"The idea that cavalry will be replaced by these iron coaches is absurd. It is little short of treasonous."
Aide-de-camp to Field Marshal Haig ; At a tank demonstration, 1916
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| Number | Title | Issue Date |
| 6756564 | System and method for removing particulate created from a drilled or cut surface A method for receiving and collecting particulate matter from drilled or cut holes in a tablet on a turntable and transporting said particulate to a remote location is described. ... | 06/29/2004 |
| 6210716 | Controlled release bupropion formulation A controlled release dosage form of bupropion hydrochloride which comprises: (a) a first pellet having a core of bupropion hydrochloride and hydroxypropyl methylcellulose at a weight ratio of 10:1 to 30:1 and a coating of a mixture of an acrylic resin whi... | 04/03/2001 |
| 6197347 | Oral dosage for the controlled release of analgesic An oral dosage form that provides for the controlled release of an analgesic wherein the dosage form comprises a core containing an analgesic that is coated with a mixture of an enteric polymer, a water insoluble polymer and a lubricant.... | 03/06/2001 |
| 6177102 | Once daily analgesic tablet An analgesic controlled release dosage form containing: (a) 40-80 weight percent of an analgesic; (b) 10-30 weight percent of a pharmaceutically acceptable filler; and (c) 10-30 weight percent of a carrier base wherein the carrier base is formed from a hi... | 01/23/2001 |
| 6174548 | Omeprazole formulation A pharmaceutical composition of omeprazole for oral administration is described which consists essentially of: (a) a tabletted core component containing a therapeutically effective amount of omeprazole, a surface active agent, a filler, a pharmaceutically ... | 01/16/2001 |
| 6103263 | Delayed pulse release hydrogel matrix tablet The invention provides a delayed-pulse controlled release pharmaceutical tablet having: (a) from 20 to 60 wt. % of a low molecular weight hydroxypropyl cellulose having a number average molecular weight of 70,000 to 90,000; (b) from 4 to 10 wt. % of a high mol... | 08/15/2000 |
| 6099859 | Controlled release oral tablet having a unitary core A controlled release antihyperglycemic tablet that does not contain an expanding polymer and comprising a core containing the antihyperglycemic drug, a semipermeable membrane coating the core and at least one passageway in the membrane.... | 08/08/2000 |
| 6096340 | Omeprazole formulation A pharmaceutical composition of omeprazole for oral administration is described which consists essentially of: (a) a pellet comprising an inert core component, a therapeutically effective amount of omeprazole, a surface active agent, a filler, a pharmaceu... | 08/01/2000 |
| 6077541 | Omeprazole formulation A pharmaceutical composition of omeprazole for oral administration is described which consists essentially of: (a) a pellet comprising an inert core component, a therapeutically effective amount of omeprazole, a surface active agent, a filler, a pharmaceu... | 06/20/2000 |
| 5916595 | HMG co-reductase inhibitor A controlled release dosage formulation is described which is based on a combination of: (a) a compressed tablet core which contains an alkyl ester of a hydroxy substituted naphthalene derivative a pharmaceutically acceptable, water swellable polymer and ... | 06/29/1999 |
| 5837379 | Once daily pharmaceutical tablet having a unitary core A controlled release nifedipine tablet which comprises: (a) a homogeneous compressed core which comprises: (i) a medicament; (ii) a water soluble osmotic compound (iii) one or more osmotic polymers; and (b) a membrane coating which completely covers said core tablet whi... | 11/17/1998 |
| 5834023 | Diltiazem controlled release formulation A once-a-day controlled release diltiazem formulation is described which includes: (a) from 20 to 50% by weight of enteric polymeric membrane coated pellets comprising a polymer membrane coated core which comprises a biologically inert core which is coate... | 11/10/1998 |
| 5830503 | Enteric coated diltiazem once-a-day formulation A once-a-day diltiazem dosage form which comprises: (a) a core element which is a compressed tablet which contains a therapeutic dose of diltiazem and an amount of a solubility modulating substance that controls the release of said diltiazem in order to p... | 11/03/1998 |
| 5736159 | Controlled release formulation for water insoluble drugs in which a passageway is formed in situ A controlled release pharmaceutical tablet is disclosed which is based on: (a) a compressed core which contains: (i) a medicament; (ii) at least 23% to 55% by weight, based on the total weight of the core, of a water soluble osmotic agent; (iii) a water soluble pha... | 04/07/1998 |
| 5728402 | Controlled release formulation of captopril or a prodrug of captopril The invention provides a controlled release pharmaceutical unit dose composition for oral administration which comprises: (a) an internal phase which comprises captopril or a prodrug of captopril in admixture with a hydrogel forming agent; and (b) an exte... | 03/17/1998 |
| 5654005 | Controlled release formulation having a preformed passageway A controlled release pharmaceutical tablet having at least one passageway, said tablet having: (a) a compressed core which comprises: (i) a medicament; (ii) an amount of a water soluble osmotic agent which is effective to cause the medicament to be delivered f... | 08/05/1997 |
| 5567441 | Diltiazem controlled release formulation A once-a-day controlled release diltiazem formulation is described which includes: (a) from 20 to 50% by weight of enteric polymeric membrane coated pellets comprising a polymer membrane coated core which comprises a biologically inert core which is coate... | 10/22/1996 |
| 5558879 | Controlled release formulation for water soluble drugs in which a passageway is formed in situ A controlled release pharmaceutical tablet is disclosed which is based on: (a) a compressed core which contains: (i) a medicament; (ii) from 5 to 20% by weight of a water soluble osmotic agent based on the total weight of the compressed core; (iii) a water soluble ... | 09/24/1996 |
| 5532275 | Method of promoting wound healing and scar regression A novel method of treating wounds has been discovered that is based on the system and/or topically administration of an effective amount, of para-amino benzoic acid or its derivatives, to a patient who has a wound, the healing of the wound will be promote... | 07/02/1996 |
| 5508040 | Multiparticulate pulsatile drug delivery system A unit dosage form of capsule, tablet or the like is composed of a large number of pellets made up of two or more populations of pellets or particles. Each pellet contains a core containing the therapeutic drug and a water soluble osmotic agent. A water-p... | 04/16/1996 |
| 5472708 | Pulsatile particles drug delivery system Unit dosage form for delivering drugs into the body in a series of sequential, pulsatile releasing events employs conventional pharmaceutical equipment and processes for optimum economy, reliability, and bioavailability. The system can be used with drugs ... | 12/05/1995 |
| 5458887 | Controlled release tablet formulation The present invention is directed to a controlled release dosage form which may be made using an osmotic core which contains a drug containing phase which includes a water swellable component and a continuous coating which comprises a major amount of a wa... | 10/17/1995 |
| 5458888 | Controlled release tablet formulation The present invention provides a controlled release dosage form which may be made using a blend having an internal drug containing phase and an external phase which comprises a polyethylene glycol polymer which has a weight average molecular weight of fro... | 10/17/1995 |
| 5419917 | Controlled release hydrogel formulation The invention is directed to a method for the modification of the rate of release of a drug from a hydrogel which is based on the use of an effective amount of a pharmaceutically acceptable ionizable compound that is capable of providing a substantially z... | 05/30/1995 |
| 5397574 | Controlled release potassium dosage form A pharmaceutical composition for oral administration of potassium salt in a form not irritating to the gastrointestinal mucosa comprises tablets or capsules of micropellets of a potassium salt, such as potassium chloride. The micropellets are coated with ... | 03/14/1995 |