Did You Know...
...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Number | Title | Issue Date |
| 6162631 | Retrovirus from the HIV group and its use (MVP-2901/94) A novel immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 95012601. The characteristic antigens which can be obtained from the vi... | 12/19/2000 |
| 6020461 | Hexapeptides of Neisseria gonorrhoeae A nucleotide sequence characteristic of Neisseria gonorrhoeae is disclosed. The sequence can be the basis for hybridization type, nucleic acid-based, rapid, in vitro diagnostic assays. The unique nature of the sequence makes it possible to clearly discrim... | 02/01/2000 |
| 5981697 | Synthetic peptides, antibodies against them and their use The present invention is directed to the generation of antibodies which preferentially bind to fibrinogen fragments E1, E2, and E3, but exhibit little or no cross-reactivity against fibrin monomer and fibrinogen. Thus, the invention provides synthetic pep... | 11/09/1999 |
| 5959083 | Tetravalent bispecific receptors, the preparation and use thereof The invention relates to bispecific tetravalent receptors of the formula I ##STR1## or formula II ##STR2## against a tumor-associated antigen and against an agent active against tumors.... | 09/28/1999 |
| 5955100 | Prodrugs their preparation and use as pharmaceuticals Glycosyl-spacer-drugs compounds (prodrugs), their preparation and their use as pharmaceuticals are described.... | 09/21/1999 |
| 5902740 | Process for the decontamination of cell cultures containing mycoplasmas The invention relates to a process for the decontamination of cell cultures containing mycoplasmas. In this process the cell cultures infected by mycoplasmas undergo an antibiotic treatment in a first step, and cells still infected are then eliminated by ... | 05/11/1999 |
| 5892144 | Biosensor A biosensor (10) for measuring changes in viscosity, density and/or mass in a fluid to be examined, for example a blood coagulation sensor or immunoassay system. According to the invention, the reagents necessary for the test are contained in a support (1... | 04/06/1999 |
| 5883256 | Process for removing aromatic heterocyclic compounds product-containing solutions A process for removing aromatic heterocyclic compounds from a product-containing solution, in particular a protein solution, by bringing the solution into contact with a support material. The process is preferably carried out following a virus inactivatio... | 03/16/1999 |
| 5882924 | Vectors for the genetic selection of ligand binding proteins in microorganisms by means of signal transduction The invention relates to a process for the genetic selection in microorganisms of proteins which are capable of ligand binding, in which process a protein which is capable of ligand binding is presented extracytoplasmically and the signal of the ligand bi... | 03/16/1999 |
| 5877158 | Pro-prodrugs, their production and use Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.... | 03/02/1999 |
| 5859185 | HCMV-specific peptides, agents therefor and the use thereof The invention relates to peptides for the immunochemical determination of human cytomegalovirus (HCMV)-specific antibodies and HCMV antigens, and to agents suitable for this method and to the use thereof.... | 01/12/1999 |
| 5849799 | Use of deoxyspergualin for preparing a pharmaceutical for treating hyperreactive inflammatory diseases Methods are disclosed for treatment of hyperreactive inflammatory diseases of humans and animals comprising administering a pharmaceutically effective amount of deoxyspergualin to a human or an animal.... | 12/15/1998 |
| 5830638 | Cell line and processes for the replicating rabies viruses and detecting them quantitatively A permanent cell line PH2, and a process for replication of rabies viruses which have a cytopathic effect (CPE) is claimed. The process comprises: infecting the PH2 cell line with the virus to be replicated; incubating the cells; and isolating and purifyi... | 11/03/1998 |
| 5804430 | Bovine ovary cell line (FROV) for virus replication A bovine ovary cell line (FROv), a process for its preparation, and its use for replicating viruses, are described.... | 09/08/1998 |
| 5798205 | Retrovirus from the HIV type O and its use (MVP-2901/94) A novel HIV type O immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 95012601. The characteristic antigens which can be obtained ... | 08/25/1998 |
| 5743312 | Component mixing apparatus and system including a movable cannula An apparatus for combining liquid or solid components stored in containers includes a cylindrical hollow body for receiving end closures of the containers and at least one cannula for penetrating the end closures. The cannula is mounted in a cannula holde... | 04/28/1998 |
| 5744298 | DNA sequences which encode immunoreactive HCMV-specific peptides The invention relates to a DNA sequence which encodes three specific human cytomegalovirus (HCMV) peptides of the pp150 protein. These peptides are shown to have novel immunogenic properties. The DNA sequence is also used in a method of hybridization for ... | 04/28/1998 |
| 5731178 | Attachment-elements for stimulation of eukaryotic expression systems The invention concerns methods to increase the expression of genes brought into eukaryotic cells or organisms. By flanking a transcription unit EPC made up by e.g. an enhancer (E), promoter (P), and the (structural) gene of interest (C) with attachment-el... | 03/24/1998 |
| 5723123 | Process for the production of a virus-free concentrate of thrombin The invention relates to a process for producing a virus free preparation of thrombin, and the use of said virus free concentrate as a pharmaceutical. For example, the invention relates to a process for the production of a purified and virus free preparat... | 03/03/1998 |
| 5718898 | Saccharomyces-specific antigens and antibodies, their preparation and use Antibodies which are specific for Saccharomyces cerevisiae, Saccharomyces bayanus, Saccharomyces paradoxus and Saccharomyces pastorianus, and epitopes to which such antibodies bind are described. Diagnostic agents and assays for detecting Saccharomyces se... | 02/17/1998 |
| 5712370 | Erythropoietin (EPO) peptides and antibodies directed against these Erythropoietin (EPO) peptides and the use thereof for preparing epitope-specific anti-EPO antibodies are described. Also described are corresponding anti-EPO antibodies which take the form of polyclonal antibodies (antisera) or of monoclonal antibodies. T... | 01/27/1998 |
| 5710134 | Combination of necrosis-inducing substances with substances which are activated by necroses for the selective therapy of tumors and inflammatory disorders The invention relates to a combination of substances (component I) inducing necrosis in tumors or inflamed tissue with other nontoxic substances ("prodrugs", component II). The enzymes set free by necrotic processes then cleave the nontoxic "prodrug" into... | 01/20/1998 |
| 5700663 | Mutants of human antithrobin III and methods for their production Mutants of AT III which have been advantageously modified at one or more potential glycosylation sites or at the Arg393 position are described. As a rule, combination of the mutations enhances the advantageous modifications.... | 12/23/1997 |
| 5695758 | Monoclonal antibodies against tumor-associated antigens, processes for the preparation thereof and the use thereof The invention relates to monoclonal antibodies against a tumor-associated antigen which is mainly derived from tumors from the group of carcinomas of the breast, ovaries and prostate, as well as adenocarcinomas of the lung, which additionally react with p... | 12/09/1997 |
| 5695753 | Transglutaminases as immunosuppressants A description is given of the possibility of using transglutaminases in a process for the preparation of an immunosuppressant. Additionally described is a pharmaceutical containing a transglutaminase and a plasminogen activator inhibitor.... | 12/09/1997 |
| 5696001 | Fluorogenic compounds and their use The invention relates to fluorogenic compounds for the detection of hydrolyzing enzymes and the use of the fluorogenic compounds.... | 12/09/1997 |
| 5691312 | Pharmaceutical for subcutaneous or intramuscular administration containing polypeptides Liquid pharmaceuticals for subcutaneous (sc) or intramuscular (im) administration containing a polypeptide and at least one amino acid, a process for the preparation of such a pharmaceutical and the use of an amino acid, which is suitable for sc or im adm... | 11/25/1997 |
| 5688919 | Process for the purification of factor XIII, monoclonal antibodies against factor XIIIA, the preparation and use thereof A process for the purification of factor XIII or XIIIA by immunoaffinity chromatography, monoclonal antibodies against factor XIIIA, the preparation thereof and the use thereof are described.... | 11/18/1997 |
| 5686583 | Specific antibodies against activated platelets, the preparation thereof and the use thereof in diagnosis and therapy The invention relates to monoclonal antibodies and parts thereof which bind preferentially to active human platelets, to the nucleotide sequence and amino-acid sequence of the heavy and light chain of MAb BW 2128 and to an antigen associated with thrombos... | 11/11/1997 |
| 5683656 | Decreased interference redox detection device The present invention relates to reagents and processes for the preparation of diagnostics which use a chromogenic redox detection system and whose chromogenic redox detection system essentially remains unaffected by interference from reducing compounds i... | 11/04/1997 |
| 5674994 | Polynucleotides encoding the anti-PEM antibody BW835 variable domains and expression vectors The invention relates to polynucleotides encoding the BW 835 variable domain of an antibody against a tumor-associated antigen which is mainly derived from tumors from the group of carcinomas of the breast, ovaries and prostate, as well as adenocarcinomas... | 10/07/1997 |
| 5672687 | Magnetic protein conjugates, a process for the preparation thereof, and the use thereof The invention relates to magnetic protein conjugates of the formula I ##STR1## in which M represents a dispersible magnetically reacting material or particle which carries aminogroups, Ig represents a protein which carries one or more mercapto groups... | 09/30/1997 |
| 5670352 | Stable growth transformation of human T-lymphocytes by Herpesvirus saimiri (H. saimiri) subgroup C The invention concerns the transformation of human T-lymphocytes to stable growth by infecting said T-cells with strains of H. saimiri subgroup NonA NonB, preferably subgroup C. The transformed cells grow independently of antigen stimulation and can have ... | 09/23/1997 |
| 5665533 | Skin test to human papillomavirus type 16 The invention relates to a skin test to human papillomavirus (HPV) type 16.... | 09/09/1997 |
| 5663061 | Expression vectors for the synthesis of proteins in the fission yeast schizosaccharomyces pombe Particularly suitable expression vectors for the synthesis of proteins in the fission yeast Schizosaccharomyces pombe (S. pombe) are described. These expression vectors are (in addition to other advantageous elements, equipped with a strong homologous pro... | 09/02/1997 |
| 5656475 | Use of lymphocytes transformed with herpesvirus saimiri in a process for replicating viruses of the HIV type which cause immune deficiency A process is disclosed for replicating viruses of the HIV type which cause immune deficiency, in which process lymphocytes are employed which have been transformed with herpesvirus saimiri.... | 08/12/1997 |
| 5648229 | Fluorogenic compounds and their use The invention relates to fluorogenic compounds for the detection of hydrolyzing enzymes and the use of the fluorogenic compounds.... | 07/15/1997 |
| 5645817 | Granulocyte-binding antibody constructs, their preparation and use The present invention describes granulocyte-binding antibody constructs, which were derived from the monoclonal mouse antibody MAk BW 250/183 (EP-A1-0 388 914), as well as a process for their preparation and their use.... | 07/08/1997 |
| 5643731 | Use of pairs of leucine zipper peptides in immunoassay methods The invention relates to a method of using a pair of leucine zipper peptides for in vitro diagnosis, in particular, for the immunochemical detection and determination of an analyte in a biological liquid. In one method, the first leucine zipper peptide is... | 07/01/1997 |
| 5641638 | Monoclonal antibodies against Mycoplasma pneumoniae, hybridomas producing these, methods for the preparation thereof, and the use thereof The invention relates to monoclonal antibodies and fragments thereof which are specific for Mycoplasma pneumoniae P2 protein and have a cross-reactivity of 1% or less with five other species of the genus Mycoplasma and other pathogen species of the concom... | 06/24/1997 |
