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Assignee: Biocryst Pharmaceuticals Inc.


Location: Birmingham, AL
No. of patents: 6

NumberTitleIssue Date
7429571Therapeutic furopyrimidines and thienopyrimidines
The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and ...
09/30/2008
7388002Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
Compounds represented by the formula: A is (CH2)nR2, —CH═CH2, CH2—CH═CH2, O(CH2)nR2, CH(OH)CH3, CH(OH)...
06/17/2008
7230119Process for the preparation of substituted pyrrolidine derivatives and intermediates
Two syntheses are provided; one for the preparation of (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol, and other for the preparation of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol is prepared using the achiral ylide prepared from ben...
06/12/2007
6656915Inhibiting T-cell proliferation
Enhancement of T-cell proliferation in a host inhibition is provided by administering 2'-deoxyguanosine and/or prodrug thereof and a PNP inhibitor. The PNP inhibitor has a Ki value of 50 nanomoles or less....
12/02/2003
6576786Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof
The invention relates to a process for preparing substituted cyclopentane derivatives represented by the formula (I) ##STR1## wherein R1, R2, R3, R4, X and Y are as described in the specification, and pharmaceut...
06/10/2003
6387923Imminoribitol PNP inhibitors, preparation thereof and use thereof
Compounds represented by the formula: ##STR1## wherein A is selected from the group consisting of ##STR2## W is NH2 or H; and each X, Y and Z is individually selected from the group consisting of OH, H and halogen provided at least one of X and...
05/14/2002
 
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