Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 8067399 | Method and apparatus for transdermal or transmucosal application of testosterone Methods, formulations, and devices for providing transdermal or transmucosal delivery of active agents to subjects in need thereof. The formulations and methods treat symptoms of hormonal disorders including hypogonadism, female sexual desire disorder, female menopa... | 11/29/2011 |
| 7470433 | Formulations for transdermal or transmucosal application The present invention relates generally to formulations for transdermal or transmucosal administration of an active agent such as estradiol. The invention is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of l... | 12/30/2008 |
| 7425340 | Permeation enhancing compositions for anticholinergic agents A transdermal or topical composition including anticholinergic agents, such as oxybutynin, a urea-containing compound and a carrier system. A method is disclosed for treating a subject for urinary incontinence while reducing the incidences of peak concentrations of ... | 09/16/2008 |
| 7404965 | Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels A pharmaceutical composition in the form of a solution, cream, lotion, spray, ointment, gel, aerosol, tablet, suppository or patch device for transdermal or transmucosal administration of alprazolam to a subject, which includes as a permeation enhancing mixture a fa... | 07/29/2008 |
| 7387788 | Pharmaceutical compositions of nicotine and methods of use thereof The present invention comprises non occlusive compositions for transdermal delivery of nicotine, and more particularly pharmaceutically acceptable salts thereof, and methods of making same. The composition may, for example, be a gel suitable for transdermal or trans... | 06/17/2008 |
| 7335379 | Transdermal pharmaceutical formulation for minimizing skin residues This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The novel formulation includes at least one pharmacologically act... | 02/26/2008 |
| 7214381 | Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels The present invention refers to a pharmaceutical composition suitable for the transdermal or transmucosal administration of one or more active agents, in form of a gel or a solution, comprising as a permeation enhancers a combination of: a) saturated fatty alcohol o... | 05/08/2007 |
| 7198801 | Formulations for transdermal or transmucosal application The present invention relates generally to formulations for transdermal or transmucosal administration of an active agent. The invention is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty al... | 04/03/2007 |
| 6696085 | Use of an acrylic type polymer as disintegrating agent The present invention provides for the use of a polymer of the acrylic type as a disintegration agent.... | 02/24/2004 |