method for the production thereof and devices including said components
In the field of thin-layered superconductors, particularly those having tunable or adjustable characteristics, a method for the production of such components is provided, in addition to devices including such components. In such a device, is a stack of thin layers a...
12/15/2009
7629663MSM type photodetection device with resonant cavity comprising a mirror with a network of metallic electrodes
This invention relates to an MSM type photo-detection device designed to detect incident light and comprising reflecting means (2) superposed on a support (1), to form a first mirror for a Fabry-Pérot type resonant cavity, a layer of material (3
12/08/2009
7585456Manufacturing process for thin films made of metal/ceramic composite
The invention concerns a method for making thin films in metal/ceramic composite, characterized in that it consists in: a) preparing a suspension (S) in an organic solvent from a substantially homogeneous mixture of ceramic reinforcements of metal particles, a binde...
09/08/2009
7544775Systems for expressing toxic proteins, vectors and method of producing toxic proteins
The present invention relates to a system for expressing toxic proteins, to an expression vector comprising this system, to a prokaryotic cell transformed with this system, and also to a method for synthesizing a toxic protein using this expression system. The expre...
06/09/2009
7514231Anti-aurora-A monoclonal antibody, method for obtaining same and uses thereof for diagnosing and treating cancers
The invention concerns a monoclonal antibody directed against mammalian aurora-A kinase, the method for obtaining same, as we ll as its uses in cancer diagnosis and prognosis, and in pharmaceutical compositions for cancer treatment. ...
04/07/2009
7507529Oligonucleotides originating from sequences coding for the surface component of PTLV envelope proteins and their uses
The invention relates to the use of oligonucleotides from the nucleotide sequences coding for the amino-terminal region of the surface component (SU) of envelope proteins of PTLV viruses in order to perform methods of detecting every PTLV strain or PTLV-related viru...
03/24/2009
7476386Mixed lipopeptide micelles for inducing an immune response
The invention concerns mixed micelles or micro-aggregates for inducing an immune response containing at least a first lipopeptide comprising a CTL epitope and at least a first lipid motif; and a second lipopeptide comprising at least an auxiliary T epitope and at le...
01/13/2009
7465355Method and device for producting monocrystals
A device for manufacturing a single-crystal solid phase by solidification of a liquid phase, comprising: a crucible capable of containing the solid phase and the liquid phase, the liquid phase being in contact with the crucible and the solid phase being separated fr...
12/16/2008
7452845Mesoporous organic-inorganic hybrid materials for separating gases
The invention concerns a method for preparing organic-inorganic hybrid materials with controlled porosity and functionality comprising hydrolysis and condensation polymerization of a compound of formula (I): Z-R1—Si(OR)(OR′)(OR″), with an alkaline o...
11/18/2008
7439030Preparing membrane receptors from extracellular baculoviruses
The present invention describes a method for producing membrane receptors based on a baculovirus/insect cell system. The invention further includes the receptors produced by the method described herein, a model for studying the properties of these membrane receptors...
10/21/2008
7341718Neuronal gene transfer of adenovirus and herpes virus vectors
The present invention is related to compositions and methods for the delivery of nucleic acids to neurons in a mammal, and uses thereof. The present invention specifically discloses the use of compounds that cause synaptic nerve sprouting to increase neuron retrogra...
03/11/2008
7314928Process for manufacturing morpholino-nucleotides, and use thereof for the analysis of and labelling of nucleic acid sequences
The invention relates to the use of morpholino-nucleosides of formula: in which R1 represents a nucleic base and R2 represents a group corresponding to one of the following formulae:
01/01/2008
7315467Hybrid memory cell for spin-polarized electron current induced switching and writing/reading process using such memory cell
The present invention relates to a magnetoresistive hybrid memory cell comprising a first stacked structure comprising a magnetic tunnel junction including first and second magnetic regions stacked in a parallel, overlying relationship separated by a layer of non-ma...
01/01/2008
7306766Biochip type device
An improved biochip type device comprising a substrate (10) including an intermediate non-absorbent multilayer mirror (12) covered by a layer (14) of high refractive index material having chromophore elements (16) fixed thereon, the layer...
12/11/2007
7298643MRAM element
A magnetoresistive memory element including a trapped magnetic region and a free magnetic region separated by a barrier layer. The free magnetic region comprises a stacking of at least two antiferromagnetically-coupled ferromagnetic layers, a layer magnetic moment v...
11/20/2007
7279334Methods for inducing targeted stimulation of meiotic recombination and kits for performing said methods
The Invention pertains to methods, kits, molecules and cells to increase the rate or recombination and/or target recombination in dividing cells. In a particular aspect, the invention concerns methods and kits to induce targeted meiotic recombination. ...
10/09/2007
7279325Method for identifying antagonist compounds of the estrogen-related receptor 3 (ERR3) by using the x-ray structural coordinates of the ligand binding domain
The present invention relates to the identification of novel biologically active compounds having an agonist or an antagonist effect on the transcriptional-activating activity of the Estrogen-Related Receptor 3 (ERR3). ...
10/09/2007
7252004Imaging method and device employing sherar waves
An imaging method for observing the propagation of a shear wave simultaneously at a multitude of points in a diffusing viscoelastic medium. The shear wave is caused to be generated by firing at least one focused ultrasound compression wave into the viscoelastic medi...
08/07/2007
7235532Angiogenic agents and their uses
The present invention relates to the use of a compound of formula I: in which, A1 is the radical corresponding to D- or L-Ser, A2 is the radical cor...
06/26/2007
7199219Polypeptides derived from vitamin D nuclear receptor, and their uses in particular for screening vitamin D analogues
Polypeptides derived from vitamin D nuclear receptor, which nuclear receptor comprises a ligand-binding domain, or LBD, which contains a flexible insertion domain. The polypeptides are charactarised in that the LBD flexible insertion domain is modified by substituti...
04/03/2007
7196792Liquid crystal based polarimetric system, a process for the calibration of this polarimetric system, and a polarimetric measurement process
A liquid crystal based polarimetric system, a process for the calibration of this polarimetric system, and a polarimetric measurement process intended for measuring the representative parameters of a sample in which the polarimetric system contains an excitation sec...
03/27/2007
7173714Apparatus for parallel detection of the behaviour of mechanical micro-oscillators
The invention concerns an apparatus for parallel detection of the behaviour of mechanical micro-oscillators interacting with the sample (21). The amplitude and the phase of resonance of micro-oscillators (12) are measured with optical means. The invent...
02/06/2007
7157498Diamines having a CaSR modulating activity
The invention concerns diamines of general formula (I), wherein: A represents a group A1 or A2 of general formula (II); B represents a group B1 or B2 of general formula (III); X represents a SO2, CH2, C═O or COO; YZ represents a gr...
01/02/2007
7135311Means for detecting and treating pathologies linked to FGFR3
The invention relates to a method for detecting carcinomas in a biological sample, comprising identifying FGFR3 mutations. ...
11/14/2006
7132222Magnetic etching process, especially for magnetic or magnetooptic recording
Process for writing on a material, in which said material is irradiated by means of a beam of light ions, such as for example He+ ions, said beam of light ions having an energy of the order of or less than a hundred keV, wherein this material comprises a ...
11/07/2006
7112555Use of glycuronic polysaccharides and oligosaccharides as phytosanitary products and/or fertiliser
This invention concerns the use of compounds selected among 1,4β-D-glucuronans, and/or glycuronic polysaccharides derived from polymers of formula (I), and whereof the number of saccharide units is less than about 30, and/or esters and/or ethers correspondin...
09/26/2006
7105083Activated carbons and method for obtaining same from a partly mesophase and partly mesogenic pitch
A method for obtaining activated carbons from a partly mesophased and partly mesogenic pitch containing less than about 40% of the a resins, more than about 40% of type β resins and between about 5 and 30% of type γ resins by activating the pitch preceded by its o...
09/12/2006
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