Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 7604983 | Apparatus and methods for parallel processing of micro-volume liquid reactions Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array o... | 10/20/2009 |
| 7332271 | Apparatus and methods for parallel processing of micro-volume liquid reactions Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array o... | 02/19/2008 |
| 7319372 | In-plane mechanically coupled microelectromechanical tuning fork resonators There are many inventions described and illustrated herein, as well as many aspects and embodiments of those inventions. In one aspect, the present invention is directed to a resonator architecture including a plurality of in-plane vibration microelectromechanical r... | 01/15/2008 |
| 7288892 | Plasma display panel with improved cell geometry A cell geometry for a coplanar electrode plasma display panel consisting of two transparent plates, one with parallel sustain electrodes, and the other with address electrodes deposited on their surface. The electrodes are covered with a dielectric film. A protectiv... | 10/30/2007 |
| 7274623 | Method and system for operating capacitive membrane ultrasonic transducers A novel operation regime for capacitive micromachined ultrasonic transducers (cMUTs). The collapse-snapback operation in which the center of the membrane makes intermittent contact with the substrate. This combines two distinct states of the membrane (in-collapse an... | 09/25/2007 |
| 7232842 | Kinase inhibitors and associated pharmaceutical compositions and methods of use The invention provides novel compounds useful as kinase inhibitors or as starting materials And/or intermediates in the synthesis of compounds useful as kinase inhibitors. The compounds have The general structure of formula (I) | 06/19/2007 |
| 7130042 | Dual axis fluorescence microscope with modulated input A dual beam confocal microscope is provided. An optical source assembly provides two mutually coherent optical beams differing in frequency by a frequency difference Δf. The two beams are received by focusing assemblies that provide two focused beams to a sample. T... | 10/31/2006 |
| 7089787 | Torsional harmonic cantilevers for detection of high frequency force components in atomic force microscopy A cantilever for the use in atomic force microscopy includes a cantilever arm having a fixed end being attached to a base member and a free end where the cantilever arm has a first shape and an axis of torsion associated with the first shape, and a probe tip project... | 08/15/2006 |
| 6982082 | Gene therapy by cell specific targeting This invention is directed to a modified cyclosporin A and to a modified, genetically engineered version of its receptor, cyclophilin. This invention is further directed to a method for treating host versus graft disease following blood marrow transplantation by tra... | 01/03/2006 |
| 6891021 | Regulated apoptosis We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genet... | 05/10/2005 |
| 6801939 | Method for evaluating quality of service of a digital network connection A technique for measuring, evaluating, and presenting virtual network connection latency and virtual network connection stability information allows users to easily evaluate the quality of internet connections in real time. The technique uses audible sounds to repre... | 10/05/2004 |
| 6789426 | Microfluidic channels with integrated ultrasonic transducers for temperature measurement and method There is described a method and apparatus for measuring temperature of a fluid in a microchannel of the type having spaced walls. An ultrasonic transducer transmits ultrasonic waves transmitted from one wall to the opposite wall. A processor determines the time-of-f... | 09/14/2004 |
| 6750040 | Cell-free synthesis of polyketides Cell-free systems which effect the production of polyketides employing modular polyketide synthases are described. Libraries of new and/or known polyketides may also be produced in cell-free systems employing aromatic PKS, modular PKS or both. ... | 06/15/2004 |
| 6605115 | Method and composition for inhibiting cardiovascular cell proliferation Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, ... | 08/12/2003 |
| 6442566 | Frame-based knowledge representation system and methods A frame-based knowledge representation system is built on a relational database that is completely transparent to the user. A user at a client machine sends standard knowledge base queries across a distributed computer system and the system translates the... | 08/27/2002 |
| 6388052 | NF-AT polypeptides and polynucleotides The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplificatio... | 05/14/2002 |
| 6365891 | Optical sensor array having multiple rungs between distribution and return buses and having amplifiers in the buses to equalize return signals The present invention significantly improves the signal to noise ratio (SNR) in a passive optical array comprising sensors located in rungs between a distribution bus and a return bus. Erbium-doped optical fiber amplifiers are included in the buses proxim... | 04/02/2002 |
| 6356385 | Inhomogeneous broadening to modify the gain of an optical amplifier An optical amplifier has a gain profile which is substantially flat and independent, over a wide range, of the pump power, power of the input signals, and the number of input signals. The amplifier utilizes an optical resonator having a gain medium whose ... | 03/12/2002 |
| 6300626 | Time-of-flight mass spectrometer and ion analysis An ion beam supplied from a source is modulated so that ions at a constant flux is passed during on periods or portions thereof and are deflected or stopped during off periods according to a binary sequence in order to encode the ion beam with phase infor... | 10/09/2001 |
| 6165977 | Isozyme-specific activators of protein kinase C methods and compositions Isozyme-specific agonists or activators of &3xb5;PKC are disclosed. The agonists include peptides corresponding to the region of &3xb5;PKC between about amino acids 85 and 92. Also disclosed are therapeutic methods employing such &3xb5;PKC-specific agonis... | 12/26/2000 |
| 6150099 | NF-AT polypeptides and polynucleotides The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplificatio... | 11/21/2000 |
| 6103473 | Mutagenicity screening method using human DNA polymerase or catalytic polypeptide The human DNA polymerase catalytic polypeptide has been functionally over-expressed by a recombinant baculovirus in insect cells at >1000 fold higher levels than that found in cultured normal human cells.... | 08/15/2000 |
| 6096515 | NF-AT polynucleotides The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplificatio... | 08/01/2000 |
| 6035274 | Strain-sensing goniometers, systems and recognition algorithms Goniometers are provided having internal compensation employing two opposing variable resistance strain sensing elements separated by a flexible film. The goniometers may be used in sets for detecting complex hinge or joint movements, where patterns of hi... | 03/07/2000 |
| 6028305 | Dual cantilever scanning probe microscope This microscope apparatus comprises two probes. The first probe is configured to interact with and measure characteristics of surfaces within an effective measurement distance of the first probe. This probe could be contact type, non-contact type, constan... | 02/22/2000 |
| 6008045 | Nucleic acid encoding human DNA polymerase The human DNA polymerase catalytic polypeptide has been functionally over-expressed by a recombinant baculovirus in insect cells at >1000 fold higher levels than that found in cultured normal human cells.... | 12/28/1999 |
| 5994313 | Regulated apoptosis We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell deat... | 11/30/1999 |
| 5932966 | Electron sources utilizing patterned negative electron affinity photocathodes An electron source includes a negative electron affinity photocathode on a light-transmissive substrate and a light beam generator for directing a light beam through the substrate at the photocathode for exciting electrons into the conduction band. The ph... | 08/03/1999 |
| 5908981 | Interdigital deflection sensor for microcantilevers A deflection sensor for a microcantilever includes two sets of interdigitated fingers, one (reference) set being attached to the substrate from which the microcantilever extends and the other (movable) set being attached to the tip of the microcantilever.... | 06/01/1999 |
| 5888512 | Lymphocyte activity regulation by HLA peptides Fragments from the polymorphic domains of Class I HLA antigen domains are used to modulate T-cell activity. The peptides are from the 댑- or 댒 domains, particularly of the HLA-A, and B antigens. The peptides may be conjugated to other compoun... | 03/30/1999 |
| 5869065 | High molecular weight surface proteins of non-typeable haemophilus High molecular weight surface proteins of non-typeable Haemophilus influenzae which exhibit immunogenic properties and genes encoding the same are described. Specifically, genes coding for two immunodominant high molecular weight proteins, HMW1 and HMW2, ... | 02/09/1999 |
| 5734905 | User interface in object oriented computer system for performing intuitive object transformations A computer system having an object oriented operating system utilizes a user interface that includes a display and user command input apparatus. Objects data structures are stored in the computer system's memory, each object having an associated image tha... | 03/31/1998 |
| 5697370 | Method for increasing temporal resolution of MR fluoroscopy A method is described for increasing the temporal resolution of MR fluoroscopy procedures. A central portion of the image requiring a higher temporal resolution is updated more frequently using less-than-complete newly acquired NMR data. A running average... | 12/16/1997 |
| 5684360 | Electron sources utilizing negative electron affinity photocathodes with ultra-small emission areas An electron source includes a negative electron affinity photocathode on a light-transmissive substrate and a light beam generator for directing a light beam through the substrate at the photocathode for exciting electrons into the conduction band. The ph... | 11/04/1997 |
| 5666514 | Cache memory containing extra status bits to indicate memory regions where logging of data should occur The present invention provides a digital computer memory cache organization for efficient data logging, log-based copy and rollback, high-performance I/O, network switching and multi-cache consistency maintenance. The cache organization implements efficie... | 09/09/1997 |
| 5640256 | Dynamic multiple wavelength filter using a stratified volume holographic optical element A dynamic multiple-wavelength filter which selects at least one wavelength from a beam of radiation incident on a Stratified volume Holographic Optical Element (SVHOE) in accordance with the Bragg condition. The SVHOE has a number n of grating layers i an... | 06/17/1997 |
| 5617028 | Magnetic field inhomogeneity correction in MRI using estimated linear magnetic field map A fast and robust method for correcting magnetic resonance image distortion due to field inhomogeneity is applied to spiral k-space scanning. The method includes acquiring a local field map, finding the best fit to a linear map, and using the linear field... | 04/01/1997 |
| 5614397 | Method and compositions for modulating lifespan of hematolymphoid cells Methods and compositions for modifying the lifespan of progeny cells of mammalian hematopoietic stem cells, particularly myeloid series cells, are provided. Transgenic nonhuman mammals also are provided which produce transgenic myeloid cells having an alt... | 03/25/1997 |
| 5603766 | Method for producing uniaxial tetragonal thin films of ternary intermetallic compounds A method for making oriented thin films of a ternary intermetallic compound and such films having a tetragonal structure and generally uniaxial magnetic, optical, electronic, and mechanical properties, as well as a generally lower Curie temperature than o... | 02/18/1997 |
| 5546209 | One-to-many simultaneous and reconfigurable optical two-dimensional plane interconnections using multiple wavelength, vertical cavity, surface-emitting lasers and wavelength-dependent detector planes Optical communication apparatus for simultaneously and reconfigurably establishing optical communication channels, comprises at least one light source and a plurality of wavelength-selective detectors optically associated with each light source, the detec... | 08/13/1996 |