Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 8183233 | Stable pharmaceutical formulations Stable pharmaceutical formulations and methods of making same are provided. In a general embodiment, the present disclosure provides a method of making a stable pharmaceutical formulation comprising adding one or more vitrifying additives to an aqueous pharmaceutica... | 05/22/2012 |
| 8182673 | Drain and fill logic for automated peritoneal dialysis A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments... | 05/22/2012 |
| 8182445 | Method and system for controlled infusion of therapeutic substances Programmable infusion systems and method for controlled infusion of diagnostic or therapeutic substances (e.g., drugs, biologics, fluids, cell preparations, etc.) into the bodies of human or animal subjects. ... | 05/22/2012 |
| 8182440 | Dialysis machine having combination display and handle The present invention provides a dialysis machine that is readily moved by a patient, nurse or other operator. A display is provided on the front of the machine, which displays and controls various dialysis functions. The display is robust, mounted directly to the b... | 05/22/2012 |
| 8178121 | Ready-to-use paracetamol injection solutions containing propylene glycol as the only cosolvent The present invention refers to ready-to-use highly stable paracetamol injectable solutions, prepared by mixing paracetamol, water, propylene glycol, and a citrate buffer. (pH 4.5 to 6.5), and by heating said solution under preset conditions. The resulting solution ... | 05/15/2012 |
| 8178120 | Methods for processing substrates having an antimicrobial coating Methods for processing substrate surfaces carrying coatings comprising a metal are disclosed. The methods involve providing a substrate surface having a coating comprising a metal, and exposing the substrate surface to a mixture including an oxidizing agent and an a... | 05/15/2012 |
| 8173597 | Modified recombinant factor VIII and von Willebrand factor and methods of use The present invention provides novel methods of increasing the survival of a coagulation protein by inhibiting the interaction with a clearance receptor. The invention also provides methods of preparing compositions that inhibit coagulation protein clearance recepto... | 05/08/2012 |
| 8172823 | Port assembly for use with needleless connector A port assembly includes a valve housing with an inlet opening, a valve disposed in the valve housing to control access through the inlet opening, and a base joined to the valve housing and having a bore therethrough. The bore has a closed end defined by a frangible... | 05/08/2012 |
| 8168063 | Dialysis system having filtering method for determining therapy prescriptions A peritoneal dialysis system includes a logic implementer configured to: (i) generate a number of peritoneal dialysis therapy regimens that meet at least one therapy target input; (ii) accept a filter input; and (iii) filter the generated therapy regimens according ... | 05/01/2012 |
| 8167259 | Rapid attach and release clamps Rapid attach and release clamps for attaching to supports include a threaded rod, an arm pivotally attached to the threaded rod, and a knob having an exterior surface and an interior surface. The knob defines a passageway sized to fit the threaded rod. A lock compri... | 05/01/2012 |
| 8158341 | Efficient algorithm for PCR testing of blood samples A method is provided for identifying viral positive biological fluid donations in the fewest number of test cycles. The method comprises providing biological fluid donations and defining an n-dimensional matrix comprising a multiplicity of elements, each element bei... | 04/17/2012 |
| 8158157 | Multi-part substitution infusion fluids and matching anticoagulants A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solutio... | 04/17/2012 |
| 8157761 | Peritoneal dialysis patient connection system A peritoneal dialysis patient assist device includes (i) a port holder shaped to hold a first connector and a first plug, (ii) a transfer set holder shaped to hold a second connector and a second plug, the transfer set holder rotatable and translatable with respect ... | 04/17/2012 |
| 8152751 | Acoustic access disconnection systems and methods An access disconnection system includes: an arterial line; a venous line; a transmitter configured to transmit a sound wave in one of the arterial and venous lines when connected to a patient; a receiver configured to receive the sound wave from the other of the art... | 04/10/2012 |
| 8152116 | Dialysate bag seal breakage sensor incorporated in dialysate bag management A stand for a medical fluid treatment, a system for supporting medical fluid bags, and a method for testing and sensing whether a bag or a seal in a chamber of a multi-chamber bag has been broken prior to providing therapy. A stand stores one or more medical fluid b... | 04/10/2012 |
| 8148502 | R-ALPHA1 antitrypsin anion exchange chromatography The present invention relates to a method for obtaining highly purified recombinant alpha1-antitrypsin (rAAT) using anion exchange chromatography, wherein a composition comprising rAAT and at least one impurity originating from cultivation of cells used for generati... | 04/03/2012 |
| 8146642 | Apparatus and method for connecting and disconnecting flexible tubing A laser strikes and aseptically heats or sterilizes the end of two flexible tube ends for connection. Tube holders are pushed toward each other to bring the tube ends into contact. A weld detector checks the characteristics of the weld. A laser optics assembly may b... | 04/03/2012 |
| 8143347 | Pegylation of recombinant blood coagulation factors in the presence of bound antibodies The present invention relates to a proteinaceous construct comprising a blood coagulation factor, e.g., Factor VIII (FVIII), being bound to at least one water soluble polymer, including a poly(alkylene oxide) such as polyethylene glycol (PEG). Further the present in... | 03/27/2012 |
| 8142649 | Method for optimizing tidal therapies employing ultrafiltrate trending A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments... | 03/27/2012 |
| 8137300 | Access disconnection systems and methods using conductive contacts An extracorporeal blood system includes: an extracorporeal blood machine including an extracorporeal blood circuit; an access device enabling the extracorporeal blood circuit to be connected to a patient; first and second tube connecting members for connecting respe... | 03/20/2012 |
| 8137083 | Infusion pump actuators, system and method for controlling medical fluid flowrate An infusion pump includes an actuator having an output shaft; a pump actuator having a length (lactuator) moved by the output shaft and in contact with tubing, such that the pump actuator at an output shaft actuated distance (x) creates flat contact areas... | 03/20/2012 |
| 8133865 | von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided. ... | 03/13/2012 |
| 8129031 | Films containing microlayer structures Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides an autoclavable film containing a first microlayer of a heat resistant polymer and a second microlayer of a flexible polymer attached to the first microlaye... | 03/06/2012 |
| 8123947 | Priming and air removal systems and methods for dialysis A renal treatment fluid priming method includes priming an extracorporeal circuit connected to a patient with a physiologically compatible fluid, the extracorporeal circuit including an arterial line, a venous line and blood compartment of a blood filter; and pumpin... | 02/28/2012 |
| 8114633 | Methods for differentiating plasma-derived protein from recombinant protein in a sample The present invention relates, in general, to methods for detecting and quantitating plasma-derived protein and recombinant protein in a sample based on the difference in protein glycosylation, when the plasma protein and the recombinant protein are essentially the ... | 02/14/2012 |
| 8114276 | Personal hemodialysis system A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first an... | 02/14/2012 |
| 8114043 | Electromagnetic induction access disconnect sensor A connection of a patient's vascular system to an extracorporeal blood treatment machine is monitored to ensure the patient's safety during a procedure. The procedure may be hemodialysis, apheresis, plasmapheresis, a coronary by-pass operation, or other procedure. T... | 02/14/2012 |
| 8105269 | In situ tubing measurements for infusion pumps An infusion pump uses sensors and a computer program to detect tubing in a tube-loading section of the pump. The pump and the computer program also measures one or more of the tubing outer diameter, outer circumference, inner diameter, inner circumference, and tubin... | 01/31/2012 |
| 8105266 | Mobile dialysis system having supply container detection A dialysis system includes a dialysis instrument including at least one pump actuator; a disposable cassette operable with the at least one pump actuator; a plurality of supply containers connected fluidly to the disposable cassette; and a cart which includes a rota... | 01/31/2012 |
| 8105258 | Citrate anticoagulation system for extracorporeal blood treatments A hemofiltration system and method for pumping blood from a patient's blood stream into an access line, introducing an anticoagulant solution into the pumped blood, filtering the pumped blood and delivering it to a return line, introducing a substitution fluid into ... | 01/31/2012 |
| 8097346 | Barrier films containing microlayer structures Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides a film containing a first microlayer of a heat resistant polymer and a second microlayer of a barrier polymer having a heat distortion temperature ranging b... | 01/17/2012 |
| 8094307 | Method and apparatus for measuring the presence and concentration of pharmaceutical substances in a medical fluid administered by a medication delivery system Test equipment determines the contents of medical fluids to be delivered to a patient by a medication delivery system by measuring optical properties of the fluids. One system provides a non-invasive test that uses optical rotation caused by optically active pharmac... | 01/10/2012 |
| 8093230 | Supersaturated aqueous ifosfamide compositions The invention concerns the use of mercaptoethane sulfonate-sodium (Mesna) to increase the solubility of Ifosfamide in storage-stable, concentrated and/or highly-concentrated (supersaturated) aqueous pharmaceutical preparations, storage-stable, concentrated and/or hi... | 01/10/2012 |
| 8092820 | Dry hemostatic compositions and methods for their preparation Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain re-hydration aids, such as polyethylene glycol, polyvinylprovidone, and dextra... | 01/10/2012 |
| 8083709 | Dialysis method having supply container autoconnection A method for connecting a plurality of solution line connectors to a plurality of supply line connectors of a dialysis system includes: translating a tip protector remover in a first direction towards the plurality of supply line connectors to remove a plurality of ... | 12/27/2011 |
| 8083677 | Access disconnect detection using glucose An access disconnect sensor for a patient undergoing extracorporeal blood processing includes an electrochemical fuel cell or sensor to detect blood leakage. The fuel cell includes circuitry for oxidizing glucose in the blood. The sensor also includes a transmitter ... | 12/27/2011 |
| 8080161 | Dialysis treatment devices for removing urea Dialysis treatment devices and methods for removing urea from dialysis waste streams are provided. In a general embodiment, the present disclosure provides a dialysis treatment device including: 1) a first filter having a filtration membrane, 2) a urea removal unit ... | 12/20/2011 |
| 8080091 | Dialysis systems and methods including cassette with fluid heating and air removal A dialysis fluid system includes an instrument including a pump actuator and a fluid heater, and a dialysis fluid cassette. The dialysis fluid cassette includes a rigid portion defining a pumping section for operation with the pump actuator and a heating section for... | 12/20/2011 |
| 8078333 | Dialysis fluid heating algorithms A dialysis fluid heating system includes a dialysis fluid heater; a dialysis fluid carrying element in operable communication with the dialysis fluid heater to heat a dialysis fluid; and a logic implementer configured to control the heater using (i) a heater input d... | 12/13/2011 |
| 8075919 | Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation The present invention is related to a method for preparing small spherical particles of an active agent by providing a solution in a single liquid phase. The single liquid phase comprises an active agent, a phase separation enhancing agent, and a first solvent. A ph... | 12/13/2011 |
