...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7635565 | Analyzing blood type with identification of patient by genotyping This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example singl... | 12/22/2009 |
| 7618792 | Multiplexed detection of anti-red cell alloantibodies Disclosed are methods for detecting antibody in a sample, where the antibody targets an antigen expressed by red blood cells or red blood cell ghosts. Rather than detecting the binding events between a particular antigen antibody pair (as in traditional agglutinatio... | 11/17/2009 |
| 7612193 | Primers for exons of variants of RHCE and RHD genes Disclosed are a method and an algorithm for genetic cross-matching based on the comparison of recipient and donor genotypes—and the underlying combinations of alleles and haplotypes. The method of the invention, rather than focusing on phenotype prediction, instea... | 11/03/2009 |
| 7604718 | Dynamically configurable electrode formed of pixels A dynamically configurable electrode includes a first planar electrode and a planar array of pixels in a different plane, wherein a polarizable liquid medium (including electrolyte solutions) is to reside in the gap between electrodes. The pixels are individually ad... | 10/20/2009 |
| 7595279 | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a biomolecule. The biomolecule can be, for example, a nucleic acid, e.g., an ami... | 09/29/2009 |
| 7574305 | Concurrent optimization in selection of primer and capture probe sets for nucleic acid analysis Disclosed is a method of iteratively optimizing two (or more) interrelated sets of probes for the multi-step analysis of sets of designated sequences, each such sequence requiring, for conversion, at least one conversion probe (“primer”), and each converted sequ... | 08/11/2009 |
| 7526114 | Analysis, secure access to, and transmission of array images Systems and methods are provided the autocentering, autofocusing, acquiring, decoding, aligning, analyzing and exchanging among various parties, images, where the images are of arrays of signals associated with ligand-receptor interactions, and more particularly, li... | 04/28/2009 |
| 7427512 | Light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relics on t... | 09/23/2008 |
| 7425416 | Genetic analysis and authentication This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example singl... | 09/16/2008 |
| 7390676 | System and method for programmable illumination pattern generation A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 06/24/2008 |
| 7363170 | Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products Disclosed is a registry system, including member institutions, in which transfusion donors and recipients are registered following genotyping, which would typically take place in a member institution, or a member institution would have access to the genotyping infor... | 04/22/2008 |
| 7358097 | Making a matrix of random encoded arrays Disclosed is an apparatus and method of maintaining chips or arrays of particles, or arrays of particles deposited on chip surfaces, in a designated area on a substrate surface. This is accomplished by having hydrophilic chips or arrays of particles, and a substrate... | 04/15/2008 |
| 7344841 | Real-time monitoring of nucleic acid target-identifying signals This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example singl... | 03/18/2008 |
| 7335153 | Arrays of microparticles and methods of preparation thereof This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of ... | 02/26/2008 |
| 7320864 | Methods of using molecular constructs for detection of biochemical reactions The present invention relates to molecular constructs and methods of their use in detecting biochemical reactions. In particular, the invention relates to a molecular construct having a capture portion and a substrate portion, where the capture portion isolates the ... | 01/22/2008 |
| 7315637 | Image processing and analysis of array data Disclosed are methods of processing images, and in particular aligning and orienting grids from a fluorescent array of signal sources, by linking nearest neighbor sources to form a hexagon, and then using the hexagon lines for alignment and orientation of the grid. ... | 01/01/2008 |
| 7314718 | Method and apparatus for maintaining multiple planar fluid flows The present invention provides a method of performing analyses and assays involving multiple interactions of reagent-containing fluid flows with liquid and solid target substances. The methods of the invention allow the simultaneous manipulation of different fluids ... | 01/01/2008 |
| 7306918 | Determination of the number of tandem repeat nucleotides using encoded probe-displaying beads This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example singl... | 12/11/2007 |
| 7291504 | Assay involving detection and identification with encoded particles A method and apparatus for the manipulation of colloidal particles and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on the ... | 11/06/2007 |
| 7262063 | Directed assembly of functional heterostructures The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self supporting organic (polymeric) film... | 08/28/2007 |
| 7255895 | Method for controlling solute loading of polymer microparticles Solute-loaded polymer microparticles are obtained by immersing microparticles in a bath comprising a selected solute dissolved in a ternary solvent system. A first solvent of the ternary system is a strong solvent for both the solute and the polymer from which the m... | 08/14/2007 |
| 7211183 | Analysis and fractionation of particles near surfaces A method and apparatus for fractionation of a mixture of particles and for particle analysis are provided, in which LEAPS (“Light-controlled Electrokinetic Assembly of Particles near Surfaces”) is used to fractionate and analyze a plurality of particles suspende... | 05/01/2007 |
| 7202038 | Tandem repeat determination by concurrent analysis of multiple tandem duplex configurations Disclosed is a method of analyzing tandem repeats using one or more probes, each such probe may lack an anchoring sequence but contains one or more tandem repeat sequences complementary to the target tandem repeat sequences. In one embodiment, each probe is attached... | 04/10/2007 |
| 7157228 | Genetic analysis and authentication This invention provides compositions and methods for genetic testing of an organism and for correlating the results of the genetic testing with a unique marker that unambiguously identifies the organism. The markers may be internal markers, such as for example singl... | 01/02/2007 |
| 7090759 | Apparatus and method for light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 08/15/2006 |
| 6958245 | Array cytometry A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled elektrokinetic assembly of particles near surfaces relies on t... | 10/25/2005 |
| 6955751 | Light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 10/18/2005 |
| 6797524 | Light-controlled electrokinetic assembly of particles near surfaces A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 09/28/2004 |