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| Number | Title | Issue Date |
| 8114638 | Arabinitol dehydrogenase from Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously ex... | 02/14/2012 |
| 7892804 | Arabinitol dehydrogenases from Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously ex... | 02/22/2011 |
| 7592163 | Highly active xylose reductase from A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficienc... | 09/22/2009 |
| 7402419 | Phosphite dehydrogenase mutants for nicotinamide cofactor regeneration Phosphite dehydrogenase mutant enzymes were generated that provide relaxed cofactor specificity and increased thermostability over the wild type enzyme. The mutant enzymes are useful for nicotinamide cofactor regeneration. ... | 07/22/2008 |
| 7193072 | Compositions to identify swine genetically resistant to F18 associated diseases The present invention provides non-invasive methods and compositions to differentiate, with a high level of sensitivity and specificity, swine that are genetically susceptible to diseases associated with F18 E. coli infection, from resistant swine. DNA polymo... | 03/20/2007 |
| 7037959 | Biodegradable polymer compositions methods for making same and articles therefrom A polymer composition includes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded to form a ... | 05/02/2006 |
| 6936262 | LktA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in ... | 08/30/2005 |
| 6793927 | Construction of Pasteurella haemolytica vaccines Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for u... | 09/21/2004 |
| 6630543 | Method of making biodegradable polymer compositions A method of making a biodegradable polymer composition including the steps of providing a first component being either one of a thermoplastic poly(hydroxy ester ether) or a synthetic, hydroxy-functional polymer and providing a second component being a nat... | 10/07/2003 |
| 6573093 | Temperature sensitive plasmids of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 06/03/2003 |
| 6495145 | LktA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 12/17/2002 |
| 6423310 | Biological coating with a protective and curative effect for the control of postharvest decay Novel methods and compositions are provided for the biocontrol of plant diseases by use of a biological coating that confers both a protective and a curative effect for the control of postharvest decay. The coating includes chitosan salts, an antagonistic... | 07/23/2002 |
| 6419922 | Candida saitoana compositions for biocontrol of plant postharvest decay Novel methods and compositions are provided for the biocontrol of plant diseases, in particular diseases causing plant postharvest decay. The novel compositions are "biocontrol cocktails" that are combinations of antagonistic microorganisms and antifungal... | 07/16/2002 |
| 6362256 | Biodegradable polymer compositions, methods for making same and articles therefrom A polymer composition includes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded... | 03/26/2002 |
| 6355859 | Interactions between genotype and diet in swine that prevent E. coli associated intestinal disease The present invention relates interactions between genotype and diet that are useful in the dietary control of intestinal disease. Compositions are related that are useful to differentiate, with a high level of sensitivity and specificity, swine that are ... | 03/12/2002 |
| 6331303 | LKTA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 12/18/2001 |
| 6221661 | Hairpin ribozymes A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an R... | 04/24/2001 |
| 6191196 | Biodegradable polymer compositions, methods for making same and articles therefrom A polymer composition uncludes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded... | 02/20/2001 |
| 6054510 | Biodegradable formed article Compositions of the invention include a hydroxy-functional polyester and a natural polymer. Articles can be made from such a composition so as to have sufficiently strong tensile strengths as to form disposable utensils or to have sufficient stretchabilit... | 04/25/2000 |
| 5942435 | Transgenic swine compositions and methods Transgenic swine, and compositions and methods for making and using same, are provided. Central to the invention are porcine (Sus scrofa) embryonic stem cell lines and methods for establishing them. Cells of such lines are transformed with exogenous genet... | 08/24/1999 |
| 5869339 | HIV targeted hairpin ribozymes A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an R... | 02/09/1999 |
| 5866701 | HIV targeted hairpin ribozymes A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an R... | 02/02/1999 |
| 5858785 | HIV targeted ribozymes A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an R... | 01/12/1999 |
| 5858666 | Apparatus and method of detection employing an AC frequency sensor array A transducer for detecting biomolecules comprises a bottom and a top unit. The bottom unit has a set of parallel electrically conductive transmission lines thereon and probes attached to selected locations along each transmission line for binding with the... | 01/12/1999 |
| 5856188 | Hairpin ribozymes A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an R... | 01/05/1999 |
| 5852078 | Biodegradable polyester compositions with natural polymers and articles thereof Compositions of the invention include a hydroxy-functional polyester and a natural polymer. Articles can be made from such a composition so as to have sufficiently strong tensile strengths as to form disposable utensils or to have sufficient stretchabilit... | 12/22/1998 |
| 5849305 | Construction of Pasteurella haemolytica vaccines Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants f... | 12/15/1998 |
| 5840556 | Molecular genetic construction of vaccine strains of pasteurellaceae Tools for genetically engineering Pasteurellaceae are provided. Replication-conditional plasmids which are useful for the Pasteurellaceae have been isolated and characterized. The plasmids can be utilized for delivery of DNA segments into the Pasteurellac... | 11/24/1998 |
| 5824525 | Construction of Pasteurella haemolytica vaccines Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants f... | 10/20/1998 |
| 5693777 | DNA encoding pasteurella haemolytica PhaI restriction endonuclease and methyltransterase Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants f... | 12/02/1997 |
| 5683900 | Pasteurella haemolytica PhaI restriction endonuclcape and methyltranstesase Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants f... | 11/04/1997 |
| 5674733 | Method and materials for introducing DNA into Prevotella ruminicola A method of introducing expressible heterologous DNA into Prevotella ruminicola is provided. The method involves conjugal transfer of a shuttle vector comprising the heterologous DNA operatively linked to a promoter functional in P. ruminicola. The invent... | 10/07/1997 |
| 5587305 | Pasteurella haemolytica transformants Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants f... | 12/24/1996 |
| 5581193 | Multiple source and detection frequencies in detecting threshold phenomena associated with and/or atomic or molecular spectra Multiple frequency sources are used to apply a time varying signal to a scanning tunneling microscope and a current or voltage passing between the electrodes of the microscope is measured by a microwave spectrum/network analyzer which detects simultaneous... | 12/03/1996 |
| 5559328 | Small cavity analytical instruments A sample and the tip portion of an alternating current scanning tunneling microscope are electrically enclosed within a cavity with electrically conductive walls. The dimensions of the cavity are smaller than the wavelength of a component of the AC signal... | 09/24/1996 |
| 5523226 | Transgenic swine compositions and methods Transgenic swine, and compositions and methods for making and using same, are provided. Central to the invention are porcine (Sus scrofa) embryonic stem cell lines and methods for establishing them. Cells of such lines are transformed with exogenous genet... | 06/04/1996 |
| 5504366 | System for analyzing surfaces of samples A system for transporting in a vacuum chamber sample holders and samples between a holder tray and a location for use with a surface analytical instrument is disclosed. Also provided is a system including a microwave coaxial cable connecting the tip termi... | 04/02/1996 |
| 5434842 | Reading and writing stored information by means of electrochemistry By applying a voltage or signal and withdrawing or injecting an electron or electrons to a layer of material, it is possible to write, erase or read data electrochemically. The layer of material has at least one portion that will reversibly change between... | 07/18/1995 |
| 5322784 | Method and materials for introducing DNA into Prevotella ruminicola A method of introducing expressible heterologous DNA into Prevotella ruminicola is provided. The method involves conjugal transfer of a shuttle vector comprising the heterologous DNA operatively linked to a promoter functional in P. ruminicola. The invent... | 06/21/1994 |
| 5252466 | Fusion proteins having a site for in vivo post-translation modification and methods of making and purifying them A hybrid DNA sequence encoding a fusion protein comprising: a first DNA sequence which encodes an amino acid sequence that allows for post-translation modification of the fusion protein; and a second DNA sequence joined end to end with the first DNA seque... | 10/12/1993 |
