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| Number | Title | Issue Date |
| 8173142 | Pharmaceutical compositions of drugs and neutralized acidic polymers Pharmaceutical compositions comprised of low-solubility and/or acid-sensitive drugs and neutralized acidic polymers are disclosed. ... | 05/08/2012 |
| 8048452 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitor A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer. ... | 11/01/2011 |
| 8026286 | Pharmaceutical compositions providing enhanced drug concentrations A drug in a solubility-improved form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use environment relative to a control comprising the same amount of the sam... | 09/27/2011 |
| 7897175 | Dosage forms comprising a CETP inhibitors and an HMG-CoA reductase inhibitor A dosage form comprises (1) a solid amorphous dispersion comprising a cholesterol ester transfer protein inhibitor and an acidic concentration-enhancing polymer and (2) an HMG-CoA reductase inhibitor. The solid amorphous dispersion and the HMG-CoA reductase inhibito... | 03/01/2011 |
| 7887840 | Pharmaceutical compositions comprising drug and concentration-enhancing polymers A solubility-improved drug form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use environment relative to a control comprising the same amount of the same dru... | 02/15/2011 |
| 7780988 | Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles Homogeneous solid amorphous dispersions of drugs in concentration-enhancing polymers are formed in desirable larger particle sizes with minimal fines by using an atomizer and process conditions capable of producing droplets having an average diameter of at least 50 ... | 08/24/2010 |
| 7611630 | Method and device for evaluation of pharmaceutical compositions A membrane-permeation test for evaluating pharmaceutical compositions is described. The method comprises the following steps: (1) providing a microporous membrane having a plurality of pores, the membrane having a feed side and a permeate side, wherein the feed side... | 11/03/2009 |
| 7550158 | Controlled release by extrusion of solid amorphous dispersions of drugs Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the influx of water to the core so as to cause extrusion of a portion of th... | 06/23/2009 |
| 6986844 | Solvent-resistant microporous polybenzimidazole membranes and modules Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed. ... | 01/17/2006 |
| 6623639 | Solvent-resistant microporous polybenzimidazole membranes Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.... | 09/23/2003 |
| 6221319 | Plasma discharge reactors for the preparation of bioactive compounds Plasma discharge reactors of various designs are disclosed; the reactors are capable of synthesizing large numbers of bioactive compounds of great chemical diversity.... | 04/24/2001 |
| 6140012 | Bacteriorhodopsin preparations having increased information storage times Bacteriorhodopsin materials and matrices are crosslinked with each other to enhance optical data storage lifetimes.... | 10/31/2000 |
| 6136222 | Liquid absorbent solutions for separating nitrogen from natural gas Nitrogen-absorbing and -desorbing compositions, novel ligands and transition metal complexes, and methods of using the same, which are useful for the selective separation of nitrogen from other gases, especially natural gas.... | 10/24/2000 |
| 6077457 | Liquid absorbent solutions for separating nitrogen from natural gas Nitrogen-absorbing and -desorbing compositions, novel ligands and transition metal complexes, and methods of using the same, which are useful for the selective separation of nitrogen from other gases, especially natural gas.... | 06/20/2000 |
| 6059857 | Ultrapurification of organic solvents A system for the ultrapurification of organic solvents comprising (1) a membrane-based vapor permeation step for selective removal of water vapor from the solvent, wherein a countercurrent sweep stream is used that has a particular partial pressure of wat... | 05/09/2000 |
| 5916983 | Biologically active compounds by catalytic olefin metathesis Biologically active compounds such as pheromones and precursors thereof are produced by catalyzed cross metathesis of dissimilar terminal olefins or of a cyclodiene and a terminal olefin.... | 06/29/1999 |
| 5888930 | Asymmetric microporous beads for controlled release A durable and sprayable controlled release bead of active ingredient in the pores of a polymeric micro-porous bead having an anisotropic pore structure of large pores in the interior and small pores at the surface, the gradation of pore sizes between the ... | 03/30/1999 |
| 5843209 | Vapor permeation system Membrane-based vapor permeation system for selective removal of a vapor from a fluid feed stream, wherein a countercurrent sweep stream is used that has a particular partial pressure of the vapor to be removed.... | 12/01/1998 |
| 5772855 | Preparation of bioactive compounds by plasma synthesis Large numbers of bioactive compounds of great chemical diversity may be rapidly prepared by subjecting organic compound mixtures to a plasma discharge, followed by screening for specific bioactivity.... | 06/30/1998 |
| 5753008 | Solvent resistant hollow fiber vapor permeation membranes and modules A vapor permeation method and apparatus for removing a vapor from a vaporous feed stream, the method and apparatus utilizing highly solvent-resistant composite hollow fiber membranes and a permeate flow countercurrent to the feed flow, wherein the support... | 05/19/1998 |
| 5750126 | Labile insecticide compositions There is disclosed a pesticidal composition comprising a pH-sensitive non-lignin-based polymer encapsulating both the active agent and a lignin-based UV screening agent.... | 05/12/1998 |
| 5725769 | Solvent-resistant microporous polymide membranes An asymmetric microporous membrane with exceptional solvent resistance and highly desirable permeability is disclosed. The membrane is made by a solution-casting or solution-spinning process from a copolyamic acid comprising the condensation reaction prod... | 03/10/1998 |
| 5726344 | Enantiomeric enrichment of bicyclic alcohols There is disclosed a two-stage enzymatically catalyzed reaction for the selective preparation of the (R)-endo-isomer of norbornenol from a mixture containing all four stereo- and regioisomers of norbornenol, as well as the synthesis of the intermediate pr... | 03/10/1998 |
| 5681433 | Membrane dehydration of vaporous feeds by countercurrent condensable sweep A process for the dehydration of a vaporous mixture. The basic process involves directing a predominantly condensable water vapor-containing vaporous mixture against the feed side of a membrane while maintaining the feed near saturation without condensing... | 10/28/1997 |
| 5645626 | Composite hydrogen separation element and module There are disclosed improvements in multicomponent composite metal membranes useful for the separation of hydrogen, the improvements comprising the provision of at least one common-axis hole through all components of the composite membrane and the provisi... | 07/08/1997 |
| 5611842 | Organic and inorganic vapor permeation by countercurrent condensable sweep A process for the removal of at least one non-water vapor component of a vaporous mixture, the basic process comprising directing a vaporous mixture against the feed side of a membrane, directing a condensable vapor sweep stream past the permeate side of ... | 03/18/1997 |
| 5582725 | Chlorine-resistant composite membranes with high organic rejection A method for making a chlorine-resistant composite polyamide membrane having high organic rejection, the essential step of which comprises treating a conventional composite membrane with an acyl halide. The novel membrane is especially suitable for the tr... | 12/10/1996 |
| 5516745 | Nitrogen sorption Nitrogen-sorbing and -desorbing compositions and methods of using the same are disclosed, which are useful for the selective separation of nitrogen from other gases, especially natural gas.... | 05/14/1996 |
| 5514276 | Permselective hollow fiber fluid separation membranes having plasma-polymerized lumen-side coatings Hollow fiber fluid separation membranes having a first lumen-side permselective coating and a second lumen-side plasma-polymerized coating are disclosed, as well as methods of making the same.... | 05/07/1996 |
| 5498278 | Composite hydrogen separation element and module There are disclosed improvements in multicomponent composite metal membranes useful for the separation of hydrogen, the improvements comprising the provision of a flexible porous intermediate layer between a support layer and a nonporous hydrogen-permeabl... | 03/12/1996 |
| 5494989 | Acetylenic copolymers and membranes thereof Acetylenic copolymers especially suitable for fabrication of gas and vapor separation membranes are disclosed.... | 02/27/1996 |
| 5464540 | Pervaporation by countercurrent condensable sweep There is described a process for the removal of at least one component of a liquid mixture, the basic process comprising directing a liquid mixture against the feed side of a membrane, directing a condensable vapor sweep stream past the permeate side of t... | 11/07/1995 |
| 5392559 | Surfaces coated with fluorocarbon resins upon which insects cannot climb or alight and methods and means for their establishment A dispersion of a polytetrafluoroethylene resin having a particle size between about 0.05 and 0.5 microns, a suspending agent and a viscosity less than 15 centipoise. The dispersion has long shelf life, a reduced tendency to fibrillate and is comparativel... | 02/28/1995 |
| 5393325 | Composite hydrogen separation metal membrane Composite hydrogen separation metal membranes are disclosed that contain an intermediate layer separating a base metal and a coating metal, wherein the intermediate layer is not a pure metal or metal alloy and is thermodynamically stable at operating temp... | 02/28/1995 |
| 5354469 | Layered plasma polymer composite membranes Layered plasma polymer composite fluid separation membranes are disclosed, which comprise alternating selective and permeable layers for a total of at least 2n layers, where n is ࣙ2 and is the number of selective layers.... | 10/11/1994 |
| 5288916 | Enantiomeric resolution of 4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone There is disclosed a method of separating enantiomers of 4-(3',4'-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenone comprising contacting the same with a homogeneous or nonhomogeneous liquid mixture of solvent and water, the mixture containing substantially... | 02/22/1994 |
| 5266283 | Sterically hindered, regenerable Schiff base complexes, solutions thereof and process using the same There are disclosed saltmen-type metallo Schiff base complexes and oxygen-sorbing and -desorbing solutions of the same, pressure- and temperature-swing oxygen separation processes using the complexes and solutions, and methods of regenerating such complex... | 11/30/1993 |
| 5263409 | Membrane extraction of citrus bittering agents There are disclosed two types of apparatus using membrane extractions of citrus juice bittering agents, both using extraction fluids. In one type, a membrane contactor facilitates contact between bittering agents present in a citrus juice feed and a hydro... | 11/23/1993 |
| 5259870 | Hydrogen-permeable composite metal membrane Novel composite metal membranes are disclosed that contain an intermetallic diffusion barrier separating a hydrogen-permeable base metal and a hydrogen-permeable coating metal.... | 11/09/1993 |
| 5241087 | Enantiomeric enrichment of cyanohydrins A method of enantiomerically enriching chiral cyanohydrins is disclosed that involves selective cleavage of the unwanted enantiomer into its cleavage products HCN and the corresponding aldehyde or ketone by use of an enantioselective dehydrocyanation cata... | 08/31/1993 |
