U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

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...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!

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Assignee: Carl Zeiss Meditec, Inc.


Location: Dublin, CA
No. of patents: 39

NumberTitleIssue Date
8132916High precision contrast ratio display for visual stimulus
Embodiments of the present invention include approaches for controlling light valve devices to improve the range and precision of the contrast ratio and the grayscale levels of a display used for visual field tests. In one embodiment, two or more illumination device...
03/13/2012
8115935Method of motion correction in optical coherence tomography imaging
An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set ...
02/14/2012
8085408Spectral domain optical coherence tomography system
An optical coherence tomography device is disclosed for improved imaging. Reduced levels of speckle in the images generated by the device are obtained by forming a B-scan from a plurality of A-scans, wherein each resolution cell of the B-scan is generated through co...
12/27/2011
8079711Method for finding the lateral position of the fovea in an SDOCT image volume
Embodiments of the present invention provide methods for finding the lateral position of the fovea in an OCT image volume. In one instance, a cost function is developed whose minimum is located at or near the foveal center. This cost function includes one or more me...
12/20/2011
8073202Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues
The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface...
12/06/2011
8045176Methods for mapping tissue with optical coherence tomography data
Various methods are disclosed for mapping optical coherence tomography (OCT) data to facilitate review and diagnosis. In one aspect, high resolution 2D line scans are obtained along with lower density 3D cube scans and displayed in a manner to provide context to the...
10/25/2011
7878651Refractive prescription using optical coherence tomography
An optical coherence tomography apparatus and method for measuring refractive power of the human cornea is disclosed. The apparatus collects both the specularly reflected light from the anterior surface of the cornea and diffusely reflected light from the interior o...
02/01/2011
7805009Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system
A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject...
09/28/2010
7798647RNFL measurement analysis
One embodiment of the present invention accounts for individual anatomical variation when evaluating optical nerve fiber measurements. In one aspect, contextual information is used to compensate or correct measurement data. In another aspect, reference coordinates a...
09/21/2010
RE41633Light source for swept source optical coherence tomography based on cascaded distributed feedback lasers with engineered band gaps
The present invention is a tunable semiconductor laser for swept source optical coherence tomography, comprising a semiconductor substrate; a waveguide on top of said substrate with multiple sections of different band gap engineered multiple quantum wells (MQWs); a ...
09/07/2010
7768652Methods for mapping tissue with optical coherence tomography data
Various methods are disclosed for mapping optical coherence tomography (OCT) data to facilitate review and diagnosis. In one aspect, high resolution 2D line scans are obtained along with lower density 3D cube scans and displayed in a manner to provide context to the...
08/03/2010
7755769Method of motion correction in optical coherence tomography imaging
An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set ...
07/13/2010
7668342Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues
The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface...
02/23/2010
7631970Optical apparatus and methods for performing eye examinations
An eye examination system is presented that obtains several parameters of the eye. A system according to some embodiments of the present invention include a keratometry system, a low coherence reflectometry system, and a low coherence interferometry system co-couple...
12/15/2009
7554668Light source for swept source optical coherence tomography based on cascaded distributed feedback lasers with engineered band gaps
The present invention is a tunable semiconductor laser for swept source optical coherence tomography, comprising a semiconductor substrate; a waveguide on top of said substrate with multiple sections of different band gap engineered multiple quantum wells (MQWs); a ...
06/30/2009
7508525High efficiency balanced detection interferometer
An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In one set of embodiments, ...
03/24/2009
7480059Optical coherence tomography for eye-length measurement
An accurate measure of eye length can be obtained using concurrent OCT measurements. A position OCT device can be used to continually monitor the position of the front surface of the cornea, while a distance OCT device can determine the apparent distance between the...
01/20/2009
7456957Littrow spectrometer and a spectral domain optical coherence tomography system with a Littrow spectrometer
A compact conical diffraction Littrow spectrometer is disclosed. The distortion of the conically diffracted spectral component beams is compensated and as a result, the diffracted spectral beams can still be focused into a substantially straight line to shine onto a...
11/25/2008
7452077Image adjustment derived from optical imaging measurement data
A method and apparatus for imaging within the eye is provided whereby a component of eye position is detected using optical imaging data. Tracking eye position over time and correctly registering imaging data for scan locations or using eye position to detect decent...
11/18/2008
7433046Patterned spinning disk based optical phase shifter for spectral domain optical coherence tomography
A low cost patterned spinning disk is disclosed for achieving relatively rapid discrete optical phase shifts for an optical beam. The invention is particularly useful in a spectral domain optical coherence tomography system. The disk contains stepped patterns of dif...
10/07/2008
7401921Motorized patient support for eye examination or treatment
A motorized head supporting and positioning apparatus is disclosed, such as is useful for eye examination or treatment. The apparatus includes head-receiving supports, which can include a forehead rest and a chinrest, which can be linked by a single arm assembly. A ...
07/22/2008
7400410Optical coherence tomography for eye-length measurement
An accurate measure of eye length can be obtained using concurrent OCT measurements. A position OCT device can be used to continually monitor the position of the front surface of the cornea, while a distance OCT device can determine the apparent distance between the...
07/15/2008
7391520Fourier domain optical coherence tomography employing a swept multi-wavelength laser and a multi-channel receiver
The present invention is an alternative Fourier domain optical coherence system (FD-OCT) and its associated method. The system comprises a swept multi-wavelength laser, an optical interferometer and a multi-channel receiver. By employing a multi-wavelength laser, th...
06/24/2008
7388672High efficiency balanced detection interferometer
An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In a first set of embodimen...
06/17/2008
7382464Apparatus and method for combined optical-coherence-tomographic and confocal detection
This invention provides a better apparatus and method for the generation of Optical Coherence Tomography (OCT) and Confocal Scanning Laser Ophthalmoscope (CSLO) images, using a dual-waveguiding module. A dual-waveguiding structure consists of a single-mode and a mul...
06/03/2008
7365856Method of motion correction in optical coherence tomography imaging
An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set ...
04/29/2008
7347554Determining criteria for phakic intraocular lens implant procedures
One embodiment of the present invention is a method for determining whether to perform a phakic intraocular lens implant procedure, which method includes: (a) obtaining an image of an anterior segment of an eye; (b) determining a distance from a crystalline lens to ...
03/25/2008
7342659Cross-dispersed spectrometer in a spectral domain optical coherence tomography system
A spectral-domain optical coherence tomography system using a cross-dispersed spectrometer is disclosed. The interfered optical signal is dispersed by a grating into several orders of diffraction, and these orders of diffraction are separated by an additional disper...
03/11/2008
7330270Method to suppress artifacts in frequency-domain optical coherence tomography
One embodiment of the present invention is a method for suppressing artifacts in frequency-domain OCT images, which method includes (a) providing sample and reference paths with a significant difference in their chromatic dispersion (b) correcting for the effects of...
02/12/2008
7287855Method and system for removing the effects of corneal birefringence from a polarimetric image of the retina
A scanning laser polarimetry (SLP) system that measures retinal nerve fiber layer (RNFL) retardance in a single scan image with improved sensitivity. An external bias retarder in combination with the anterior segment retardance forms a nonzero joint retardance adapt...
10/30/2007
7286227Method and system for removing the effects of corneal birefringence from a polarimetric image of the retina
A scanning laser polarimetry (SLP) system that measures in vivo retinal nerve fiber layer (RNFL) retardance (δN, θN) in a single measurement without a variable corneal compensator (VCC). The diagnostic signal is biased so that the detected RN...
10/23/2007
7145661Efficient optical coherence tomography (OCT) system and method for rapid imaging in three dimensions
An optical coherence tomography (OCT) system including a polarizing splitter disposed to direct light in an interferometer such that the OCT detector operates in a noise-optimized regime. When scanning an eye, the system detector simultaneously produces a low-freque...
12/05/2006
7126693Simple high efficiency optical coherence domain reflectometer design
The present invention discloses simple and yet highly efficient configurations of optical coherence domain reflectometry systems. The combined use of a polarizing beam splitter with one or two polarization manipulator(s) that rotate the returned light wave polarizat...
10/24/2006
6988995Method and system for detecting the effects of Alzheimer's disease in the human retina
A system for the in vivo detection of the effects of AD in the interior of an eye. A scanning polarimeter, including a residual retardance canceling system and an improved anterior segment retardance compensator, produces an optical analysis signal representing the ...
01/24/2006
6741359Optical coherence tomography optical scanner
One embodiment of the present invention is a scanner for a beam of scanning optical coherence tomography (“OCT”) radiation that includes: (a) a source of OCT radiation; (b) a scanner; and (c) scanning optics whose image surface has a negative field curvature.
05/25/2004
6729728Back projection visual field tester
One embodiment of the present invention is a visual field tester that includes: (a) a projection screen; (b) a stimulus projection system that projects a light stimulus onto a first side of the projection screen; and (c) a background projection system that projects ...
05/04/2004
6726325Tracking assisted optical coherence tomography
One embodiment of the present invention is an optical coherence tomography (“OCT”) application apparatus that performs an OCT application on an object. The OCT application apparatus includes: (a) an OCT scanning apparatus which outputs a scanning beam of OCT sca...
04/27/2004
6692126Method and apparatus for measuring a corneal profile of an eye
One or more embodiments of the present invention provide a method and apparatus to determine a corneal thickness profile of an eye. In particular, one embodiment of the present invention is a corneal diagnostic instrument including: (a) a Placido ring ill...
02/17/2004
6688744Back projection visual field tester
One embodiment of the present invention is a visual field tester that includes: (a) a projection screen; (b) a stimulus projection system that projects a light stimulus onto a first side of the projection screen; (c) a background projection system that pr...
02/10/2004
 
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