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Assignee: CellGate, Inc.


Location: Redwood City, CA
No. of patents: 7

NumberTitleIssue Date
7312244Polyamine analog-amino acid conjugates useful as anticancer agents
Conjugates in which polyamine analogs are conjugated to an amino acid are provided, as well as compositions comprising these conjugates. Methods of using these conjugates as anticancer treatments are also provided. ...
12/25/2007
7279502Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions...
10/09/2007
7253207Quinones as disease therapies
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided. ...
08/07/2007
7229961Compositions and methods for enhancing drug delivery across and into ocular tissues
This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including into and across ocular tissues and the like. The compositions and methods are also useful for delivery across endothelial tissues, ...
06/12/2007
7186825Conformationally restricted polyamine analogs as disease therapies
Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of d...
03/06/2007
7026347Porphyrin-polyamine conjugates for cancer therapy
Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conju...
04/11/2006
6982351Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearin...
01/03/2006
 
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