Assignee: BTG International Limited

Location: London, GB
No. of patents: 171

Number	Title	Issue Date
8122917	Apparatus and method for dispensing foam A foam transfer device is described, for use with aerosol canister apparatus for producing a sclerosant foam for the treatment of, inter alia, varicose veins. The device enables diversion of an initial quantity of below-specification foam from the canister to waste,...	02/28/2012
8114903	Cytokine modulators using cyclic glycerides of essential polyunsaturated fatty acids A method of treating a patient in need of therapy for a cytokine dysregulation comprising administering to that patient a therapeutically effective dose of a compound of general formula: (I) wherein R1 and R2 together form a group —(CH2	02/14/2012
8101653	Therapeutic compositions Compositions comprising ketone bodies and/or their metabolic precursors are provided that are suitable for administration to humans and animals and which have the properties of, inter alia, (i) increasing cardiac efficiency, particularly efficiency in use of glucose...	01/24/2012
8091801	Generation of therapeutic microfoam Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, th...	01/10/2012
8076474	Methanesulfonate salts of abiraterone-3-esters and recovery of salts of abirater one-3-esters from solution in methyl tert-butyl ether A salt of a compound of formula (I) may be made with methanesulfonic acid. The salt and salts with other acids may be prepared by recovering from methyl tert-butyl ether (MTBE). ...	12/13/2011
8066776	Tibial component Prosthesis for implantation in the knee having a tibial component for attachment to the tibia. The tibial component has a first, upper surface and a second, lower surface opposite the first surface for attachment to the tibia. The first surface includes a lateral be...	11/29/2011
8063056	Anti-cancer cyclopenta []quinazonline compounds Cyclopenta[g]quinazolines of the formula (I):— wherein: A is a group OR or NR0R1 wherein R0 and R1 are each independently hydrogen C1-4	11/22/2011
8053432	Cyclic hydroxylamine as psychoactive compounds A compound of formula (I): in which X represents O or CH2; R3 and R4 each independently represent hydrogen or C1-6 alkyl; p represent 0 or 1; and R represents a five- or six-membered saturated or unsaturated ring selected ...	11/08/2011
7998943	Core 2 GlcNAc-T inhibitors III A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective amount of an inhibitor of core 2 GlcNAc-T of the formula I to a patie...	08/16/2011
7994289	Humanized anti-CD3 antibodies An IgG antibody is provided having a binding affinity for the CD3 antigen complex in which in the heavy chain has a variable region framework together with at least one CDR selected from the amino acid sequences of SEQ ID No 2, 4 and 6 and respective conservatively ...	08/09/2011
7993641	Methods of treatment using anti-CD3 antibodies An IgG antibody is provided having a binding affinity for the CD3 antigen complex in which in the heavy chain has a variable region framework together with at least one CDR selected from the amino acid sequences of SEQ ID No 2, 4 and 6 and respective conservatively ...	08/09/2011
7964641	Treatment of neurodegenerative conditions A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety ...	06/21/2011
7947736	Oligomeric compounds Method for the synthesis of a compound of formula H(OCH[CH3]CH2C[O])3—O-A-O—R wherein A is the residue of 1,3-butandiol and R is H or H(OCH[CH3]CH2C[O]3—. The method comprises reacting a cyclic ...	05/24/2011
7935729	Use of triglyceride oils containing γ-linolenic acid residues and linoleic acid residues for the treatment of neurodegenerative disease Method for treating a patient in need of therapy for a neurodegenerative disease by administering to that patient a therapeutically effective dose of a triglyceride oil containing both γ-linolenic acid and linolenic acid residues as triglyceride ester. The ratio of...	05/03/2011
7906493	Core 2 GlcNAc-T inhibitors Method of treating conditions associated with raised activity of core 2 GlcNAc-T by administering an inhibitor of UDP-GlcNAc:Galβ1,3GalNAc-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyl transferase (core 2 β1,6 N-acetylaminotransferase, core 2 GlcNAc-T-EC 2.4.1.1...	03/15/2011
7863284	Anti-cancer cyclopenta[G]quinazoline compounds Cyclopenta[g]quinazolines of the formula (I): —wherein: A is a group OR or NR0R1 wherein R0 and R1 are each independently hydrogen C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl, C2-4 ...	01/04/2011
7842690	Cyclic hydroxylamine as psychoactive compounds A compound of formula (I): in which X represents O or CH2; R3 and R4 each independently represent hydrogen or C1-6 alkyl; p represent 0 or 1; and R represents a five- or six-membered saturated or unsaturated ring selected ...	11/30/2010
7842689	Cyclic hydroxylamine as psychoactive compounds A compound of formula (II): in which— R3 and R4 each independently represent hydrogen or C1-6 alkyl; p represent 0 or 1; and R re...	11/30/2010
7842283	Generation of therapeutic microfoam A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersib...	11/30/2010
7842282	Generation of therapeutic microfoam A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersib...	11/30/2010
7814943	Apparatus and method for dispensing foam Apparatus for dispensing foam for the treatment of, inter alia, varicose veins. The apparatus includes a source of foam and a dispensing device which has an inlet in communication with the source of foam, a usable foam outlet, and a waste bleed outlet. The waste ble...	10/19/2010
7811781	Core 2 β(1,6)-acetylglycosaminyltransferase as diagnostic marker for atherosclerosis A method of indicating the presence of the atherosclerosis (particularly coronary artery atherosclerosis) in a subject is provided, comprising comparing the level of Core 2 GlcNAc-T in a tissue sample from a subject with a reference level determined for the same tis...	10/12/2010
7705006	Anti-cancer cyclopenta[g]quinazoline compounds Cyclopenta[g]quinazolines of the formula (I): wherein: A is a group OR or NR0R1 wherein R0 and R1 are each independently hydrogen C1-4 alkyl, C1-4 alkenyl, C1-4 alkynyl, C1-4 hyd...	04/27/2010
7700766	Methanesulfonate salts of abiraterone-3-esters and recovery of salts of abirater one-3-esters from solution in methyl tert-butyl ether A salt of a compound of formula (I) may be made with methanesulfonic acid. The salt and salts with other acids may be prepared by recovering from methyl tert-butyl ether (MTBE). ...	04/20/2010
7589105	Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound Pharmaceutical compositions and methods of treatment are provided for treating amyloidosis, containing, as an active ingredient, at least one nitrogen-containing heteroaryl compound represented by the following general formula or a pharmacologically permitted salt t...	09/15/2009
7528141	Use of cyclopenta[]quinazoline derivatives for treating cancer Method for aiding regression and palliation of a solid tumor in a patient in need of such treatment, comprising administering to the patient an effective amount of a cyclopenta[g]quinazoline of the formula (I) as set forth in the specification, wherein A is hydrogen...	05/05/2009
7514475	Benzylamine analogues A compound of the formula (I): wherein R1 is a C1-C6 alkyl, an amino, a (C1-C6 alkyl)amino, a di(C1-C6 alkyl)amino or a nitrogen-containing satura...	04/07/2009
7504437	Benzylamine analogues A compound of the formula (I): wherein R1 represents C1–C6 alkyl, amino(C1–C6 alkyl)amino, di(C1–C6 alkyl)amino or a nitrogen-containing sat...	03/17/2009
7504393	Benzylamine analogues A compound of the formula (I): wherein R1 is a C1-C6 alkyl group, an amino group, a (C1-C6 alkyl)amino group, a di(C1-C6 alkyl)amino group or a ni...	03/17/2009
7485743	Oligomeric ketone compounds A novel keto8enic compound is provided having general: Formula R(OCH(CH3)CH2C(O))n—O-A wherein n is an integer of 3 to 10, A is the residue of a 3-keto alkan-1-ol and R is selected from the group consisting of H, C1-C6 alkyl and ac...	02/03/2009
7425559	Medicine containing pyrimidine derivative A medicine for central diseases which contains as the active ingredient either a compound represented by the general formula (I): (I) (wherein R1 represents hydrogen or C1-6 alkyl; R2 represents C1-6 alkyl, etc.; A represe...	09/16/2008
7357336	Generation of therapeutic microfoam Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, th...	04/15/2008
7352970	Dispersion management system for soliton optical transmission system A dispersion management system for soliton or soliton-like transmission systems comprises a length of optical fiber (L) in which a plurality of sections (I) made up of components (N,A) of opposite sign dispersions are concatenated together. The duration of the dispe...	04/01/2008
7351736	Therapeutic compositions (II) Method of producing a physiologically acceptable ketosis such as to treat a patient in need of therapy for one or more of Amylotrophic lateral sclerosis, Free Radical disease, Heart failure and Duchenne's muscular dystrophy by oral administration to the patient of a...	04/01/2008
7297701	Anti-cancer cyclopenta [G]quinazoline compounds Cyclopenta[g]quinazolines of the formula (I):—wherein: A is a group OR or NR0R1 wherein R0 and R1 are each independently hydrogen C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl, C2-4 h...	11/20/2007
7279441	Compacted olefin fibers A polyolefin plaque is made by hot compaction of an assembly of fibres of the oriented polymer. It has been found to be beneficial to subject the fibres to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with exce...	10/09/2007
7276537	Formulations of anthraquinone derivatives A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R′R″ of at least 2 carbon atoms and R′ and R″ are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4	10/02/2007
7250511	Process for the preparation of cyclopenta[g]quinazoline derivatives Cyclopenta[g]quinazolines of formula (I), and esters and amides thereof may be made by reacting an ester or amide of formula (II); or a protected derivative thereof with a complex containing the (propargyl)Co2(CO)6+ion	07/31/2007
7235052	Ultrasound detectable instrument with bubble generator Ultrasound detectable instrument including a bubble generator having two elements which, upon contact with each other in the presence of a fluid, react with each other to produce gas bubbles which may be detected by sonic imaging equipment. The two elements comprise...	06/26/2007
7202328	Amorphous polymer article Method of producing an article comprising providing a raw material in the form of a plurality of polymer elements, the polymer elements comprising an amorphous polymer; heating the materials to a temperature above a first predetermined temperature; and compacting th...	04/10/2007

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Assignee: BTG International Limited