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Assignee: Cambridge Scientific, Inc.


Location: Belmont, MA
No. of patents: 11

NumberTitleIssue Date
6899107Osteoinduction of cortical bone allografts by coating with biopolymers seeded with recipient periosteal bone cells
A method by which immune responses to cortical bone grafts and other substrates (e.g., cement, IPN, etc.) can be minimized and at the same time graft osteoinductive potential can be improved, and improved graft substrate materials are disclosed. The method of the in...
05/31/2005
6548002Method of making a biodegradable interbody spinal fusion devices
A resorbable interbody fusion device for use in spinal fixation is disclosed. The device is composed of 25-100% bioresorbable or resorbable material. The interbody fusion device of the invention can be in any convenient form, such as a wedge, screw or cag...
04/15/2003
6486232Bioerodible polymeric semi-interpenetrating network alloys for internal fixation devices and bone cements
A bioerodible polymeric material, and in particular a semi-interpenetrating network ("semi-IPN") alloy, is disclosed. A beneficial end use of this material is in the form of internal fixation devices (IFDs) (such as bone supports, plates, and pins) and as...
11/26/2002
6419945Buffered resorbable internal fixation devices and methods for making material therefore
An internal fixation device and a bioerodible implantable material useful therefor comprise a bioerodible polymer that produces acidic products or low molecular weight resorbable fragments upon hydrolytic degradation, and a buffering or neutralizing agent...
07/16/2002
6241771Resorbable interbody spinal fusion devices
A resorbable interbody fusion device for use in spinal fixation is disclosed. The device is composed of 25-100% bioresorbable or resorbable material. The interbody fusion device of the invention can be in any convenient form, such as a wedge, screw or cag...
06/05/2001
6153664Bioerodible polymeric semi-interpenetrating network alloys and internal fixation devices made therefrom
A bioerodible cement system, which, upon mixing of the system parts, forms a cured bioerodible cement, said system comprising a first part comprising a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation; and a secon...
11/28/2000
6071982Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same
A bioerodible polymeric semi-IPN alloy which comprises a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation; a second bioerodible polymer, which provides a biopolymeric scaffolding or internal reinforcement; and opt...
06/06/2000
5817328Material for buffered resorbable internal fixation devices and method for making same
A bioerodible implantable material, comprising a bioerodible polymer that produces acidic products upon hydrolytic degradation, and a buffering compound that buffers the acidic products and maintains the local pH within a desired range. The buffer compoun...
10/06/1998
5512218Method of making biopolymer-based nonlinear optical materials
A biopolymer film and other materials that exhibit nonlinear optical (NLO) properties and a method for making this film. Alignment of biopolymer molecules, which is required for NLO phenomena, is achieved by application of an electric field parallel to th...
04/30/1996
5456917Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
A method for making an implantable bioerodible material for the sustained release of a medicament and the material made from the method. The method comprises the formulation of a biomaterial polymeric carrier into particles of predetermined density and si...
10/10/1995
5429822Biodegradable bursting release system
A biodegradable polymeric multiphasic release system of one or more biodegradable bursting units capable of delivering biologically active substances in a burst or pulse at predetermined times and a method for constructing those units is disclosed. The in...
07/04/1995
 
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