Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 8183342 | Method of treating chemotherapy-induced thrombocytopenia A method of treating chemotherapy-induced thrombocytopenia includes administering to a subject undergoing chemotherapy a therapeutically effective amount of a Bax-inhibiting peptide. ... | 05/22/2012 |
| 8165685 | System and method for therapeutic neuromuscular electrical stimulation A system for neuromuscular electrical stimulation therapy includes one or more sensors for sensing the position or the muscle contractions of a body part, such as an arm, hand, finger, leg, etc.; a stimulator in communication with the sensor or sensors; and two or m... | 04/24/2012 |
| 8158373 | Method of detecting cancer and evaluating cancer prognosis A method of detecting cancer in a subject is provided. One step of the method includes obtaining a bodily sample from the subject. Next, the level of pro-prion protein (pro-PrP) in the bodily sample is detected. The level of pro-PrP in the bodily sample is then comp... | 04/17/2012 |
| 8154092 | Silicon carbide MEMS structures and methods of forming the same MEMS structures that include silicon carbide micromechanical components, as well as methods of forming and using the same, are provided. The silicon carbide micromechanical components may be integrated on the same structure with electronic components that control or... | 04/10/2012 |
| 8153280 | Composition comprising silicon carbide A method of depositing a ceramic film, particularly a silicon carbide film, on a substrate is disclosed in which the residual stress, residual stress gradient, and resistivity are controlled. Also disclosed are substrates having a deposited film with these controlle... | 04/10/2012 |
| 8144744 | Co-extruded multilayer polymers films for all-polymer lasers A polymer film laser is provided that comprises a plurality of extruded polymer layers. The plurality of extruded polymer layers comprises a plurality of alternating dielectric layers of a first polymer material having a first refractive index and a second polymer m... | 03/27/2012 |
| 8137991 | Methods of reducing angiogenesis of age-related macular degeneration (AMD) or choroidal neovascularization by an anti-carboxyetheylpyrrole (CFP) antibody The present invention pertains to methods of inhibiting angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of oxidative peptide modifi... | 03/20/2012 |
| 8124749 | Targeted cell death The present invention provides compositions and methods for studying neuropathy. The compositions and methods provided herein are particularly useful for screening agents of therapeutic and/or diagnostic potential. ... | 02/28/2012 |
| 8124097 | Hybrid and chimeric polypeptides that regulate activation of complement A hybrid complement-regulating protein comprises a first functional unit of a first complement regulatory protein having complement regulating properties, a first spacer sequence of at least about 200 amino acids encoding a polypeptide that does not exhibit compleme... | 02/28/2012 |
| 8114847 | Selective inhibitors of translesion DNA replication An agent for inhibiting translesion DNA replication comprises a non-natural adenine ribose analog represented by those as set forth in FIG. 1. ... | 02/14/2012 |
| 8078264 | Intra-operative molecular imaging A system for imaging an abnormal cell and or diseased tissue after topical application of a near infrared protease-specific probe is disclosed. The system includes a protease-specific near infrared (NIRF) imaging probe, means for topically administering the protease... | 12/13/2011 |
| 8076088 | Method of detecting human β-defensins A method of detecting β-defensin in a bodily sample from a subject includes reducing the electrostatic interaction between β-defensin and negatively charged moieties in the bodily sample prior to detecting the β-defensin with an antibody or epitope binding fragme... | 12/13/2011 |
| 8073230 | Systems and methods for generating images for identifying diseases Systems and methods for generating images for identifying diseases are provided. In one embodiment, a method comprises receiving a first digital radiography (DR) image of at least a portion of a body of a patient, receiving a second DR image of the at least a portio... | 12/06/2011 |
| 8060208 | Action potential conduction prevention An example method for selectively and reversibly preventing the conduction of action potentials in a targeted nerve region is presented. The method includes generating an electrical waveform having two phases and selectively depolarizing a nerve membrane using the e... | 11/15/2011 |
| 8059907 | Constant variance filter Systems and methods associated with a constant variance filter are described. One system embodiment includes a memory to store a spatially dependent filtered data set having a first degree of homogeneity. The system embodiment may also include a filter logic to prod... | 11/15/2011 |
| 8049500 | Dynamically selectively configuring wireless transmitter associated with MRI detector coil Systems, methods, and other embodiments associated with dynamically selectively configuring wireless transmitters associated with MRI detector coils are described. One example apparatus includes a detector coil to receive an NMR signal. The apparatus includes a dyna... | 11/01/2011 |
| 8049499 | Controlling multi-channel transmitter effects on specific absorption rate Systems, methods, and other embodiments associated with controlling the specific absorption rate (SAR) in a patient associated with a conductor are described. The conductor may be, for example, a wire associated with a pacemaker, a wire associated with a neurostimul... | 11/01/2011 |
| RE42887 | Silicon carbide and other films and method of deposition A method of depositing a ceramic film, particularly a silicon carbide film, on a substrate is disclosed in which the residual stress, residual stress gradient, and resistivity are controlled. Also disclosed are substrates having a deposited film with these controlle... | 11/01/2011 |
| 8046047 | Extended-coverage imaging coil Extended-coverage magnetic resonance imaging coils with optimized homogeneity in longitudinal sensitivity are described. One exemplary coil includes four elements, where two of the elements are opposed-solenoid imaging elements and two of the elements are single loo... | 10/25/2011 |
| 8034779 | Inhibitors of BCL-2 A purified polypeptide includes an amino acid sequence consisting of about 10 to 80 amino acids, the amino acid sequence having a sequence identity at least 90% homologous to a portion of SEQ ID NO:1. The polypeptide inhibits binding of Bcl-2 to IP3 recep... | 10/11/2011 |
| 8030921 | Methods for fat signal suppression in magnetic resonance imaging This application is directed to methods for chemical species signal suppression in magnetic resonance imaging procedures, where Dixon techniques are enhanced by continuously sampling techniques. K-space data is acquired during a period of read gradient associated wi... | 10/04/2011 |
| 8030919 | Dark blood balanced steady state free precession imaging Systems, methods, and other embodiments associated with controlling a magnetic resonance imaging (MRI) apparatus to perform a balanced steady state free precession (bSSFP) technique that includes magnetization preparation with differentiated velocity encoding and sp... | 10/04/2011 |
| 8029942 | Fuel cell system with flow field capable of removing liquid water from the high-pressure channels A fuel cell system having flow fields capable to operate like interdigitated flow fields, but in the same time allowing the removal of liquid water collected in the high-pressure channels, throughout individual exhaust passages. In a preferred embodiment, the channe... | 10/04/2011 |
| 8026488 | Methods for positive emission tomography (PET) target image segmentation A method for positive emission tomography (PET) target image segmentation is provided. The method comprises capturing and digitizing image data of a selected target, determining an initial concentration ratio based on an initial source background ratio and an initia... | 09/27/2011 |
| RE42641 | Depth-resolved spectroscopic optical coherence tomography A method is described for determining depth-resolved backscatter characteristics of scatterers within a sample, comprising the steps of: acquiring a plurality of sets of cross-correlation interferogram data using an interferometer having a sample arm with the sample... | 08/23/2011 |
| 7983743 | System and method for noninvasive electrocardiographic imaging (ECGI) Noninvasive systems and methods are provided for determining electrical activity for a heart of a living being. A processor is configured to meshlessly compute data that represents heart electrical activity from a set of noninvasively measured body surface electrica... | 07/19/2011 |
| 7972845 | Human antibodies against LPS derived from transgenic xenomouse The invention described herein provides for human antibodies produced in non-human animals that specifically bind to Pseudomonas aeruginosa Lipopolysaccharide (LPS). The invention further provides methods for making the antibodies in a non-human animal, expre... | 07/05/2011 |
| 7964585 | Composition and method of treating peripheral neuropathy A method of treating diabetic neuropathy in a subject includes administering to a subject having diabetes or at risk of diabetes a therapeutically effective amount of a pharmaceutical composition comprising at least one of sulfasalazine or a composition including 5-... | 06/21/2011 |
| 7964390 | Sensor system A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is supported by the body. The sensing system exhibits a detectable change whe... | 06/21/2011 |
| 7964353 | Methods and compositions for detecting colon cancers This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as colon neoplasia. ... | 06/21/2011 |
| 7949384 | Method to correct magnetic field/phase variations in proton resonance frequency shift thermometry in magnetic resonance imaging PRF shift MRI data is acquired. The PRF shift MRI data may include signals affected by both a desired PRF shift and an undesired PRF shift. Thus, example systems and methods describe manipulating the PRF shift MRI data to make it substantially free of the effects of... | 05/24/2011 |
| 7947802 | Benzoxazine monomers, polymers and compositions Benzoxazine monomers comprising at least one pendant group are described. (Co)Polymers comprising at least one benzoxazine monomer having at least one pendant group are also described. In a preferred embodiment, the pendant group is located in a side chain of the be... | 05/24/2011 |
| 7943675 | Electrolytes for fuel cell electrodes Improved polymer-based materials are described, for example for use as an electrode binder in a fuel cell. A fuel cell according to an example of the present invention comprises a first electrode including a catalyst and an electrode binder, a second electrode, and ... | 05/17/2011 |
| 7940044 | Determining phase-encoding direction for parallel MRI Example systems, methods, and apparatus associated with determining a phase-encoding direction for parallel MRI are described. One example, method includes selecting a set of projection directions along which an MRI apparatus is to apply RF energy to an object to be... | 05/10/2011 |
| 7936802 | Co-extruded multilayer polymers films for all-polymer lasers A polymer film laser is provided that comprises a plurality of extruded polymer layers. The plurality of extruded polymer layers comprises a plurality of alternating dielectric layers of a first polymer material having a first refractive index and a second polymer m... | 05/03/2011 |
| 7935745 | Self-assembled nanofiber templates; versatile approaches for polymer nanocomposites Polymer nanocomposites, nanoparticle-containing organogels utilized in forming the polymer nanocomposites, and methods for forming the polymer nanocomposites and nanoparticle-containing organogels are disclosed. Relatively simple and versatile methods are utilized t... | 05/03/2011 |
| 7929134 | Even frequency spacing spectrometer and optical coherence tomography device This application describes a spectrometer that includes a set of collimating optics to collimate received EMR to produce a collimated EMR. The spectrometer also includes a first dispersive optical element for dispersing the collimated EMR and a second dispersive opt... | 04/19/2011 |
| 7894877 | System and method for adjusting image parameters based on device tracking A system for automatically adapting image acquisition parameters based on imaging and/or device tracking feedback is provided. An example system includes a subsystem for acquiring images (e.g., MR) of an object and tracking data for a device (e.g. catheter) inserted... | 02/22/2011 |
| 7888463 | Modulators of antiestrogen pharmacology A protein, designated ERCoA3 is provided. The ERCoA3 protein interacts with the estrogen receptor and the progesterone receptor and causes activation of these receptors is provided. Also provided are polynucleotides which encode ERCoA3 or block translation of the mR... | 02/15/2011 |
| 7872079 | Naphthoxazine composition The present invention is intended to provide a novel naphthoxazine composition having a smaller amount of volatile components (weight reduction) upon curing, and is to provide a naphthoxazine composition characterized in that a naphthoxazine compound having a phenol... | 01/18/2011 |
