Assignee: Arch Development Corporation

Location: Chicago, IL
No. of patents: 277

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Number	Title	Issue Date
7838512	DNA damaging agents in combination with tyrosine kinase inhibitors Methods and compositions for enhancing cancer cell death using therapeutically effective amounts of DNA damaging agent(s) that act in combination to enhance cancer cell death, e.g., nucleic acid precursors, and protein tyrosine kinase inhibitors, e.g., that inhibit ...	11/23/2010
7799535	Methods for identifying factors that control the folding of amyloid proteins of diverse origin The present invention provides a yeast cell based system for determining factors that control the folding of amyloid proteins of diverse origins. Further the present invention provides methods of using such a system to screen for reagents that affect amyloid formati...	09/21/2010
7227177	Doped semiconductor nanocrystals A particle, includes a semiconductor nanocrystal. The nanocrystal is doped. ...	06/05/2007
7192711	Compositions and methods involving methyladenosine phosphorylase in the diagnosis and treatment of proliferative disorders Disclosed are novel nucleic acid and peptide compositions comprising methylthioadenosine phosphorylase (MTAP) and methods of use for MTAP amino acid sequences and DNA segments comprising MTAP in the diagnosis of human cancers and development of MTAP-specific antibod...	03/20/2007
7184582	Method, system and computer readable medium for an intelligent search workstation for computer assisted interpretation of medical images A method, system and computer readable medium for an intelligent search display into which an automated computerized image analysis has been incorporated. Upon viewing an unknown mammographic case, the display shows both the computer classification output as well as...	02/27/2007
7169764	Promoter for smooth muscle cell expression Disclosed is a smooth muscle cell specific promoter, the SM22α gene promoter as well as the murine cDNA and genomic SM22α nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based...	01/30/2007
7133203	Apparatus for applying optical gradient forces A method and apparatus for control of optical trap arrays and formation of particle arrays. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control of optical trap arrays and consequent control of particle a...	11/07/2006
7115258	Vesicular monoamine transporter gene therapy in parkinson's disease The present invention provides methods and compositions for the therapeutic intervention of Parkinson's disease. More particularly, methods of making and sequestering dopamine are disclosed. Additionally, methods of genetically modifying donor cells by gene transfer...	10/03/2006
7078387	Efficient and stable gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors This invention relates to the use of recombinant adeno-associated virus (rAAV) vectors to transduce cardiomyocytes in vivo by infusing the rAAV into a coronary artery or coronary sinus. rAAV infection is not associated with detectable myocardial inflammation or myoc...	07/18/2006
7043066	System for computerized processing of chest radiographic images A method, system and computer readable medium for computerized processing of chest images including obtaining a digital first image of a chest (S100); producing a second image which is a mirror image (S300) of the first image; performing image warping ...	05/09/2006
6984619	Method for protection against tumor metastasis formation Methods and pharmaceuticals for inhibiting or preventing metastasis formation in animals, including humans, having primary tumors, through the administration of phosphorothioates including their thiol and disulfide metabolites are disclosed. These compounds stimulat...	01/10/2006
6972196	Making surfaces inert by modifying with alkanethiolates Alkanethiols of formula (1) and the enantiomers of the alkanethiol of formula (1): HS-L-Q-T (1), and disulfides of formula (3) and the enantiomers of the disulfide of formula (3): T-Q-L S-S-J (3), where -T is a moiet...	12/06/2005
6939604	Doped semiconductor nanocrystals A particle, includes a semiconductor nanocrystal. The nanocrystal is doped. ...	09/06/2005
6916610	Method for generation of longer cDNA fragments from sage tags for gene identification Generation of longer cDNA fragments from SAGE tags for gene identification (GLGI) is disclosed. This method converts SAGE tags, which are about 10 base pairs in length, into their corresponding 3′ cDNA fragments covering hundred bases. This added information provi...	07/12/2005
6901156	Method, system and computer readable medium for an intelligent search workstation for computer assisted interpretation of medical images A method, system and computer readable medium for an intelligent search display into which an automated computerized image analysis has been incorporated. Upon viewing an unknown mammographic case, the display shows both the computer classification output as well as...	05/31/2005
6898303	Method, system and computer readable medium for the two-dimensional and three-dimensional detection of lesions in computed tomography scans A method, system and computer readable medium for automated detection of lung nodules in computed tomography (CT) image scans, including generating two-dimensional segmented lung images by segmenting a plurality of two-dimensional CT image sections derived from the ...	05/24/2005
6870037	Methylthioadenosine phosphorylase compositions and methods of use in the diagnosis and treatment of proliferative disorders Disclosed are novel nucleic acid and peptide compositions comprising methythlioadenosine phosphorylase (MTAP) and methods of use for MTAP amino acid sequences and DNA segments comprising MTAP in the diagnosis of human cancers and development of MTAP-specific antibod...	03/22/2005
6836558	Method, system and computer readable medium for identifying chest radiographs using image mapping and template matching techniques A method, system and computer readable medium for a computer-automated method for identifying given image data, including obtaining template image data corresponding to said given image data; calculating correlation values between the given image data and said templ...	12/28/2004
6764768	Controlled release composition An alkanethiol of formula (1): HS—L—Q1—T—Q2—M—G—Z (1), may for a SAM. Under application of a potential to the surface, the leaving group —Z is released. ...	07/20/2004
6738499	System for detection of malignancy in pulmonary nodules A method, computer program product, and system (100) for computerized analysis of the likelihood of malignancy in a pulmonary nodule using artificial neural networks (ANNs) (S4). The method, on which the computer program product and the system is based...	05/18/2004
6724925	Method and system for the automated delineation of lung regions and costophrenic angles in chest radiographs A method, system, and computer product for the automated segmentation of the lung fields and costophrenic angle (CP) regions in posteroanterior (PA) chest radiographs, wherein image segmentation based on gray-level threshold analysis is performed by applying an iter...	04/20/2004
6723511	Herpes simplex virus ICP4 is an inhibitor of apoptosis The ICP4 protein of herpes simplex virus plays an important role in the transactivation of viral genes. The present invention discloses that ICP4 also has the ability to inhibit apoptosis. This function appears to reside in functional domain distinct from the transa...	04/20/2004
6694046	Automated computerized scheme for distinction between benign and malignant solitary pulmonary nodules on chest images An automated method for analyzing a nodule and a computer storage medium storing computer instructions by which the method can be implemented when the instructions are loaded into a computer to program the computer. The method includes obtaining a digital...	02/17/2004
6683973	Process, system and computer readable medium for pulmonary nodule detection using multiple-templates matching A method to determine whether a candidate abnormality in a medical digital image is an actual abnormality, a system which implements the method, and a computer readable medium which stores program steps to implement the method, wherein the method includes...	01/27/2004
6682918	Bacterial sucrose synthase compositions and methods of use The present invention provides isolated and purified polynucleotides that encode bacterial polypeptides that participate in the utilization of sucrose. Isolated bacterial sucrose synthase compositions and methods of use are provided. Processes for alterin...	01/27/2004
6645955	3,6-dihydroxy-24-amidyl steroid derivatives Steroid derivatives of this invention interact with nuclear liver X receptor (LXR) and ubiquitous receptor (UR) and can be used to treat a variety of LXR- or UR-mediated disorders....	11/11/2003
6624940	Method for applying optical gradient forces and moving material An apparatus and method for manipulating small dielectric particles. The apparatus and method involves use of a diffractive optical element which receives a laser beam and forms a plurality of light beams. These light beams are operated on by a telescope ...	09/23/2003
6613319	Long-term expression of erythropoietin and growth hormone by transforming muscle cells A process for increasing the circulating levels of gene products in a primate for extended period of time is provided. In accordance with that process, muscle cells of the mammal are transformed with an expression vector that contains a polynucleotide tha...	09/02/2003
6605712	Gene transcription and ionizing radiation: methods and compositions The present invention provides a DNA molecule comprising a radiation responsive enhancer-promoter operatively linked to an encoding region that encodes at least one polypeptide. An encoding region can comprise a single encoding sequence for a polypeptide ...	08/12/2003
6594378	Method, system and computer readable medium for computerized processing of contralateral and temporal subtraction images using elastic matching A method, system and computer readable medium of computerized processing of chest images including obtaining digital first and second images of a chest and detecting rib edges in at least one of the first and second images. The rib edges are detected by c...	07/15/2003
6577752	Automated method and system for the delineation of the chest wall in computed tomography scans for the assessment of pleural disease A method, system, and computer program product for automated measurements of pleural space and/or pleural thickening in thoracic CT images to identify the presence and quantify the extent of pleura-based disease, including obtaining a CT image including t...	06/10/2003
6576660	Methods and compositions for regulation of 5-଱-reductase activity Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness....	06/10/2003
6567567	Sampling and reconstruction of RF signals A method and apparatus are provided for transceiving a signal. The method includes the steps of transmitting a superposed frequency component of the signal within each of a plurality of non-adjacent frequency bands, using analogue or digital filters withi...	05/20/2003
6558665	Encapsulating particles with coatings that conform to size and shape of the particles Particles such as islet cells are encapsulated by a method that forms a coating of uniform thickness that conforms to the size and shape of the particles. Two substantially immiscible liquids of different densities are provided in a container as upper and...	05/06/2003
6553334	System for surveillance of spectral signals A method and system for monitoring at least one of a system, a process and a data source. A method and system have been developed for carrying out surveillance, testing and modification of an ongoing process or other source of data, such as a spectroscopi...	04/22/2003
6547811	Method for inducing hypothermia Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling ar...	04/15/2003
6534290	Methods for production of growth-promoting proteins and peptides for kidney epithelial cells Novel growth peptides derived from protein factors having molecular weights of about 22 and 45 kDa stimulate mitogenic activity of epithelial, but not fibroblastic cells, in particular, kidney epithelial cells. A source of the factors is scrape-wounded ki...	03/18/2003
6528793	Accurate image reconstruction for DOI-PET system A method and apparatus are provided for reconstructing images from data obtained from scintillation events occurring within a projection space of a depth-of-interaction positron emission tomography system. The method includes the steps of identifying a se...	03/04/2003
6524832	DNA damaging agents in combination with tyrosine kinase inhibitors The present invention relates to the signalling pathways connecting DNA damage, such as that induced by ionizing radiation or alkylating agents, and phosphorylation by tyrosine kinases....	02/25/2003
6511603	Alkaline earth cation extraction from acid solution An extractant medium for extracting alkaline earth cations from an aqueous acidic sample solution is described as are a method and apparatus for using the same. The separation medium is free of diluent, free-flowing and particulate, and comprises a Crown ...	01/28/2003

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Assignee: Arch Development Corporation