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| Number | Title | Issue Date |
| 7426442 | Software for the display of chromatographic separation data Techniques for displaying chromatographic data using a graphical user interface are provided. Chromatographic separation data that is a series of measurements for a sample at a scanning location over time can be displayed on a display device in a series of bands. Ad... | 09/16/2008 |
| 7276330 | Devices, systems and methods for time domain multiplexing of reagents Time dependent iterative reactions are carried out in microscale fluidic channels by configuring the channels such that reagents from different sources are delivered to a central reaction zone at different times during the analysis, allowing for the performance of a... | 10/02/2007 |
| 7247274 | Prevention of precipitate blockage in microfluidic channels The present invention provides novel microfluidic devices and methods for preventing/ameliorating formation of precipitate blockages in microfluidic devices. In particular the devices and methods of the invention utilize microchannels of specific cross-sectional con... | 07/24/2007 |
| 6834240 | Software for the display of chromatographic separation data Techniques for displaying chromatographic data using a graphical user interface are provided. Chromatographic separation data that is a series of measurements for a sample at a scanning location over time can be displayed on a display device in a series of bands. Ad... | 12/21/2004 |
| 6756019 | Microfluidic devices and systems incorporating cover layers The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid commun... | 06/29/2004 |
| 6733645 | Total analyte quantitation Methods for determining total analyte concentrations and amounts, especially in combination with analyte separations are provided. Microfluidic devices are used to separate analyte mixtures and detect the individual analytes. Signal areas are summed for each individ... | 05/11/2004 |
| 6716394 | DNA sequencing using multiple fluorescent labels being distinguishable by their decay times A method is provided for identifying components of a mixture by labeling the individual components with fluorescent agents having different fluorescence lifetimes. The components are subsequently separated, fluorescent labels detected and their lifetimes measured. B... | 04/06/2004 |
| 6709559 | Microfabricated structures for facilitating fluid introduction into microfluidic devices Fluid introduction is facilitated through the use of a port which extends entirely through a microfluidic substrate. Capillary forces can be used to retain the fluid within the port, and a series of samples or other fluids may be introduced through a single port by ... | 03/23/2004 |
| 6504607 | Light source power modulation for use with chemical and biochemical analysis Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modu... | 01/07/2003 |
| 6468761 | Microfluidic in-line labeling method for continuous-flow protease inhibition analysis Enzyme assays are performed in microfluidic devices including, e.g., in-line labeling, separation, and detection of assay products. In-line labeling allows assays, e.g., protease assays, to be performed in a continuous flow microfluidic format. Also inclu... | 10/22/2002 |
| 6425972 | Methods of manufacturing microfabricated substrates The present invention is directed to improved methods and apparatuses for manufacturing microfabricated devices, and particularly, microfluidic devices. In general the methods and apparatuses of the invention provide improved methods of bonding substrates... | 07/30/2002 |
| 6326083 | Surface coating for microfluidic devices that incorporate a biopolymer resistant moiety Hydrophilic protein adsorption resistant coatings for microfluidic devices are provided. Additionally, microfluidic devices and methods of manufacturing microfluidic devices that include the coatings are provided.... | 12/04/2001 |
| 6238538 | Controlled fluid transport in microfabricated polymeric substrates Microfluidic devices are provided for the performance of chemical and biochemical analyses, syntheses and detection. The devices of the invention combine precise fluidic control systems with microfabricated polymeric substrates to provide accurate, low co... | 05/29/2001 |
| 6156181 | Controlled fluid transport microfabricated polymeric substrates Microfluidic devices are provided for the performance of chemical and biochemical analyses, syntheses and detection. The devices of the invention combine precise fluidic control systems with microfabricated polymeric substrates to provide accurate, low co... | 12/05/2000 |
| 6004515 | Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems The present invention is generally directed to methods, apparatus and systems for use in performing in situ dilution or concentration of a particular subject material in a microfluidic device or system. These methods and apparatus may generally be integra... | 12/21/1999 |
| 5958203 | Electropipettor and compensation means for electrophoretic bias The present invention provides for techniques for transporting materials using electrokinetic forces through the channels of a microfluidic system. The subject materials are transported in regions of high ionic concentration, next to spacer material regio... | 09/28/1999 |
