Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 7373255 | Method and system for determination of molecular interaction parameters A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises sequentially, without intermediate regeneration or renewal of the imm... | 05/13/2008 |
| 7320879 | Method of determining site-specificity and kit therefor The invention relates to a method of determining the binding site specificity of an analyte to a ligand having at least two different binding sites, which method comprises immobilizing the ligand to a solid support, mixing the analyte with a reversibly binding refer... | 01/22/2008 |
| 7262866 | Analytical method and apparatus A method of examining thin layer structures on a surface for differences in respect of optical thickness, which method comprises the steps of: irradiating the surface with light so that the light is internally or externally reflected at the surface; imaging the refl... | 08/28/2007 |
| 7219528 | Sample flow positioning method and analytical system using the method A method of positioning a laminar flow of a sample fluid on a surface within a flow cell is disclosed. The method comprises providing a laminar flow of a first guiding fluid adjacent to a laminar flow of a second guiding fluid different from the first guiding fluid ... | 05/22/2007 |
| D528215 | Chip carrier for biosensor | 09/12/2006 |
| 7105356 | Method and device for laminar flow on a sensing surface Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods ... | 09/12/2006 |
| 7081958 | Analytical method and apparatus A method of examining thin layer structures on a surface for differences in respect of optical thickness, which method comprises the steps of: irradiating the surface with light so that the light is internally or externally reflected at the surface; imaging the refl... | 07/25/2006 |
| 7015043 | Flow cell method A method of operating an analytical flow cell device comprising an elongate flow cell having a first end and a second end, at least two ports at the first end and at least one port at the second end, comprises introducing a laminar flow of a first fluid at the first... | 03/21/2006 |
| 7012694 | Apparatus and method for total internal reflection spectroscopy An optical apparatus for total internal reflection spectroscopy comprises: a transparent body having an internally reflective surface; at least one source of electromagnetic radiation for providing at least one beam of collimated electromagnetic radiation; optical s... | 03/14/2006 |
| 6999175 | Analytical method and apparatus A method of examining thin layer structures on a surface for differences in respect of optical thickness, which method comprises the steps of: irradiating the surface with light so that the light is internally or externally reflected at the surface; imaging the refl... | 02/14/2006 |
| 6988317 | Valve integrally associated with microfluidic liquid transport assembly The present invention discloses a valve integrally associated with a microfluidic transport assembly that is useful for regulating the flow of a liquid sample through an analytical instrument such as, for example, a biosensor. The valve integrally associated with a ... | 01/24/2006 |
| 6844201 | Method for capturing analytes eluted from surface-bound ligands Methods for capturing analytes associated with surface-bound ligands are disclosed. The methods involve eluting analytes from surface-bound ligands with a first liquid to generate free analytes, and capturing the free analytes with a solid capturing material within ... | 01/18/2005 |
| 6808938 | Method and apparatus for assaying a drug candidate to estimate a pharmacokinetic parameter associated therewith A method and apparatus for assaying a drug candidate with a biosensor having one or more sensing surface-bound biomolecules associated therewith are disclosed. The method comprises the steps of measuring the binding interaction between the drug candidate and the one... | 10/26/2004 |
| 6775003 | Apparatus and method for total internal reflection spectroscopy An optical apparatus for total internal reflection spectroscopy comprises: a transparent body having an internally reflective surface; at least one source of electromagnetic radiation for providing at least one beam of collimated electromagnetic radiation; optical s... | 08/10/2004 |
| 6714303 | Analytical method and apparatus A method of examining thin layer structures on a surface for differences in respect of optical thickness, which method comprises the steps of: irradiating the surface with light so that the light is internally or externally reflected at the surface; imaging the refl... | 03/30/2004 |
| 6698454 | Valve integrally associated with microfluidic liquid transport assembly The present invention discloses a valve integrally associated with a microfluidic transport assembly that is useful for regulating the flow of a liquid sample through an analytical instrument such as, for example, a biosensor. The valve integrally associa... | 03/02/2004 |
| 6589798 | Method and system for analyte determination The invention relates to methods, kits and systems for determining an analyte in a liquid sample as well as the use thereof for concentration analysis and screening purposes. In one method, a specific binding partner to the analyte is permitted to compete... | 07/08/2003 |
| 6503760 | Method for capturing analytes eluted from surface-bound ligands Methods for capturing analytes associated with surface-bound ligands are disclosed. The methods involve eluting analytes from surface-bound ligands with a first liquid to generate free analytes, and capturing the free analytes with a solid capturing mater... | 01/07/2003 |
| 6493097 | Analytical method and apparatus A method of examining thin layer structures on a surface for differences in respect of optical thickness, which method comprises the steps of: irradiating the surface with light so that the light is internally or externally reflected at the surface; imagi... | 12/10/2002 |
| 6289286 | Surface regeneration of biosensors and characterization of biomolecules associated therewith Surface regeneration of affinity biosensors and characterization of biomolecules associated therewith by multivariate technique employing cocktails of regeneration agents to optimize regeneration of biosensor surface and/or characterize biomolecules assoc... | 09/11/2001 |
| 6207381 | Method for nucleic acid analysis A method of determining the binding of an oligonucleotide probe to a test nucleic acid sequence comprises the steps of: (a) providing the test nucleic acid sequence in single-stranded form, (b) contacting the test nucleic acid sequence under hybridizing c... | 03/27/2001 |
| 6200814 | Method and device for laminar flow on a sensing surface Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. S... | 03/13/2001 |
| 6143513 | Method and kit for detecting betalactam-containing compounds Methods and kits are disclosed for detecting betalactam-containing compounds in a sample, and typically liquid products intended for human consumption such as milk. Betalactam-containing compounds include the class of betalactam antibiotics which may be p... | 11/07/2000 |
| 6008893 | Reversible-flow conduit system Systems and methods for reversibly and controllably flowing a first and second fluid adjacent to one or more discrete sensing surfaces of a biosensor are disclosed herein. The systems utilize a flow-cell conduit adapted to flow the first and second fluids... | 12/28/1999 |
| 5972612 | Surface-sensitive detection of hybridization at equilibrium A method of analysing nucleic acid sequences comprises measuring by surface sensitive detection technique the binding interaction between a first nucleic acid sequence and a second nucleic acid sequence, one of the first and second nucleic acid sequences ... | 10/26/1999 |
| 5922594 | Method of producing bilayer lipid membranes Methods are disclosed for producing a substrate surface supporting a continuous planar bilayer lipid membrane by covalently binding a plurality of micellar of vesicle liposomes, optionally comprising a membrane protein or other biologically active membran... | 07/13/1999 |
| 5641640 | Method of assaying for an analyte using surface plasmon resonance In a method of assaying for an analyte in a fluid sample, the presence of the analyte is detected by determining the resulting change in refractive index at a solid optical surface in contact with the sample, which change is caused by the analyte involvin... | 06/24/1997 |
