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| Number | Title | Issue Date |
| 8183355 | Method for the synthesis of oligonucleotide derivatives Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a “click chemistry” reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide,... | 05/22/2012 |
| 8163762 | Purine derivatives having, in particular, anti-proliferative properties, and their biological uses This invention provides 2-, 6, and 9-substituted purine derivatives, particularly 2(1-R hydroxymethylpropylamino)-6-benzylamino-9-isopropyl purine, having, in particular, antiproliferative properties, and suitable for use as pharmaceutical compositions and herbicida... | 04/24/2012 |
| 8157050 | Device for reducing noise generated by an aircraft jet engine with curve ducts A jet engine, including a wall surrounding a first gas flow ejected from a downstream end of the wall along a longitudinal axis, a second flow of gas running outside the wall in a direction of ejection of the first gas flow, at least one duct arranged on the periphe... | 04/17/2012 |
| 8155267 | Device for the X-ray analysis of a specimen, comprising an energy/angle-filtering diffraction analyser system A device for X-ray analysis of a sample (1), including: a generation system for the generation of an X-ray beam to irradiate an analysis zone of the sample, said analysis zone defining a analysis mean plane, and the X-ray beam being emitted along a direction ... | 04/10/2012 |
| 8148676 | Use of ionic matrices for maldi mass spectrometry analysis of tissue sections The invention concerns improved methods for studying peptides/proteins expression in a tissue section or for determining at least one compound, in particular a protein, expression map in a tissue section, using ionic MALDI matrices. ... | 04/03/2012 |
| 8138112 | Controlled distribution of active sites in ziegler-natta catalyst systems The present invention provides a method for improving and controlling the activity of Ziegler-Natta catalyst systems. ... | 03/20/2012 |
| 8132756 | Device with plane jets for reducing the noise generated by an aircraft engine An aircraft engine having a longitudinal axis, including a wall surrounding a gas stream that is ejected at a downstream end of the wall along the longitudinal axis, wherein a plurality of conduits distributed at the periphery of the downstream end of the wall are e... | 03/13/2012 |
| 8110591 | 2-aminoaryloxazole compounds as tyrosine kinase inhibitors The present invention relates to novel compounds selected from 2-aminoaryloxazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases ... | 02/07/2012 |
| 8102328 | Method and device for the transmission of waves Method for focusing an electromagnetic or acoustic wave on a point near which one or more diffusers are placed, comprising a learning step in which the pulsed responses hij(t) between the focus point and each antenna of the network are determined. Waves c... | 01/24/2012 |
| 8097590 | α-MSH-antagonist dipeptide conjugates The invention relates to a dipeptide conjugate having general formula I, AA2-AA1-NH2, wherein A represent the radical corresponding to a monocarboxylic acid with general formula II, HOOC—R, in which: R represents a linear or branched aliphatic radical a... | 01/17/2012 |
| 8080524 | Agent for slowing hair loss and/or stimulating hair growth The cosmetic use of at least one compound of formula (I) wherein: A1 is the radical corresponding to D- or L-Ser; A2 is the radical corresponding to D- or L-Asp or Glu; A3 is the radical corresponding to D- or L-Lys, Arg or Orn; A | 12/20/2011 |
| 8063047 | Pyridazine compounds and methods The invention relates to novel chemical compounds of Formula I compositions and methods of using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions com... | 11/22/2011 |
| 8062859 | Method for screening anticancer substances, set or kit for implementing said method A method for screening anticancer substances comprising the following steps: a) obtaining a culture of tumour cells which do not express E-cadherin on their cell membrane; b) bringing the cells obtained at step a) into contact with a candid... | 11/22/2011 |
| 8017581 | MSH-agonist tripeptide conjugates The invention relates to a tripeptide conjugate having general formula I, A-AA1-AA2-AA3-NH2, wherein A represents the radical corresponding to a monocarboxylic acid with general formula II, HOOC—R, in which: R represents a linear or branched aliphatic r... | 09/13/2011 |
| 7999072 | Mutated netrin-4, fragments thereof and their use as medicines Described is use of a netrin selected among netrin-4, mutated netrin-4, netrin-1, netrin G1 or netrin-3, or one of their fragments or a nucleotide sequence encoding one of the netrins or one of the fragments, or an anti-idiotypic antibody of one of the netrins or of... | 08/16/2011 |
| 7993923 | Peptide fractions promoting growth and synthesis of desired product(S) into cell and/or tissue culture The invention relates to preparing and/or supplementing a cell or tissue culture medium. In particular, said invention relates to a serum-free and/or protein-free cell culture medium comprising peptide fractions isolated from rapeseeds, in particular rapeseeds cakes... | 08/09/2011 |
| 7989975 | Apparatus for converting wave energy into electric power The invention concerns an apparatus for converting wave energy into electric power, comprising a closed floating element (1) and a mass forming element (2), the mass forming element (2) being arranged inside the floating element (1) and m... | 08/02/2011 |
| 7960578 | Method for the synthesis of peptides without solvent The disclosure relates to a method for the synthesis of a compound of the formula (I) in which: n is an integer higher than or equal to 1; Rb and each Rn are independently a hydrogen atom, a C1-C6 arylalkyl group or a C1-C6 | 06/14/2011 |
| 7958775 | Triboacoustic probe The invention relates to a sensor for the quantitative measurement of the feel of a surface, comprising a prehensile envelope, a hollow contact body for bringing into contact with the surface on a sensing zone, first acoustic detection elements to detect noises emit... | 06/14/2011 |
| 7939007 | Ceramics based on lanthanum-doped barium titanate, method of preparation and uses The present invention relates to a method of preparing ceramics based on lanthanum-doped barium titanate, which comprises the following steps: (a) flash sintering of lanthanum-doped barium titanate powders; and (b) heat treatment of the material thus obtained, in an... | 05/10/2011 |
| 7932160 | Planar oxidation method for producing a localised buried insulator The invention relates to a method of producing a semiconductor device, comprising the following steps consisting in: forming first, second and third semiconductor layers (1, 2, 3), whereby the first and second layers (1, 3) contain a smaller concentrat... | 04/26/2011 |
| 7894018 | Method for producing a liquid crystal material having a broadened light reflection band The invention relates to a method of producing a liquid crystal material that can be addressed by an electric field. The inventive method is characterised in that it comprises the following steps consisting in: forming a liquid crystal mixture having a helical struc... | 02/22/2011 |
| 7892838 | Method for the in vivo modification of the synthesis activity of a metabolite by means of the modification of a gene the activity of which is not the original activity The invention relates to a method for altering a protein X such as to modify the characteristics thereof by a) obtaining the mutants X* of the sequence coding for protein X, by means of aleatory mutagenesis, b) transformation of cells with a phenotype [P-] with vect... | 02/22/2011 |
| 7889764 | Method for the synchronization of data, such as distributed data, taking account of clock drifts and inaccuracies The present invention relates to a method for creating a correspondence between the local time of a first machine (B), having a first clock (HB), and that of a second machine (A), having a second clock (HA). The invention also relates to... | 02/15/2011 |
| 7887892 | Method of producing a liquid crystal material that reflects more than 50% of non-polarised incident light The invention relates to a method of producing a liquid crystal material. The inventive method is characterised in that it comprises the following steps consisting in: applying a first treatment to a liquid crystal mixture having a helical structure comprising a fir... | 02/15/2011 |
| 7880021 | Compounds and kits for the detection and the quantification of cell apoptosis 3-hydroxyflavone derivatives are useful in the detection and the quantification of cell apoptosis. Such derivatives are also useful as fluorescent probes in studying lipid asymmetry of cell plasma membrane and in detecting apopoptic cells. The derivatives can be use... | 02/01/2011 |
| 7879999 | Method for the synthesis of exocyclic derivatives of cycloalkyl-hydrazines and exocyclic derivatives of heterocycloalkyl-hydrazines The invention relates to a method for the synthesis of exocyclic derivatives of cycloalkyl-hydrazines and exocyclic derivatives of heterocycloalkyl-hydrazines The invention is characterised in that the method comprises a step consisting in demixing a solution contai... | 02/01/2011 |
| 7868506 | Flux-switching dual excitation electrical machine Flux-switching electrical machines. In particular, a flux-switching electrical machine having a stator and a rotor. The stator has permanent magnets, armature windings and excitation windings, and the rotor has no winding or permanent magnet but includes a plurality... | 01/11/2011 |
| 7863413 | Peptide protein translation inhibitor and the use thereof for protein translation control A peptide protein translation inhibitor has a size greater than 250 amino acids and it includes an amino acid sequence which is at least for 85% identical to an amino acid sequence SEQ ID No 1. It also relates to a fusion polypeptide which specifically inhibits an i... | 01/04/2011 |
| 7855785 | Fluorescence detection device This invention relates to a fluorescence detection device comprising a support means (101) for supporting a sample (111), a sample excitation means so that a fluorescence is emitted by the sample (111) and a detection means for detecting said fl... | 12/21/2010 |
| 7821818 | Magnetoresistive tunnel junction magnetic device and its application to MRAM The magnetic device comprises a magnetic device comprising a magnetoresistive tunnel junction (100), itself comprising: a reference magnetic layer (120) having magnetization in a direction that is fixed; a storage magnetic layer (110) having mag... | 10/26/2010 |
| 7820831 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds The invention relates to compounds having the general formula (I), the method of preparation thereof and the use thereof in organic radical synthesis. The invention also relates to compounds having the formula (II), the method of preparation thereof and a method for... | 10/26/2010 |
| 7820422 | Efficient production of oligosaccharides using metabolically engineered microorganisms The present invention relates to the enzymatic synthesis of oligosaccharides, particularly, sialylated oligosaccharides comprising the carbohydrate moeities of the gangliosides GM3, GD3, and GT3. ... | 10/26/2010 |
| 7816520 | 5,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents The invention relates to 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein identical or different R1, R2, R3 and R4 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy... | 10/19/2010 |
| 7815732 | Continuous method for partially crystallising a solution and a device for carrying out said method The invention relates to a device for the partial crystallization of a phase in a solution, comprising at least one pump for circulation of the solution in a circuit of a heat exchanger formed from at least one tube in contact with a cooling circuit, characterized i... | 10/19/2010 |
| 7806493 | Robot for large-format, three dimensional digital printing on a fixed surface and printing method involving at least one such robot The invention relates to a robot for large-format, three-dimensional printing on a fixed surface, using five powered spindles. The inventive robot comprises an inkjet printing block, means for moving and orienting said printing assembly along several axes, at least ... | 10/05/2010 |
| 7795031 | Use of a nucleic acid/PEI complex The invention concerns the use of a nucleic acid/cationic polymer complex, preferably polyethyleneimine (PEI) for preparing a composition for intraventricular stereotactic screening of stem cells of the brain for preparing a medicine for treating neurodegenerative a... | 09/14/2010 |
| 7785577 | Peptides or peptidic conjugate derivatives of MSH and the use thereof for cosmetically fighting against canities The invention relates to a peptide of formula W-DPhe-Arg-Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a monocarboxylic acid of general formula HOOC—R (III), wherein R is an linear or branched possibly s... | 08/31/2010 |
| 7782914 | Device and method for high-energy particle pulse generation A device for generating a high-energy particle pulse is provided which comprises a laser system producing laser pulses with pulse length shorter than 100 fs (femtoseconds), and capable to be focused to peak intensities greater than 10A18 W/cmA2, preferred greater th... | 08/24/2010 |
| 7781174 | Proliferation markers in clinical practice and their use for cancer prognosis or diagnosis The invention relates to a method for assessing the proliferative state of cells in a human or non human biological sample, comprising using Chromatin Assembly Factor-1 (CAF-1 in short) subunits as proliferation markers. Application for cancer prognosis or di... | 08/24/2010 |
