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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 7241449 | Transferrin receptor genes of Purified and isolated nucleic acid molecules are provided which encode Tbp2 proteins of M. catarrhalis strains M35, 3 and LES1. The nucleic acid sequence may be used to produce recombinant Tbp2 proteins of the strain of Moraxella free of other proteins... | 07/10/2007 |
| 7015033 | Co-expression of recombination proteins Expression vectors are described which permit the recombinant expression of proteins which essentially contain, in addition to nucleic acid encoding the recombinant protein, nucleic acid encoding a non-proteolytic analog of Haemophilus Hin47 protein, with or ... | 03/21/2006 |
| 7008784 | Non-infectious, non-replicating, immunogenic human immunodeficiency virus-like particles The present invention is directed toward methods for the production of non-infectious, replication-deficient, immunogenic human immunodeficiency virus (HIV)-like particles. These particles are prepared from a recombinant expression vector comprising a heterologous p... | 03/07/2006 |
| 6974581 | Multi-component vaccine comprising at least two antigens from to protect against disease A multi-component immunogenic composition confers protection on an immunized host against infection caused by Haemophilus influenzae. Such composition comprises at least two different antigens of Haemophilus influenzae, one of which is an adhesin. High... | 12/13/2005 |
| 6872814 | Chlamydia antigens and corresponding DNA fragments and uses thereof In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, cont... | 03/29/2005 |
| 6855537 | Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulated factor Strains of Leishmania and other macrophage-infecting parasites are provided which express the GM-CSF gene which are useful in treating hosts infected by the parasite and in protecting hosts against disease caused by infection of hosts by parasites. The parasites are... | 02/15/2005 |
| 6849447 | Protective recombinant Haemophilus influenzae high molecular weight proteins Protective high molecular weight (HMW) proteins are produced recombinantly by expression from E. coli by using a promoter effective in E. coli and a nucleic acid molecule which contains a modified operon of a non-typeable strain of Haemophilus. The mod... | 02/01/2005 |
| 6811783 | Immunogenic compositions for protection against chlamydial infection A protective immune response against Chlamydial infection is achieved by in vivo administration of an immunogenic composition comprising two vectors and a pharmaceutically-acceptable carrier therefor. One of the vectors comprises a first nucleotide sequence encoding... | 11/02/2004 |
| 6808713 | Chlamydia antigens and corresponding DNA fragments and uses thereof The present invention provides a method of immunizing a host against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae. The method involves nucleic acid immunization, including DNA immunization, and employs a vector conta... | 10/26/2004 |
| 6764682 | Adjuvant compositions containing more than one adjuvant Adjuvant compositions for modulating an immune response to an antigen administered to a host comprise a mineral salt adjuvant and at least one other adjuvant. The compositions provide an adjuvanting effect on an antigen which is greater than the adjuvanting effect a... | 07/20/2004 |
| 6696065 | Acellular pertussis vaccines and methods of preparation thereof A multi-component vaccine composition is described comprising acellular pertussis vaccine components, diphtheria toxoid, tetanus toxoid and inactivated poliovirus. The composition also may contain a conjugate of a capsular polysaccharide on Haemophilus in... | 02/24/2004 |
| 6693087 | Nucleic acid molecules encoding POMP91A protein of Chlamydia An isolated and purified nucleic acid molecule encoding a POMP91A protein of a strain of Chlamydia, is useful for nucleic acid immunization of a host, including a human host, against disease caused by infection by a strain of Chlamydia, particularly C. pn... | 02/17/2004 |
| 6686339 | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, ... | 02/03/2004 |
| 6677127 | Nucleic acid respiratory syncytial virus vaccines Vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence locat... | 01/13/2004 |
| 6660275 | Chlamydia antigens and corresponding DNA fragments and uses thereof The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, containing a nucleotide sequenc... | 12/09/2003 |
| 6656472 | Multi oligosaccharide glycoconjugate bacterial meningitis vaccines Multivalent immunogenic molecules comprise a carrier molecule containing at least one functional T-cell epitope and multiple different carbonhydrate fragments each linked to the carrier molecule and each containing at least one functional B-cell epitope. ... | 12/02/2003 |
| 6649370 | Chlamydia antigens and corresponding DNA fragments and uses thereof In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, ... | 11/18/2003 |
| 6642025 | Chlamydia antigens and corresponding DNA fragments and uses thereof In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, ... | 11/04/2003 |
| 6635746 | Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection The immunogenic compositions may comprise the ... | 10/21/2003 |
| 6632663 | DNA immunization against chlamydia infection Nucleic acid, including DNA, immunization is used to generate a protective immune response in a host, including humans, to a serine-threonine kinase (STK) of a strain of Chlamydia. A non-replicating vector, including a plasmid vector, contains a nucleotid... | 10/14/2003 |
| 6623764 | Biodegradable targetable microparticle delivery system Copolymers designed for use as particulate carriers containing functionalizable amino acid subunits for coupling with targeting ligands are described. The copolymers are polyesters composed of -hydroxy acid subunits such as D,L-lactide and pseudo-&... | 09/23/2003 |
| 6572863 | Constitutive expression of non-infectious HIV-like particles Non-infectious, non-replicating immunogenic HIV-like particles are produced by stable long-term constitutive expression in mammalian cells by eliminating elements toxic to the mammalian cells. An expression vector contains a nucleic acid molecule comprisi... | 06/03/2003 |
| 6548070 | Attenuated strains of mycobacteria Attenuated strains of Mycobacterium, particularly species of the tuberculosis complex, have the mycobacterial cell entry (mce) gene functionally disabled. The gene may be disabled by an insertion into the gene which disrupts the mycobacterial cell entry f... | 04/15/2003 |
| 6544527 | Non-infectious, immunogenic, human immunodeficiency virus-like particles devoid of long terminal repeats and a functional pol coding region Non-infectious, retrovirus-like particles contain mutations to reduce gag-dependent RNA-packaging of the gag gene product, eliminate reverse transcriptase activity of the pol gene product, eliminate integrase activity of the pol gene product and eliminate... | 04/08/2003 |
| 6544752 | Anigenically-marked non-infectious retrovirus-like particles Non-infectious, retrovirus-like particles comprise an assembly of an env gene product, a pol gene product and a gag gene product contain an antigenic marker which is non-retroviral or non-HIV retroviral. In one embodiment, the marker comprises an amino ac... | 04/08/2003 |
| 6521745 | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia An isolated and purified nucleic acid molecule encoding an inclusion membrane protein C of a strain of Chlamydia, is useful for nucleic acid immunization of a host, including a human host, against disease caused by infection by a strain of Chlamydia, part... | 02/18/2003 |
| 6518030 | Antigentically-marked non-infectious retrovirus-like particles Non-infectious, retrovirus-like particles comprise an assembly of an env gene product, a pol gene product and a gag gene product contain an antigenic marker which is non-retroviral or non-HIV retroviral. In one embodiment, the marker comprises an amino ac... | 02/11/2003 |
| 6503514 | Attenuated strains of mycobacteria Attenuated strains of Mycobacterium, particularly species of the tuberculosis complex, have the mycobacterial cell entry (mce) gene functionally disabled. The gene may be disabled by an insertion into the gene which disrupts the mycobacterial cell entry f... | 01/07/2003 |
| 6486135 | Nucleic acid respiratory syncytial virus vaccines Non-replicating vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described for in vivo immunization. The nucleotide sequence ... | 11/26/2002 |
| 6475780 | Alphavirus vectors for paramyxovirus vaccines A DNA vector comprises a first DNA sequence which is complementary to at least part of an alphavirus RNA genome and having the complement of complete alphavirus DNA genome replication regions, and a second DNA sequence encoding a paramyxovirus protein, pa... | 11/05/2002 |
| 6471996 | Biodegradable targetable microparticle delivery system Copolymers designed for use as particulate carriers containing functionalizable amino acid subunits for coupling with targeting ligand are described. The copolymers are polyesters composed of -hydroxy acid subunits such as D,L-lactide and -a... | 10/29/2002 |
| 6464979 | Chlamydial vaccines and methods of preparation thereof Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection. The immunogenic compositions may comprise the... | 10/15/2002 |
| 6455050 | Production of virus and purfication of viral envelope proteins for vaccine use Immunogenic envelope glycoproteins are produced from enveloped virus, such as of the paramyxoviridae family, particularly PIV-3 and RSV, by culturing the virus in the substantial absence of exogenous serum proteins, isolating the virus from the tissue cul... | 09/24/2002 |
| 6451322 | Retrovirus like particles made non infectious by a plurality of mutations Non-infectious, retrovirus-like particles contain mutations to reduce gag-dependent RNA-packaging of the gag gene product, eliminate reverse transcriptase activity of the pol gene product, eliminate integrase activity of the pol gene, product and eliminat... | 09/17/2002 |
| 6448386 | High molecular weight major outer membrane protein of moraxella An isolated and purified outer membrane protein of a Moraxella strain, particularly M. catarrhalis, having a molecular mass of about 200 kDa, is provided. The about 200 kDa outer membrane protein as well as nucleic acid molecules encoding the same are use... | 09/10/2002 |
| 6444444 | Genes encoding mycobacterial proteins associated with cell binding and cell entry and uses thereof A gene from a strain of Mycobacterium encoding a protein of molecular weight between about 45 to about 60 kDa and associated with cell binding and cell entry was cloned. The genes and encoded protein have utility in immunogenic preparations or diagnostic ... | 09/03/2002 |
| 6440425 | High molecular weight major outer membrane protein of moraxella An isolated and purified outer membrane protein of a Moraxella strain, particularly M. catarrhalis, having a molecular mass of about 200 kDa, is provided. The about 200 kDa outer membrane protein as well as nucleic acid molecules encoding the same are use... | 08/27/2002 |
| 6440701 | Transferrin receptor genes of Moraxella Purified and isolated nucleic acid molecules are provided which encode transferrin receptor proteins of Moraxella, such as M. catarrhalis or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce reco... | 08/27/2002 |
| 6440424 | High molecular weight major outer membrane protein of moraxella An isolated and purified outer membrane protein of a Moraxella strain, particularly M. catarrhalis, has a molecular mass of about 200 kDa. The about 200 kDa outer membrane protein as well as nucleic acid molecules encoding the same are useful in diagnosti... | 08/27/2002 |
| 6437096 | Transferrin receptor of moraxella Purified and isolated nucleic acid molecules are provided which encode transferrin receptor proteins of Moraxella, such as M. catarrhalis or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce reco... | 08/20/2002 |
