Assignee: Beecham Group p.l.c. (GB2)

Location: Not specified.
No. of patents: 117

Browse patents
Browse applications

Number	Title	Issue Date
5066670	Macrolide derivatives with parasiticidal activity Compounds of formula (I): ##STR1## wherein R1 is methoxy or optionally protected hydroxy have anthelmintic activity and are useful in the treatment of helminthiasis in humans and animals....	11/19/1991
4863915	ଲ-lactam antibiotics Crystalline anhydrous amoxycillin is prepared by removing bound solvent molecules from a crystalline solvate (other than the trihydrate) of amoxycillin. A preferred crystalline solvate is the monomethanolate....	09/05/1989
4847242	11-ether derivatives of erythromycins 11-ether derivatives of erythromycin, and corresponding 9-(optionally substituted)-amino, 9-imino, and 9-(optionally substituted)-oxime derivatives are novel antibacterially active compounds, and can be prepared by alkylation of the 11-hydroxy group under...	07/11/1989
4842164	Striped paste dispenser A nozzle insert for a nozzle of a striped paste dispenser has a hollow cylindrical body through which a first pasty material may be dispensed, the external surface of the hollow body having circumferentially spaced apart plateaus separated by grooves thro...	06/27/1989
4835150	Cephem compounds ଲ-Lactam antibiotics are disclosed which have the formula (IA) or pharmaceutically acceptable salts or pharmaceutically acceptable in vivo hydrolyzable esters thereof: ##STR1## wherein R1 is phenyl, 3-hydroxyphenyl, 4-hydroxyphenyl, ...	05/30/1989
4831050	Pyrrolidinyl benzopyrans as hypotensive agents Compounds of formula (I): ##STR1## wherein: either one of R1 and R2 is hydrogen and the other is selected from the class of C1-6 alkylcarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyloxy, C1...	05/16/1989
4826820	6-carbamade erythromycin derivatives Antibacterially active 6-carbamate erythromycin derivatives of formula I and their pharmaceutically acceptable esters and acid addition salts; ##STR1## wherein: R1 or R2 is optionally substituted amino, or R1 or R	05/02/1989
4820701	Penam derivatives Antibacterial agents have the formula (I) or are pharmaceutically acceptable salts or in vivo hydrolysable esters thereof: ##STR1## wherein R3 is phenyl, substituted phenyl, cyclohexenyl, cyclohexadienyl or an optionally substituted 5- or ...	04/11/1989
4812470	Antibacterial monic acid derivatives A compound of the formula (I) ##STR1## wherein R is a group ##STR2## R1 is hydrogen, phenyl, C1-20 alkyl, C2-8 alkenyl or C2-8 alkynyl each of which may optionally be substituted; or C3-7	03/14/1989
4812459	Anti-hypertensive pyranopyridine compounds A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein all the symbols are defined in the specification; having pharmacological activity, including blood pressure lowering activity, a process and intermediates for t...	03/14/1989
4808405	P-anisoyl streptokinase/plasminogen complex A binary complex between streptokinase and plasminogen is prepared in which the catalytic site essential for fibrinolytic activity is blocked by a group which is removable by hydrolysis such that the pseudo-first order rate constant for hydrolysis of the ...	02/28/1989
4808619	Di/tetra-hydroquinolines Compounds of the formula ##STR1## as defined in the specification, and processes for their preparation and methods of using the compounds for the treatment of hypertension in mammals, such as humans and for the treatment and/or prophylaxis of ce...	02/28/1989
4800212	Pyrrolidone-2 compounds and anti-hypertensive use thereof Compounds of formula (I) or when a compound of formula (I) contain a salifiable group, a pharmaceutically acceptable salt thereof: ##STR1## wherein: R1 -R7 and X are as defined, are useful as anti-hypertensive agents....	01/24/1989
4790989	Treatment of fungal infections Certain formulations of pseudomonic acids and their salts have good antifungal activity....	12/13/1988
4789679	Method for treating incontinence A method for the treatment and/or prophylaxis of incontinence in mammals, which method comprises administering to the mammal an effective amount of the compound pinacidil or a pharmaceutically acceptable salt or solvate thereof....	12/06/1988
4786639	Method for the treatment of reversible airways obstruction and asthma A method for the treatment and/or prophylaxis of reversible airways obstruction and asthma in mammals, which method comprises administering to the mammal in need of said treatment an effective amount of a compound of formula (I): ##STR1## wherei...	11/22/1988
4786742	Crystalline lithium pseudomonete This invention relates to a novel salt of an antibacterial compound and to a process for its preparation....	11/22/1988
4772603	Method for treating congestive heart failure, angina, occlusive peripheral vascular disease or cerebral vascular disease in mammals A method for the treatment and/or prophylaxis of congestive heart failure, angina, occlusive peripheral vascular disease or cerebral vascular disease in mammals, such as humans, which method comprises administering to the mammal in need of such treatment ...	09/20/1988
4769383	Dioxonaphthotriazoles having antiallergic activity A compound of formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, wherein R1 is a hydrogen atom or a C1-6 alkyl group, R2, R3 and R4 are the same or different and are selected fr...	09/06/1988
4767751	Topical drug release system A pharmaceutical composition for topical administration consisting of two liquid phases designed to be admixed in situ or prior to use. The first phase contains a dissolved drug, and is preferably saturated in the drug, while the second phase is a chemica...	08/30/1988
4762847	Method of treating acne A topical composition for application to skin affected by acne containing from 0.05 to 2% by weight of Octopirox together with a non-irritant topically acceptable carrier. The composition is particularly useful for treating acne vulgaris....	08/09/1988
4753962	Secondary amines, their preparation and use in pharmaceutical compositions The compounds of the formula (II): ##STR1## and their pharmaceutically acceptable salts wherein R1 is a hydrogen, fluorine or chlorine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, ...	06/28/1988
4752581	Novel compounds A fibrinolytically active hybrid protein which comprises one chain of a 2-chain protease linked to a chain of a different 2-chain protease, or to the same chain of the same protease, at least one of the chains in the hybrid protein being derived from a fi...	06/21/1988
4743593	9,11-O-methylene derivatives of 9-dihydroerythromycin An antibacterially active 9,11-O-methylene derivative of 9-dihydroerythromycin wherein the methylene group is optionally substituted by one or two hydrocarbon groups. In particular, compounds of formula I and their pharmaceutically acceptable esters and a...	05/10/1988
4741903	Novel enzyne derivatives A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by a human protein attached thereto by way of a reversible linking group....	05/03/1988
4738963	Method for the treatment of incontinence in mammals A method for the treatment and/or prophylaxis of incontinence in mammals, which method comprises administering to the mammal in need of said treatment an effective amount of a compound of formula (I): ##STR1## wherein R1 -R8 and...	04/19/1988
4732901	Certain pyridyl, thienyl or furyl propenoic acids or esters having anti-inflammatory anti-allergic properties Compounds of formula (I): ##STR1## in which R1 is hydrogen or C1-6 alkyl; R2 is hydrogen or a group --CO2 R3 where R3 is hydrogen or C1-6 alkyl; n is an integer of from 2 to 12; ...	03/22/1988
4730050	Novel enzyme derivatives A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by a human protein attached thereto by way of a reversible linking group....	03/08/1988
4707474	Veterinary composition of cloxacillin for eye treatment Compositions comprising a cloxacillin salt and liquid paraffin, arachis oil or fractionated coconut oil are useful in treating infectious keratoconjunctivitis in cattle and domestic animals....	11/17/1987
4705858	Azabicyclo[3.3.1]nonanes Certain endo-9-lower-alkyl 9-azabicyclo[3.3.1]nonane-3-amines are valuable intermediates for the preparation of 2-methoxy-4-amino-5-halo-N-[9-lower-alkyl]-azabicyclo[3.3.1]nonanylbenzami des wherein said final products possess useful pharmacological activi...	11/10/1987
4704385	3-formamido azetidinone antibacterial agents, their preparation and use A monocyclic ଲ-lactam antibiotic having a formamido substituent at the 3S-position, including compounds of the formula (I): ##STR1## and salts thereof wherein R is --SO3 H; --PO(OH)Y wherein Y is C1-6 alkoxy, hydroxy, aryl...	11/03/1987
4687779	Chromanol derivatives Compounds of formula (I): ##STR1## wherein: either one of R1 and R2 is hydrogen and the other is selected from C1-6 alkylcarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyloxy, C1-6 alk...	08/18/1987
4678102	Container having a hooked-shaped member slidably attached thereto A container (1) for dispensing viscous liquids consists of a hollow, resilient oval body (2) having a valve cap (6), and a hook-shaped support (7) slidably attached to the body (2). The support (7) may be fully extended and the hook (9) used to suspend th...	07/07/1987
4678782	3S-formamido azetidinone antibacterial agents, their preparation and use A monocyclic ଲ-lactam antibiotic having a formamido substitutent at the 3S-position, including compounds of the formula (I): ##STR1## and salts thereof wherein R is --SO3 H; --PO(OH)Y wherein Y is C1-6 alkoxy, hydroxy, ary...	07/07/1987
4677116	Antihypertensive chroman derivatives Compounds of formula (I) ##STR1## wherein: either one of R1 and R2 is hydrogen and the other is selected from the class of C1-6 alkylcarbonyl, C1-6 alkoxycarbonyl, C1-6 alkylcarbonyloxy, C1-...	06/30/1987
4673573	Novel fibrinolytic enzyme compounds A fibrinolytically active protein conjugate comprising at least one optionally blocked fibrinolytic enzyme linked by way of a site other than the catalytic site responsible for fibrinolytic activity to at least one human protein. Processes from making the...	06/16/1987
4670431	Beta-lactam antibacterial agents A compound having the partial structure (A): ##STR1## wherein n is 1 or 2....	06/02/1987
4665072	Morpholine derivatives, compositions and method of use Compounds of formula (I): ##STR1## or a salt thereof, in which W is phenyl optionally substituted by halogen or trifluoromethyl, or a benzofuran-2-yl group, R1 is hydrogen or methyl, R2 is carboxyl or a group O--Z--CO2 H o...	05/12/1987
4661489	Benzazepines, and their use as anthelminthics A compound of formula (I): ##STR1## in which R is optionally substituted phenyl; C3-8 cycloalkyl; C5-8 cycloalkenyl; C1-8 alkyl which may be straight or branched; C2-8 alkenyl which may be straight or branc...	04/28/1987
4661480	Formamido oxacephems A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolyzable ester thereof: ##STR1## R is phenyl, substituted phenyl, C3-6 cycloalkyl cyclohexenyl, cyclohexadienyl, or a 5- or 6-membered heterocyclic ring contain...	04/28/1987

«First «Previous1 2 3 Next»Last»

PatentStorm

Bizarre Patents

PatentStorm News

Assignee: Beecham Group p.l.c. (GB2)