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| Number | Title | Issue Date |
| 8183325 | Perfluorocyclobutane copolymers The present invention provides copolymer having repeating units based on polyoxyalkylene radicals, polysiloxane radicals and perfluorocyclobutane radicals. The copolymers are useful as biomedical devices such as contact lenses or intraocular lenses. ... | 05/22/2012 |
| 8173640 | Compositions and methods for treating, reducing, ameliorating, or preventing infections Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Su... | 05/08/2012 |
| 8162919 | Flow control system based on leakage An ophthalmic surgical system utilizes a needle through which fluid is aspirated from a surgical site, and a sleeve coaxially received over the needle to define a flow passage between the sleeve and needle through which fluid is communicated to the surgical site. Th... | 04/24/2012 |
| 8157378 | Eye illumination apparatus and method An ophthalmic apparatus adapted to project a waist of a beam of the light, such that a portion of the confocal region of the waist is projected onto the cornea. The source can be at least partially coherent and/or monochromatic. The source may be a laser or a laser ... | 04/17/2012 |
| 8138290 | High water content ophthalmic devices An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an eq... | 03/20/2012 |
| 8138288 | Synthesis of cationic siloxane prepolymers This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing t... | 03/20/2012 |
| 8138156 | Ophthalmic compositions containing diglycine Ophthalmic composition comprising one or more polyglycines selected from the group consisting of diglycine, triglycine, tetraglycine and pentaglycine, or the salts of each thereof and one or more boron buffering compounds. The ophthalmic composition will have an osm... | 03/20/2012 |
| 8133960 | Biomedical devices Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversibl... | 03/13/2012 |
| 8133512 | Drug delivery systems based on catonic siloxanyl macromonomers Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein. ... | 03/13/2012 |
| 8133511 | Drug delivery system based on cationic siloxanyl macromonomers Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are a... | 03/13/2012 |
| 8119753 | Silicone hydrogels with amino surface groups A silicone hydrogel comprising monomeric units of one or more amino monomers, wherein the amino monomers are of formula IA, IB, IIA or IIB and monomeric units of one or more silicone monomers wherei... | 02/21/2012 |
| 8119112 | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid Ophthalmic compositions that comprise 0.1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 0.15 wt. % of hyaluronic a... | 02/21/2012 |
| 8114420 | Composition for treating dry eye and related methods of manufacture and methods of use The present invention is directed to a composition for treating dry eye comprising, in one embodiment, carboxymethylcellulose and a polyol. Such compositions have been found to alleviate the symptoms of dry eye and remain in the eye for a long period of time. ... | 02/14/2012 |
| 8114095 | Intraocular lens injection apparatus and method An IOL injector comprising a distal body portion comprising a tip through which an IOL is injected into an eye, a tip protector, and a proximal body portion configured to connect to the distal body portion. The distal body portion and the tip protector being are con... | 02/14/2012 |
| 8105623 | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirabl... | 01/31/2012 |
| 8105070 | Apparatus and method for releasing a lens molded in a cavity between posterior and anterior mold sections An apparatus and method for releasing a lens moulded in a cavity between posterior (21) and anterior mould (22) sections and adhered thereto. A post (30) is configured to support a flange (20) of the posterior section whilst the anterior ... | 01/31/2012 |
| 8101698 | Surface active prepolymers with both fluorine-containing groups and hydrophilic groups Provided are surface modified contact lenses formed from one or more fumaric-or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers. ... | 01/24/2012 |
| 8100528 | Coating solutions comprising segmented interactive block copolymers This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reactin... | 01/24/2012 |
| 8092024 | Eye measurement apparatus and methods of using same An apparatus for measuring a subject's eye having an instrument axis, comprising a slit projector for projecting slits of light, at least one sensor. The apparatus being adapted to form a first image of light from a first slit on the at least one sensor after the li... | 01/10/2012 |
| 8085392 | Bubble reduction system An ophthalmic device forming system includes an inspection station configured to receive a plurality of ophthalmic devices, a fluid supply fluidly connected to the inspection station, the fluid supply containing a working fluid, and a heat source fluidly connected b... | 12/27/2011 |
| 8083348 | Biomedical devices Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization... | 12/27/2011 |
| 8071704 | Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to surface modifying polymers. ... | 12/06/2011 |
| 8071661 | Biomedical devices Biomedical devices are provided herein which are formed from a polymerization product of a mixture comprising (a) a copolymer which is the reaction product of one or more polymerizable polyhydric alcohols and one or more polymerizable fluorine-containing monomers; a... | 12/06/2011 |
| 8071660 | Surface modified biomedical devices A method for making a surface modified biomedical device is disclosed, the method comprising contacting a surface of a biomedical device with a copolymer which is the reaction product of one or more polymerizable polyhydric alcohols and one or more polymerizable flu... | 12/06/2011 |
| 8070475 | Casting mold for forming a biomedical device including an ophthalmic device A casting mold is provided for forming a biomedical device including an ophthalmic device such as a contact lens. The casting mold includes an anterior mold section and a posterior mold section, wherein one of the mold sections includes a plurality of radially exten... | 12/06/2011 |
| 8062360 | Intraocular lens injector and method An injector and method for injecting a dual optic AIOL into an eye wherein the AIOL is loaded into the injector in an initially loaded condition with the first and second optics in generally coaxial alignment. A lens moving element is provided and operable to move t... | 11/22/2011 |
| 8061216 | Aspiration flow mesurement system with flow signal air bubble filter In an aspiration flow measurement system, a flow channel is provided for receiving an aspiration fluid flow therethrough. The flow measurement system further includes an aspiration flow measurement chamber and a flow sensor that is configured to generate a raw signa... | 11/22/2011 |
| 8053489 | Crosslink agents and dual radical cure polymer Crosslink agents used to copolymerize at least one hydrophilic monomer with at least one lens monomer typically used to prepare polymeric materials for ophthalmic lenses. The crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited... | 11/08/2011 |
| 8043369 | Biomedical devices Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer comprising one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (RAFT) agent; a... | 10/25/2011 |
| 8038912 | Method and apparatus for the dry release of a compliant ophthalmic article from mold surface An apparatus for releasing a molded lens from a deformable mold includes a shear ring for temporarily retaining an annular portion of the deformable mold outside a periphery of the lens and a plunger for deforming an annular section of the deformable mold within the... | 10/18/2011 |
| 8035809 | Bubble removal system A bubble removal system includes an inspection cell configured to receive an ophthalmic device and a volume of working fluid. The system also includes a vacuum device configured to form a substantially fluid-tight seal with the inspection cell and to direct a negati... | 10/11/2011 |
| 8034813 | Polymorphs of brimonidine pamoate A brimonidine (5-bromo-6-(2-imidazolidinylideneamino)quinoxaline) pamoate polymorph exhibits characteristics disclosed herein. The brimonidine pamoate polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocu... | 10/11/2011 |
| 8034018 | Surgical system having means for stopping vacuum pump The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 24, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a hand... | 10/11/2011 |
| 7994356 | Mono ethylenically unsaturated polycarbosiloxane monomers The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form... | 08/09/2011 |
| 7988988 | Contact lenses with mucin affinity A biomedical device, such as a contact lens, has a surface linked to a polymer comprising boronic acid moieties. The boronic acid monomeric units may be derived from an ethylenically unsaturated monomer containing a boronic acid moiety, such as a vinylphenyl boronic... | 08/02/2011 |
| 7988701 | Preloaded IOL injector A preloaded intraocular lens injection device includes a retainer for releasably holding an IOL in an unstressed state. The retainer and IOL are removably attached to an injector body and are sealed in the same package for delivery to a surgeon. In an alternate embo... | 08/02/2011 |
| 7980698 | Power-adjusted aberrometer Aspects of the invention are directed to apparatus and methods for automatically setting a power level of light emitted by a light source; illuminating a retina of a patient with the light emitted by the light source; receiving, at a sensor, light reflected from the... | 07/19/2011 |
| 7960447 | Cationic end-capped siloxane prepolymer for reduced cross-link density The present invention relates to hydrophilic dicationic siloxane prepolymers with one polymerizable vinyl moiety instead of two polymerizable vinyl moieties, resulting in contact lenses and/or biomedical devices with reduced cross-link density and modulus without de... | 06/14/2011 |
| 7957059 | Device and method for demonstrating optical effects An optical system includes two lens systems, one that provides viewing of an object with relatively no spherical aberration, and another that provides viewing of the object with significant spherical aberration. Preferably, both lens systems provide viewing of the o... | 06/07/2011 |
| 7951897 | Synthesis of cationic siloxane prepolymers This application is directed toward an improved method of synthesizing cationic siloxane prepolymers as well as a specific cationic siloxane prepolymer having improved compatibility with monofunctional siloxanyl methacrylate monomers and medical devices containing t... | 05/31/2011 |
