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A forehead support apparatus for resting a standing users forehead against a wall above a bathroom commode or urinal or beneath a showerhead.
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| Number | Title | Issue Date |
| 7824380 | Method for mounting a gasket on a plunger A gasket 7 used for a prefilled syringe 1 in which liquid 3 is filled, having a constriction 8 on its circumferential side face in contact with an inner surface of a syringe barrel 2 and having a bottom face 7c which ... | 11/02/2010 |
| 7820621 | Compounds for targeting endothelial cells, compositions containing the same and methods for their use The present invention provides compounds for targeting endothelial cells, tumor cells or other cells that express the NP-1 receptor, compositions containing the same and methods for their use. Additionally, the present invention includes diagnostic, therapeutic and ... | 10/26/2010 |
| 7794693 | Targeting vector-phospholipid conjugates Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly usefu... | 09/14/2010 |
| 7666979 | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same Methods for the preparation of multivalent constructs for therapeutic and diagnostic applications are provided. More specifically, novel methods for preparing multivalent constructs comprising the formula A-B-C-D-E-B′-F for therapeutic and diagnostic applications ... | 02/23/2010 |
| 7582280 | Conjugates of antioxidants with metal chelating ligands for use in diagnostic and therapeutic applications The invention provides radiopharmaceuticals for diagnostic and therapeutic applications, conjugates of antioxidants with metal chelating ligands, intermediate compounds, methods of making such radiopharmaceuticals, ligands, and intermediate compounds, and kits for p... | 09/01/2009 |
| 7509784 | Method for the preparation of pre-filled plastic syringes A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the... | 03/31/2009 |
| 7422733 | Linkable sialyl Lewis X analogs Disclosed herein is a class of linkable tetrasaccharide compounds that includes the amino phenyl glycoside of sialyl Lewis X (SLeX) and related analogs. These compounds have conjugatable nucleophilic groups, making them useful in preparing multimeric SLe | 09/09/2008 |
| 7407644 | Conjugates of antioxidants with metal chelating ligands for use in diagnostic and therapeutic applications The invention provides radiopharmaceuticals for diagnostic and therapeutic applications, conjugates of antioxidants with metal chelating ligands, intermediate compounds, methods of making such radiopharmaceuticals, ligands, and intermediate compounds, and kits for p... | 08/05/2008 |
| 7399460 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α, γ, or bis isomers of folate receptor-binding analogs of folate, a me... | 07/15/2008 |
| 7385041 | Dual functioning excipient for metal chelate contrast agents A novel dual functioning excipient for metal chelate contrast agents is disclosed. The present excipient, Xm[X′(L′)]n, which is the calcium or zinc salt of the calcium or zinc complex of an organic ligand, enhances safet... | 06/10/2008 |
| 7351389 | Aminocarboxylate ligands having substituted aromatic amide moieties Novel metal-chelate complexes comprising aminocarboxylate ligands including substituted aromatic amide moieties, such as those having the formula wherein R13, A1, R1 and R2 are as... | 04/01/2008 |
| 7261876 | Multivalent constructs for therapeutic and diagnostic applications The invention provides compositions and methods for therapeutic and diagnostic applications. ... | 08/28/2007 |
| 7211240 | Multivalent constructs for therapeutic and diagnostic applications The invention provides compositions and methods for therapeutic and diagnostic applications. ... | 05/01/2007 |
| 7186397 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α, γ, or bis isomers of folate receptor-binding analogs of folate, a me... | 03/06/2007 |
| 7160535 | Conjugates of antioxidants with metal chelating ligands for use in diagnostic and therapeutic applications The invention provides radiopharmaceuticals for diagnostic and therapeutic applications, conjugates of antioxidants with metal chelating ligands, intermediate compounds, methods of making such radiopharmaceuticals, ligands, and intermediate compounds, and kits for p... | 01/09/2007 |
| 7109167 | Compounds for targeting endothelial cells, compositions containing the same and methods for their use The present invention provides compounds for targeting endothelial cells, tumor cells or other cells that express the NP-1 receptor, compositions containing the same and methods for their use. Additionally, the present invention includes diagnostic, therapeutic and ... | 09/19/2006 |
| 7083778 | Ultrasound contrast agents and methods of making and using them Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain surfactants and, optionally, hydrophilic stabilizers. The surfactants can be in the form of liposomes. The suspensions are obtained b... | 08/01/2006 |
| RE39146 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditio... | 06/27/2006 |
| 6989141 | Ultrasound contrast agents and methods of making and using them Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The su... | 01/24/2006 |
| 6958141 | Rhenium and technetium complexes containing a hypoxia-localizing moiety Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radion... | 10/25/2005 |
| 6933391 | Methods of synthesizing heteroatom-bearing ligands and intermediate used therefor The invention provides improved and simplified methods of synthesizing ligands containing a heteroatom-bearing bridge using a novel intermediate compound. The ligands may be used to form metal complexes that are useful in diagnostic and therapeutic applications.... | 08/23/2005 |
| 6897311 | Process for the preparation of decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]acenaphthylene and functionalized derivatives A process for the preparation of compound of formula (I A), decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]accnaphthylene and the corresponding functionalized compounds of general formula (I), intermediates for the preparation of 1,4,7,10-tetraazacyclododecane (II A) an... | 05/24/2005 |
| 6896875 | Mixable combination for generating a suspension of stable microbubbles for ultrasonic imaging Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The su... | 05/24/2005 |
| 6881397 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditio... | 04/19/2005 |
| 6875864 | Aminocarboxylate ligands having substituted aromatic amide moieties Novel metal-chelate complexes comprising aminocarboxylate ligands including substituted aromatic amide moieties, such as those having the formula wherein R13, A1, R1 and R2 a... | 04/05/2005 |
| 6803046 | Sincalide formulations The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention also features kits and methods for preparing improved sincalide formul... | 10/12/2004 |
| 6719733 | Method for the preparation of pre-filled plastic syringes A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the... | 04/13/2004 |
| 6699458 | Rhenium and technetium complexes containing a hypoxia-localizing moiety Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide c... | 03/02/2004 |
| 6693190 | Enhanced relaxivity monomeric and multimeric compounds Metal chelates capable of exhibiting an immobilized relativity between about 60 and 200 mM-1 s-1 /metal atom are useful as magnetic resonance imaging agents. Additionally, a compound which is useful as a metal-chelating ligand has th... | 02/17/2004 |
| 6660246 | Ligands and metal complexes thereof Novel compounds of the formula ##STR1## and novel complexes of these compounds with metals are useful in diagnostic and therapeutic methods.... | 12/09/2003 |
| 6653470 | Process for the preparation of 1,4,7,10-tetraazacyclododecane 1,4,7,10-Tetraazacyclodecane, a precursor for the synthesis of macrocylic chelating agents for metal ions such as gadolinium, is prepared efficiently as a highly pure product on an industrial scale.... | 11/25/2003 |
| 6652834 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents Substituted polycarboxylic ligand molecules and corresponding metal complexes of said ligands, preferably paramagnetic metals complexes for generating responses in the field of magnetic resonance imaging (MRI) The paramagnetic complexes of the polycarboxy... | 11/25/2003 |
| 6613306 | Ultrasound contrast agents and methods of making and using them Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain surfactants and, optionally, hydrophilic stabilizers. The surfactants can be in the form of liposomes. The suspensions are... | 09/02/2003 |
| 6592846 | Long-lasting aqueous dispersions or suspensions of pressure resistant gas-filled microvesicles and methods for thereof preparation thereof One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standa... | 07/15/2003 |
| 6589506 | Method for magnetic resonance imaging of the lung A method for the assessment of pulmonary ventilation and lung perfusion through Magnetic Resonance Imaging (MRI), comprising the steps of: positioning a human subject in an MRI apparatus, delivering a hyperpolarized noble gas to the subject by inhalation, foll... | 07/08/2003 |
| 6585955 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standa... | 07/01/2003 |
| 6506938 | Process for the purifying of iopamidol A process for purifying Iopamidol which uses a butanol as solvent is described. Iopamidol is obtained with high yields, also starting from aqueous solutions of the same and has characteristics in accordance with those required by pharmacopoeia.... | 01/14/2003 |
| 6485705 | Mixable combination for generating a suspension of stable microbubbles for ultrasonic imaging Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposo... | 11/26/2002 |
| 6420603 | Process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide A novel process for the preparation of N,N'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2,4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as lomeprol, a novel non-ionic contrast agent which shows very good safety an... | 07/16/2002 |
| 6359120 | Rhenium and technetium complexes containing a hypoxia-localizing moiety Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined ... | 03/19/2002 |
