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Assignee: Cancer Institute


Location: Tokyo, JP
No. of patents: 15

NumberTitleIssue Date
5935786Methods for analyzing PRLTS DNA
A gene is provided which is present in the deletion region of a chromosome common in lung cancer, hepatocellular carcinoma and colorectal cancer and encodes a novel protein, a protein encoded by the gene (PRLTS protein), and a method of discriminating tum...
08/10/1999
5871916ECDN protein and DNA encoding the same
A DNA encoding a novel steroid hormone receptor-like protein was obtained from a human fetal lung cDNA library, and its structure was determined. Further, the protein encoded by the gene was isolated, identified, and designated as an ECDN protein. Further...
02/16/1999
5834245PRLTS proteins and DNA's encoding the same
A gene is provided which is present in the deletion region of a chromosome common in lung cancer, hepatocellular carcinoma and colorectal cancer and encodes a novel protein, a protein encoded by the gene (PRLTS protein), and a method of discriminating tum...
11/10/1998
5763182RPDL protein and DNA encoding the same
The 5'-terminal partial nucleotide sequence of each clone of a human fetal lung tissue CDNA library was determined. A clone having a novel sequence including a sequence homologous to that of the transcriptional control protein of a yeast was selected from...
06/09/1998
5709999Linked breast and ovarian cancer susceptibility gene
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of whi...
01/20/1998
5705341MDC proteins and DNAs encoding the same
The present invention provide a gene present in a commonly deleted region of a chromosome in breast and ovarian cancers and encoding a novel protein, the protein ("MDC protein") encoded by the gene and a method for the diagnosis of cancer by using an anti...
01/06/1998
5693473Linked breast and ovarian cancer susceptibility gene
The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of whi...
12/02/1997
5659016RPDL protein and DNA encoding the same
The 5-terminal partially nucleotide sequence of each clone of a human fetal lung tissue cDNA library was determined. A clone having a novel sequence including a sequence homologous to that of the transcriptional control protein of a yeast was selected fro...
08/19/1997
5631351Antibodies to MDC proteins
The present invention provides an antibody encoded by a gene which is present in a commonly deleted region of a chromosome in breast and ovarian cancers. A monoclonal antibody was prepared by using the protein as antigen and can be utilized in clinical fi...
05/20/1997
5599707Human prohibitin DNA
A human prohibitin gene, a protein coded for by said gene, a gene analysis reagent to be used with them, and a quantitative determination of prohibitin in a biological sample by an immunological technique with the use of an antihuman prohibitin antibody a...
02/04/1997
5559023Tumor suppressor gene
A detailed genetic map on human chromosome 11 was prepared. Then, a commonly deleted region on the chromosome in the tumor tissues of patients with multiple endocrine neoplasia type 1 was identified. Further, by linkage analysis of a family line with this...
09/24/1996
5552526MDC proteins and DNAS encoding the same
The present invention provide a gene present in a commonly deleted region of a chromosome in breast and ovarian cancers and encoding a novel protein, the protein ("MDC protein") encoded by the gene, a method for the diagnosis of cancer by using an antibod...
09/03/1996
5463026Anti-human prohibitin antibodies
An antibody which specifically binds with a human prohibitin or a partial structural fragment thereof can be used as a diagnostic agent in the detection of cancer. The human prohibitin has the structure illustrated in SEQ ID NO:1....
10/31/1995
5401635Nucleic acids encoding human prohibitin mutants and detection thereof
A human prohibitin gene, a protein coded for by said gene, a gene analysis reagent to be used with them, and a quantitative determination of prohibitin in a biological sample by an immunological technique with the use of an antihuman prohibitin antibody a...
03/28/1995
5352775APC gene and nucleic acid probes derived therefrom
A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer pati...
10/04/1994
 
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