Did You Know...
...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5877277 | Octapeptide bombesin analogs A linear (i.e., non-cyclic) analog of biologically active amphibian bombesin, mammalian gastrin-releasing peptide (GRP), or mammalian growth hormone releasing factor (GRF), having an active site and a binding site responsible for the binding of the peptid... | 03/02/1999 |
| 5750646 | Bradykinin analogs with non-peptide bond A linear peptide which is an analog of a naturally occurring, biologically active peptide having an active site and a binding site responsible for the binding of the peptide to a receptor on a target cell, cleavage of a peptide bond in the active site to ... | 05/12/1998 |
| 5091381 | 2H-1,3,4-benzotriazepin-2-ones Peripheral benzodiazepines (BZDs) are useful in treating disorders caused by abnormal level of peripheral benzodiazepene receptor activity and having, in one aspect, the formula: ##STR1## wherein each X, X1, X2, X3, X... | 02/25/1992 |
| 5084443 | Promoting expression of acetylcholine receptors with LHRH antagonist A method for promoting regrowth of damaged nerve tissue in a mammal, the method comprising administering to the mammal a nerve tissue regrowth promoting amount of an LHRH antagonist namely, N-Acetyl -D-Naphthylalanine-D-para-Cl-Phe-D-Phe-Ser-Tyr-D-Arg-Phe... | 01/28/1992 |
| 5084555 | An octapeptide bombesin analog A linear (i.e., non-cyclic) analog of biologically active amphibian bombesin, mammalian gastrin-releasing peptide (GRP), or mammalian growth hormone releasing factor (GRF), having an active site and a binding site responsible for the binding of the peptid... | 01/28/1992 |
| 5073541 | Treatment of small cell lung cancer with somatostatin analogs A method of treating a mammal suffering from cancer by administering to the mammal somatostatin or an analog thereof, the analog being a hexapeptide analog or higher, in a dosage of at least 25 μg/kg/day.... | 12/17/1991 |
| 5010089 | CCK antagonists and their use in treating gastrointestinal disorders In general, the invention features compounds having the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein AR is an indolyl, quinolyl, naphthyl or a mono- or di- R1 substituted naphthyl in which R1 is, inde... | 04/23/1991 |
| 4983567 | Immunomodulators and methods of making same A compound having the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein A is an amino acid identifying group; B is a hydrogen atom, an alkyl group having 1-5, inclusive, carbon atoms, or an aralkyl group having 6-12, inclusive,... | 01/08/1991 |
| 4957915 | Benzodiazepine analogs BZDs of the general formula 1: ##STR1## where: R represents H, alkyl, alkenyl, cycloalkyl or cycloalkenyl each with up to 8 carbon atoms, phenylalkyl with an alkylene chain of 1 to 3 carbon atoms and optionally substituted on the phenyl radical with ... | 09/18/1990 |
| 4902708 | CCK antagonists In general, the invention features compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein each R1 is, independently, an alkyl group having 1-5, inclusive, carbon atoms, an alkoxy group having 1-5, incl... | 02/20/1990 |
| 4894231 | Therapeutic agent delivery system A therapeutic agent delivery system that includes a biodegradable polymer and a therapeutic agent, the delivery system being coated with a barrier substance that decreases the quantity of the agent released from the system, compared to the quantity of the... | 01/16/1990 |
| 4871870 | Immunomodulators and method of making same A compound having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein A is an amino acid identifying group; B is a hydrogen atom, an alkyl group having 1-5, inclusive, carbon atoms, or an aralkyl group having 6-12, inclusive, ... | 10/03/1989 |
| 4814463 | CCK antagonists In general, the invention features CCK antagonist compounds having the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein each R1 is, independently, an alkyl group having 1 to 5, inclusive, carbon atoms, an alkox... | 03/21/1989 |
| 4785003 | N-disubstituted glycine and B-amino-propionic acid derivatives having anti-ulcer activity A compound having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein A is N-AC-Sar, pGlu, or homo-pGlu-; B is an aryl group, a heteroaryl group, a cycloalkyl group, an aralkyl group, a heteroalkyl group, a heteroaralkyl group... | 11/15/1988 |
| 4734414 | Anti-inflammatory and anti-arthritic pyrazolo-[1,5-a]-1,3,5-triazine derivatives, compositions, and method of use therefor The invention features compounds having anti-arthritic activity and having the formula ##STR1## wherein X is an alkyl group having between 1 and 8, inclusive, carbon atoms and Y is a hydroxyalkylamino group having between 2 and 8, inclusive, car... | 03/29/1988 |
| 4652668 | Aromatic amino acid derivatives A compound having the formula: ##STR1## wherein n is 0-5, inclusive; R1 is H or the identifying group of an amino acid; and R2 is H, aralkyl, or alkyl.... | 03/24/1987 |
| 4625026 | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections In one aspect, compounds having antiviral activity and having the general formula: ##STR1## wherein each R2, independently, is H or lower (fewer than 6 carbon atoms) alkyl; each R3, independently, is H or lower alkyl R0 | 11/25/1986 |
| 4598067 | Antiulcer compounds A compound having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein A is N--Ac--Sar, pGlu, or homo-pGlu-; B is an aryl group, a heteroaryl group, a cycloalkyl group, an aralkyl group, a heteroalkyl group, a heteroaralkyl gro... | 07/01/1986 |
| 4565815 | Pyrazolo[1,5-a]-1,3,5-triazines A compound having anti-ulcer activity and having the formula ##STR1## wherein D is H, SH, NH2, OH, R4 S where R4 is a lower alkyl group; E is OH or NH2 ; J is H or aryl; X is CH or N; Y is CH, N, or CT, whe... | 01/21/1986 |
| 4496540 | Therapeutic compounds In one aspect, compounds capable of inhibiting an endopeptidase responsible for a degradation pathway of enkephalin and having the general formula wherein A is one of the aromatic group-containing amino acid residues L-tryptophyl, D-tryptophyl, L-tyrosyl, D-ty... | 01/29/1985 |
| 4495193 | Imidazole compounds which reduce gastric acid secretion A compound having gastric acid secretion reducing activity and having the formula ##STR1## wherein each V and W, independently, is H, --CH2 COOR4 where R4 is H or lower alkyl, --CH2 CN, or ##STR2## ... | 01/22/1985 |
