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| Number | Title | Issue Date |
| 8180997 | Dynamically composing processor cores to form logical processors A method, system and computer program product for dynamically composing processor cores to form logical processors. Processor cores are composable in that the processor cores are dynamically allocated to form a logical processor to handle a change in the operating s... | 05/15/2012 |
| 8055881 | Computing nodes for executing groups of instructions A computation node according to various embodiments of the invention includes at least one input port capable of being coupled to at least one first other 5 computation node, a first store coupled to the input port(s) to store input data, a second store to receive a... | 11/08/2011 |
| 7998417 | Particulate matter sensor with a heater An apparatus to detect particulate matter. The apparatus includes a sensor electrode, a shroud, and a heater. The electrode measures a chemical composition within an exhaust stream. The shroud surrounds at least a portion of the sensor electrode, exclusive of a dist... | 08/16/2011 |
| 7825269 | Ligands for nematode nuclear receptors and uses thereof Anti-nematode compounds, compositions, and methods for identifying such compounds are disclosed, where the compounds have the formula I: where Q, Q′, R1, R2, and n are defined herein. ... | 11/02/2010 |
| 7799518 | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided. ... | 09/21/2010 |
| 7705120 | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided. ... | 04/27/2010 |
| 7589334 | Ion beam delivery equipment and an ion beam delivery method The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for tre... | 09/15/2009 |
| 7576342 | Ion beam delivery equipment and ion beam delivery method The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for tre... | 08/18/2009 |
| 7535549 | System and method for improvement of alignment and overlay for microlithography The present invention provides a method for determining the forces to be applied to a substrate in order to deform the same and correct for overlay misalignment. ... | 05/19/2009 |
| 7531025 | Method of creating a turbulent flow of fluid between a mold and a substrate The present invention is directed toward a method of controlling a turbulent flow of a fluid between a substrate and a template, and more specifically, controlling a turbulent flow of a fluid between droplets disposed on a substrate and a template. To that end, the ... | 05/12/2009 |
| 7432634 | Remote center compliant flexure device An apparatus to control displacement of a body spaced-apart from a surface includes a flexure system having a first flexure member defining a first axis of rotation and a second flexure member defining a second axis of rotation. A body is coupled to the flexure syst... | 10/07/2008 |
| 7429616 | Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds The invention relates to the synthesis and complete stereochemical assignments of cytotoxic compounds such as compound 28-a and its stereoisomers: The invention further provides processes for making the compounds, their syn... | 09/30/2008 |
| 7410788 | Compositions and methods for production of disulfide bond containing proteins in host cells The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide bonds, but whose precursor molecule contained at least one disulfide bo... | 08/12/2008 |
| 7374893 | Peptide mediated synthesis of metallic and magnetic materials The present invention includes methods for producing magnetic nanocrystals by using a biological molecule that has been modified to possess an amino acid oligomer that is capable of specific binding to a magnetic material. ... | 05/20/2008 |
| 7354912 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid. ... | 04/08/2008 |
| 7329642 | β-2-glycoprotein is an inhibitor of angiogenesis The present disclosure provides a method of inhibiting angiogenesis within a tissue of interest by providing either intact or nicked β2-Glycoprotein 1 (β2GP1) to cells associated with the tissue. The presence of β2GP1 inhibits angiogenesis within the tissue, in p... | 02/12/2008 |
| 7304168 | Photo-caged fluorescent molecules A class of photo-caged and cell permeable fluorescent molecules having high uncaging cross sections, robust fluorescence enhancement, and flexible chemistry for bioconjugation. Some of the photo-caged fluorescent molecules are derived from 6-chloro-7-hydroxy-coumari... | 12/04/2007 |
| 7122572 | Calixpyrroles The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be eff... | 10/17/2006 |
| 7067111 | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases... | 06/27/2006 |
| 7033473 | Method and apparatus for combined magnetophoretic and dielectrophoretic manipulation of analyte mixtures Methods and apparatuses for discriminating matter utilizing dielectrophoresis combined with magnetophoresis. A sample having one or more constituents is injected into an inlet port of a chamber. A carrier medium flow is initiated at the inlet port to establish a flo... | 04/25/2006 |
| 6949255 | Inhibitory chemical formulation with preservative system The present invention provides methods for preventing the transmission of HIV, methods for prophylaxis of HIV transmission and methods for reducing the risk of HIV transmission vaginally or rectally using compositions having at least one of polyquaternium, glycerin,... | 09/27/2005 |
| 6872563 | Compositions and methods for production of disulfide bond containing proteins in host cells The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide bonds, but whose precursor molecule contained at least one disulfide bo... | 03/29/2005 |
| 6866762 | Dielectric gate and methods for fluid injection and control A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathw... | 03/15/2005 |
| 6863790 | Sheathless interface for capillary electrophoresis/electrospray ionization-mass spectrometry using an in-capillary electrode A simple and rugged sheathless interface for capillary electrophoresis/electrospray ionization-mass spectrometry (CE/ESI-MS) was designed using common laboratory tools and chemicals. The interface uses a small platinum (Pt) wire which is inserted into the CE capilla... | 03/08/2005 |
| 6862890 | Process for production of nanoparticles and microparticles by spray freezing into liquid The present invention provides a system and a method for the production of microparticles and nanoparticles of materials that can be dissolved. The system and method of the present invention provide quicker freezing times, which in turn produces a more uniform distr... | 03/08/2005 |
| 6825186 | Method and compositions for treating atheroma, tumors and other neoplastic tissue The radiation sensitization potential of a candidate compound can be screened by determine its ability to generate one or more reactive oxygen species under appropriate conditions. Compounds determined to have radiation sensitization potential are employed in method... | 11/30/2004 |
| 6821784 | Method of diagnosing colorectal adenomas and cancer using proton magnetic resonance spectroscopy Two dimensional COSY magnetic resonance spectroscopy of human stool can be used in a non-invasive method of detecting the presence of colorectal cancer. The spectrum of a patient's stool is compared with that of stool from non-cancerous subjects, observed difference... | 11/23/2004 |
| 6806354 | Methods and compositions for inducing autoimmunity in the treatment of cancers Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate comp... | 10/19/2004 |
| 6756062 | Preparation of drug particles using evaporation precipitation into aqueous solutions A method for preparing poorly water soluble drug particles is disclosed. The method comprises dissolving a drug in at least one organic solvent to form a drug/organic mixture, spraying the drug/organic mixture into an aqueous solution, and concurrently evaporating t... | 06/29/2004 |
| 6737052 | Induction of programmed cell death by N5 gene The present invention concerns methods and compositions for treating cancer in a subject. These methods and compositions utilize the activities associated with the N5 gene product, p84N5. p84N5 contains a functional death domain, can interact with the retinoblastoma... | 05/18/2004 |
| 6676892 | Direct selective laser sintering of metals A method of fabricating a fully dense, three dimensional object by direct laser sintering is disclosed. In a chamber with a partial pressure atmosphere, a beam of directed energy melts metallic powder in order to form a solid layer cross section. Another ... | 01/13/2004 |
| 6671539 | Method and apparatus for fabricating orthognathic surgical splints A method of forming a surgical splint to receive a patient's dentition and thereby align the upper jaw and the lower jaw during surgery includes generating a CT computer model of bone structure, generating a digital dental computer model of the patient's ... | 12/30/2003 |
| 6623957 | Secretion of T cell receptor fragments from recombinant host cells Variable domain murine T-cell receptor genes have been isolated and used to construct cloning and expression vectors. V, Vଲ, and single chain V -Vଲ fragments have been expressed as secr... | 09/23/2003 |
| 6617441 | Diagnostic test for borrelia infection Bites from Amblyomma americanum, a hard tick, have been associated with a Lyme disease-like illness in the southeastern and south-central United States. Present in 2% of ticks collected in four states were uncultivable spirochetes. Through use of the poly... | 09/09/2003 |
| 6558955 | Methodology for predicting and/or diagnosing disease Disorders are diagnosed by analyzing biological samples of ad libitum-fed and dietary-restricted individuals to generate frequency distribution patterns representative of molecular constituents of the samples, and comparing the patterns.... | 05/06/2003 |
| 6482795 | Tumor suppressor designated TS10q23.3 A specific region of chromosome 10 (10q23.3) has been implicated by series of studies to contain a tumor suppressor gene involved in gliomas, as well as a number of other human cancers. One gene within this region was identified, and the corresponding cod... | 11/19/2002 |
| 6399273 | Water-processable photoresist compositions Water-processable positive-tone photoresists comprising a water-soluble polymer, wherein the polymer contains a heat-labile functional group that renders the polymer insoluble in water or an aqueous base upon heat treatment, and an acid-labile functional ... | 06/04/2002 |
| 6399633 | Use of 4-H-1-benzopryan-4-one derivatives as inhibitors of smooth muscle cell proliferation The use of 4-H-1-benzopyran-4-one derivatives as inhibitors of smooth muscle cell proliferation. Smooth muscle cell (SMC) proliferation is a critical component of neointimal formation in many animal models of vascular injury, and in many human lesions as ... | 06/04/2002 |
| 6312466 | Prosthesis containing a solution of polyethylene glycol There is disclosed medical prostheses filled with an aqueous solution of polyethylene glycol. The aqueous solution can be a saline solution. There is also disclosed a method of making such medical prostheses. The novel prostheses are useful, for example, ... | 11/06/2001 |
| 6287607 | Potassium calcium citrate compositions and methods therefor A composition useful as a dietary supplement for providing potassium, calcium, and citrate is presented, as well as processes for producing the composition, and methods for using the composition as a dietary supplement. Administration of the composition c... | 09/11/2001 |
