Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8367815 | Modular polynucleotides for ligand-controlled regulatory systems The invention provides an improved design for the construction of extensible nucleic acid-based, ligand-controlled regulatory systems, and the nucleic acid regulatory systems resulting therefrom. The invention contemplates improving the design of the switches (ligan... | 02/05/2013 |
| 8367386 | Cytochrome P450 oxygenases Nucleic acids encoding cytochrome P450 variants are provided. The cytochrome P450 variants of have a higher alkane-oxidation capability, alkene-oxidation capability, and/or a higher organic-solvent resistance than the corresponding wild-type or parent cytochrome P45... | 02/05/2013 |
| 8362839 | Cross-differential amplifier A cross-differential amplifier is provided. The cross-differential amplifier includes an inductor connected to a direct current power source at a first terminal. A first and second switch, such as transistors, are connected to the inductor at a second terminal. A fi... | 01/29/2013 |
| 8361982 | Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell. In a f... | 01/29/2013 |
| 8361922 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitr... | 01/29/2013 |
| 8361787 | Method for expression of small RNA molecules within a cell The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to express doubles stranded RNA complexes. Small interfering RNA (siRNA) can be expressed using the methods of ... | 01/29/2013 |
| 8361738 | Methods for quantitative target detection and related devices and systems Described herein is a method for detection of a target in a sample and related devices and systems. ... | 01/29/2013 |
| 8361250 | Amorphous platinum-rich alloys According to embodiments of the present invention, an amorphous alloy includes at least Pt, P, Si and B as alloying elements, and has a Pt weight fraction of about 0.925 or greater. In some embodiments, the Pt weight fraction is about 0.950 or greater. ... | 01/29/2013 |
| 8356763 | Mechanical lysis arrangements and methods Methods and arrangements to lyse a biological sample are described. The arrangements comprise a lysis tube containing the sample, one or more electromagnets generating a magnetic field, and one or more permanent magnets inside the lysis tube. The permanent magnets m... | 01/22/2013 |
| 8355768 | Micromachined neural probes A neural probe includes at least one shaft, at least one first electrode disposed on a first side of the at least one shaft, and at least one second electrode disposed on a second side of the at least one shaft. The at least one second electrode is separately addres... | 01/15/2013 |
| 8354075 | Streamline-based microfluidic device The present invention provides a streamline-based device and a method for using the device for continuous separation of particles including cells in biological fluids. The device includes a main microchannel and an array of side microchannels disposed on a substrate... | 01/15/2013 |
| 8350625 | Adaptive power amplifier A power amplifier circuit comprising a scalable power amplifier including an input and an output, and a plurality of activated amplifier elements operative to produce an output signal at the output, and operative to dynamically vary a power output level of the outpu... | 01/08/2013 |
| 8350578 | Wiring nanoscale sensors with nanomechanical resonators A system, device, method, and apparatus provide the ability to wire a voltage sensitive device to a nanoelectromechanical system (NEMS) resonator. A voltage sensitive device is configured to detect one or more voltage signals and output one or more electrical potent... | 01/08/2013 |
| 8348999 | In-situ formation of a valve The present invention satisfies the long felt need for a more compact and durable valve which may be formed in situ. The present invention provides a self-deployable valve system, a method of delivery, and a method of manufacturing for the self-deployable valve syst... | 01/08/2013 |
| RE43896 | Image and video indexing scheme for content analysis The present invention provides an image and video indexing scheme for content analysis. According to the invention, a database of images or videos is compressed. By examining patterns in the compression scheme of each image or video, the present invention identifies... | 01/01/2013 |
| D673482 | Mars rover | 01/01/2013 |
| 8340435 | Method and system for object recognition search A method for object recognition using shape and color features of the object to be recognized. An adaptive architecture is used to recognize and adapt the shape and color features for moving objects to enable object recognition. ... | 12/25/2012 |
| 8338552 | Co-polymer films for sensors Embodiments include a sensor comprising a co-polymer, the co-polymer comprising a first monomer and a second monomer. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the second monomer is poly-4-vinyl pyridinium propylamine chloride. For some e... | 12/25/2012 |
| 8338387 | Small molecule stimulators of neuronal growth Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of treatment, prevention, or amelioration of a variety of medical conditions a... | 12/25/2012 |
| 8336387 | Microfabricated implantable wireless pressure sensor for use in biomedical applications and pressure measurement and sensor implantation methods A variable capacitor, a microfabricated implantable pressure sensor including a variable capacitor and an inductor, and related pressure measurement and implantation methods. The inductor may have a fixed or variable inductance. A variable capacitor and pressure sen... | 12/25/2012 |
| 8331886 | Dynamic scalable concurrent communication and multi-core receiver architecture An integrated multi-core RF device includes a common amplifier which outputs an amplified RF signal. A common transmission line is configured to supply the amplified RF signal to a plurality of common transmission line distribution connections. Each receiver core of... | 12/11/2012 |
| 8329882 | Genetic control of mammalian cells with synthetic RNA regulatory systems The present application relates to nucleic acids that encode a RNA switch responsive to a ligand that can control the expression of a gene product that affects the cell fate determination of a mammalian cell are provided. In some embodiments, the system can be used ... | 12/11/2012 |
| 8329452 | Active NEMS arrays for biochemical analyses A biofunctionalized nanoelectromechanical device (BioNEMS) for sensing single-molecules in solution by measuring the variation in the mechanical displacement of the BioNEMS device during a binding event is provided. The biofunctionalized nanoelectromechanical device... | 12/11/2012 |
| 8329162 | Targeted gene delivery for dendritic cell vaccination Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used t... | 12/11/2012 |
| 8327709 | Method and apparatus for nondestructive evaluation and monitoring of materials and structures A method and apparatus for nondestructive evaluation (NDE) of structures and materials using a highly nonlinear medium for the generation and detection of one or multiple highly nonlinear pulses (or highly nonlinear waves) impinging on a material or structure. The a... | 12/11/2012 |
| 8325988 | Image reconstruction by position and motion tracking A system, method, and apparatus provide the ability to reconstruct an image from an object. A hand-held image acquisition device is configured to acquire local image information from a physical object. A tracking system obtains displacement information for the hand-... | 12/04/2012 |
| 8325349 | Focal plane adjustment by back propagation in optofluidic microscope devices Embodiments of the present invention relate to techniques for improving optofluidic microscope (OFM) devices. One technique that may be used employs surface tension at a hydrophobic surface to passively pump the fluid sample through the fluid channel. Another techni... | 12/04/2012 |
| 8323488 | IC-processed polymer nano-liquid chromatoraphy system on-a-chip and method of making it Embodiments in accordance with the present invention relate to packed-column nano-liquid chromatography (nano-LC) systems integrated on-chip, and methods for producing and using same. The microfabricated chip includes a column, flits/filters, an injector, and a dete... | 12/04/2012 |
| 8319549 | Self-healing power amplifier: methods and apparatus An integrated power amplifier includes a divider and a combiner. The integrated power amplifier also includes two or more amplifiers. Each of the amplifier input terminals is electrically coupled to a divider output terminal and each of the amplifier output terminal... | 11/27/2012 |
| 8318921 | Triggered RNAi The present application relates to methods and compositions for triggering RNAi. Triggered RNAi is highly versatile because the silencing targets are independent of the detection targets. In some embodiments, a method of silencing a target gene is provided. The meth... | 11/27/2012 |
| 8318474 | Engineered yeast cells and uses thereof The present application provides engineered yeast cells and uses thereof. In specific embodiments, the yeast cells have a mutation in the GAL2 gene. In specific embodiments, the yeast cells can be used for producing a protein or compound of interest. ... | 11/27/2012 |
| 8318446 | DNA-damage-induced proteolysis The present application provides methods for identifying compounds for inhibiting DNA damage-induced Htt proteolysis, and methods and compositions for protecting cells from DNA damage-induced cleavage of Htt. ... | 11/27/2012 |
| 8318146 | Ascarosides as nematode sex pheromones A pheromonal compound produced by Caenorhabditis elegans has been identified as 5R-(3′-O-[β-D-glucosyl]-tetrahydro-3′R,5′R-dihydroxy-6′S-methyl-2H-pyran-2′R-yloxy)-2-hexanone. The novel compound, in combination with other ascarosides, elicit a syne... | 11/27/2012 |
| 8316104 | Method and apparatus for collaborative system A collaborative system that includes automatic monitoring and management of reflector/servers and clients. The reflectors are in a logical cluster although their physical locations may be anywhere in the world. Reflector to reflector performance and status is contin... | 11/20/2012 |
| 8314933 | Optofluidic microscope device with photosensor array Embodiments of the present invention relate to techniques for improving optofluidic microscope (OFM) devices. One technique which may be used eliminates the aperture layer covering the light detector layer. Other techniques retain the aperture layer, reversing the r... | 11/20/2012 |
| 8310677 | Micro-cavity gas and vapor sensors and detection methods Micro-cavity gas or vapor sensors and gas or vapor detection methods. Optical energy is introduced into a resonant micro-cavity having a deformable coating such as a polymer. The coating swells or expands when it is exposed to or absorbs a gas or vapor, thereby chan... | 11/13/2012 |
| 8309359 | Isobaric tags for analyte detection and quantification Isobaric reagents for labeling analytes are provided. The isobaric reagents have facile design and synthesis that allows for differential labeling of an unlimited number of analyte samples. ... | 11/13/2012 |
| 8305106 | Electronic self-healing methods for radio-frequency receivers Systems and methods for providing self-healing integrated circuits. The method is characterized in that the behavior of a circuit or a device in response to an input signal is observed. One or more operational parameters or characteristics of the circuit or the devi... | 11/06/2012 |
| 8302904 | Dynamic roughness for aerodynamic applications Systems and methods for providing dynamic control to a surface immersed in a dynamic fluid. The systems and methods of the invention relate to one or more morphable surfaces that can be control in an active manner to provide asperities that interact with a fluid mov... | 11/06/2012 |
