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Assignee: Asubio Pharma Co., Ltd.


Location: Tokyo, JP
No. of patents: 11

NumberTitleIssue Date
7816511Remedies for heart failure
The present invention provides methods for screening drugs inhibiting the expression of OSF-2 gene or the production or function of the protein encoded thereby and therapeutic agents for heart failure having such effects. Useful methods for diagnosing heart failure ...
10/19/2010
7807421Process for production of biopterin compound
The present invention provides a transformed cell which is transformed by at least one gene of enzymes participating in biosynthesis of tetrahydrobiopterin and a process for the production of a biopterin compound using the same. In accordance with the present invent...
10/05/2010
7713972Imidazotriazinone derivatives as PDE 7 (phosphodiesterase 7) inhibitors
The present invention provides the compounds inhibiting PDE 7 selectively, and therefore, enhances cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic disease, inflammatory disease or immunologic disease. ...
05/11/2010
7598228Therapeutic methods and agents for diseases associated with decreased expression of AOP-1 gene or AOP-1
A prophylactic or therapeutic method for a disease associated with decreased expression of AOP-1 gene or AOP-1, comprising (1) transfecting a nucleic acid encoding AOP-1 or a nucleic acid encoding a polypeptide having an addition, deletion or substitution of one or ...
10/06/2009
7582799Method for producing hydrazone derivatives
The present invention provides an industrially advantageous process for producing hydrazone derivative represented by the formula (5), which is shown by the following reaction formula. ...
09/01/2009
7547529Methods for reducing the formation of by-products in the production of recombinant polypeptides
A method for reducing the formation of a byproduct polypeptide containing an O-acetylserine residue in place of a serine residue by adding at least one of histidine, methionine or glycine to the medium in a method for producing a polypeptide containing a serine resi...
06/16/2009
7498344Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same
A pharmaceutical composition, especially a pharmaceutical composition for the alleviation or treatment of symptoms due to ischemic diseases and symptoms derived from seizures, epilepsy, and migraine, and a Ca2+ overload suppressant, containing an arylpipe...
03/03/2009
7459551Method for preparing cyclic compounds
The present invention provides a method for preparing a β-lactam compound of the following Formula (3), which comprises the step of reacting a compound of the following Formula (1) with a trialkyl phosphite represented by the formula (R5O)3P (...
12/02/2008
7449177Remedy for pemphigoid
An agent for treatment of pemphigoid is provided. For use as an agent for treatment of pemphigoid, IFN-γ is administered in a dose of 2,000,000 JRU once daily for 7 days by intravenous drip infusion. Depending on symptoms, side effects and age of a patient, ...
11/11/2008
7361759Method for producing L-biopterin
To provide a method for producing L-biopterin on a large industrial scale by using a reagent which is inexpensive and easy to handle, without requiring a use of any particular equipment or plants. A method for porducing a biopterin derivative represented by t...
04/22/2008
7358356Processes for preparation of organic compounds
The present invention provides a method for preparing an organic compound, which comprises a dehydration step of distilling off water from a polar organic solvent solution containing the organic compound and water to bring the concentration of water below a given le...
04/15/2008
 
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