Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6074829 | Relating to assay systems A method for detecting an interaction between two proteins while eliminating false positive interactions, the method being particularly useful for application in the two-hybrid system and for the screening of libraries of unknown proteins. In a two-hybrid... | 06/13/2000 |
| 5997843 | Radiometal complexes that localise in hypoxic tissue Methods of imaging and radiotherapy of hypoxic tissues are provided using radiometal complexes not substituted by a hypoxia-localizing moiety.... | 12/07/1999 |
| 5948620 | Reverse two-hybrid system employing post-translation signal modulation The invention relates to modified two-hybrid systems, in particular a reverse two-hybrid system which employs as a reporter a gene encoding a modifying agent such as an enzyme, and a signal agent which is modified by the enzyme usually by being broken dow... | 09/07/1999 |
| 5932441 | Vectors for differential expression DNA constructs and vectors are provided for differential expression of proteins in different expression systems, to enable expression of a protein of interest alone or as part of a fusion protein without the need to transfer the coding sequence for the pr... | 08/03/1999 |
| 5864032 | Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides Phosphoramidite derivatives of formula (V), ##STR1## wherein X is biotin and Y is a protecting group. There may be a linker arm, of variable length, between X and the rest of the molecule. Examples of the protecting group Y include 4,4'-dimethoxytrit... | 01/26/1999 |
| 5823379 | Sealed container for hazardous material A container suitable for use in the transportation of hazardous materials, for example radiolabelled material, has a base cup member (12) which is closed by a threaded lid (13). Within the cup member (12) a liner (17) is provided within an inner cavity (1... | 10/20/1998 |
| 5705143 | Biological targeting agents A conjugate comprises a linear or cyclic synthetic peptide of 3-50 amino acids linked via one of its carboxyl groups and optionally via a linking group, to a polydentate metal chelating group, with the result that endo- or exo-peptidase metabolism of the ... | 01/06/1998 |
| 5705345 | Methods and kits for preparing nucleic acids using cyclodextrin A method of preparing nucleic acids by obtaining an impure nucleic acid preparation, treating said preparation with phenol and adding a cyclodextrin to the treated preparation to neutralize the phenol.... | 01/06/1998 |
| 5702925 | Nucleoside analogue method A method is provided of making a dideoxynucleoside mono-or tri-phosphate, which is optionally 32-P or 33-P or 35-S radiolabelled which involves reacting the corresponding dideoxynucleoside with an optionally radiolabelled nucleotide phosphate or thiophosp... | 12/30/1997 |
| 5690904 | Diagnostic radiopharmaceutical compounds (That) Tetradentate ligands are used to form neutral 99m-technetium complexes which may be useful as radiopharmaceuticals e.g. as brain imaging agents. The ligands have the structure ##STR1## where n is 2 or 3, m is 0-4, R is H or substituted or unsubstitut... | 11/25/1997 |
| 5686058 | Radiolabelled nucleotide formulations stored in an unfrozen state Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilizers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xy... | 11/11/1997 |
| 5681946 | Precipitating polymers A method of recovering a biopolymer from solution involves the use of magnetically attractable beads which do not specifically bind the polymer. The beads are suspended in the solution. Then the polymer is precipitated out of solution and becomes non-spec... | 10/28/1997 |
| 5670346 | Modifying nucleotide analogues Fluorescently labelled dideoxynucleoside triphosphates are widely used as chain-terminators in Sanger dideoxy sequencing operations. But these unincorporated dye-terminators migrate in an electrophoresis gel and obscure the desired sequence ladder. This i... | 09/23/1997 |
| 5667763 | Radiolabelled amino acid formulations stored in an unfrozen state Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilizers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xy... | 09/16/1997 |
| 5665554 | Magnetic bead precipitation method A method of recovering a first material, e.g. plasmid DNA, from a solution containing pre-precipitated second material, e.g. genomic DNA and cellular debris, by precipitating the first material in the presence of magnetically attractable beads which becom... | 09/09/1997 |
| 5665562 | Devices and methods for the measurement of cellular biochemical processes Apparatus and method for studying cellular processes comprise a vessel having a base including a layer comprising a scintillant substance and which is adapted for attachment and/or growth of cells. Cellular processes are examined by scintillation proximit... | 09/09/1997 |
| 5665544 | RNA fingerprinting to determine RNA population differences A method of producing an RNA fingerprint of a poly(A)+ RNA preparation. At least one oligonucleotide primer and a supply of nucleotides of which one is a terminator nucleotide, are added to the poly(A)+ RNA preparation or a single-st... | 09/09/1997 |
| 5658494 | Fluorescent compounds Novel compounds obtainable by reacting together an imido-reagent such as diphenylphosphonimido-triphenylphosphorane), or a phosphine oxide such as p-tolyldiphenylphosphine oxide, with a chelate of a transition or lanthanide or actinide metal, such as tris... | 08/19/1997 |
| 5589576 | Cores for technetium radiopharmaceuticals Novel complexes of technetium (99 Tc or 99m Tc) which contain the moiety Tc.dbd.NR, Tc--N.dbd.NY or Tc(--N.dbd.NY)2, and a ligand which confers biological target-seeking properties on the complex, wherein R represents an a... | 12/31/1996 |
| 5544535 | Pipetting device An automatic device has a pipette (46) which is movable by motors along a guided path (48) between first and second locations at which a supply and storage vial (43) and a rack (45) for carrying one or more receptacle tubes (44) are respectively positione... | 08/13/1996 |
| 5494654 | Radiolabelled compound formulations Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xy... | 02/27/1996 |
| 5480803 | Apparatus for treating analytes An apparatus includes an enclosed chamber in which a motor-driven cylinder is mounted for rotation about a horizontal axis. The lower half of the cylinder is disposed in a trough. A blot can be attached, analyte side outward, to the surface of the cylinde... | 01/02/1996 |
| 5449494 | Sampling device A sampling device includes a cylindrical tube having a smaller diameter portion in which a plunger is mounted for sliding sealing movement. The inner end of the cylinder is sealed from the interior of the tube by a rupturable element, and the plunger has ... | 09/12/1995 |
| 5312904 | Cationic complexes of technetium-99M Tridentate mono-anionic ligands have the structure X-A-Y-Q-Z where each of X and Y is independently P, As or N, Z is phenol, thiophenol or thiol, and A and Q are hydrocarbon linking groups. The ligands from cationic complexes with Technetium-99m, e.g. [TcIII ... | 05/17/1994 |
| 5304465 | Enzyme assay method using surface plasmon resonance spectroscopy Method of performing enzyme assays using the technique of surface plasmon resonance spectrometry (SPRS). An SPRS surface carries an immobilized reagent which is capable of being released by an enzyme. A fluid sample containing the enzyme is brought into c... | 04/19/1994 |
| 5278080 | Method for measuring the free fraction of ligands in biological fluids A one-step assay for the free portion of a ligand in a biological sample involves incubating a mixture of the sample with a labelled antibody for the ligand and a ligand analogue which competes with the ligand for binding to the antibody. The assay is cha... | 01/11/1994 |
| 5064619 | Biological sensors A surface plasmon resonance (SPR) detector includes a laser source for generating radiation which is reflected off a concave reflector to a point or line of incidence on the interface between a glass slide and a metal layer. A single pencil beam from the ... | 11/12/1991 |
| 5055265 | Biological sensors The present invention is drawn to a surface plasmon resonance (SPR) sensor in which the phenomenon of long-range surface plasmon resonance is used to develop a highly sensitive detector for use in biological, biochemical or general chemical testing. The s... | 10/08/1991 |
| 5047633 | Imaging apparatus and method Apparatus for the high resolution imaging of macromolecules and interactions involving macromolecules. The apparatus comprises a surface (10) on which the macromolecule under test is placed and a plurality of fine probes (13). Means (not shown) are provid... | 09/10/1991 |
| 5045302 | Ligands and cationic complexes thereof with technetium-99m This invention concerns novel bidentate ligands L having two phosphorus or arsenic atoms. Cationic complexes of the ligands with Technetium-99m, e.g. having the formula [TcO2 L2 ]+, are useful for body imaging, particularl... | 09/03/1991 |
| 5035863 | Surface plasmon resonance sensors A surface plasmon resonance (SPR) sensor is adapted for biochemical and similar testing on large area samples such as the gel of an electrophoresis apparatus. The gel is sandwiched between a pair of plates. One of the plates is of transparent material and... | 07/30/1991 |
| 5017882 | Proton source In a proton/neutron source incorporating a cyclotron, in particular a superconducting cyclotron having a cylindrical superconducting magnet incorporating superconducting magnetic coils associated with pole pieces, a stream of ionized particles, such as H | 05/21/1991 |
| 4997278 | Biological sensors A sensor uses the principle of surface plasmon resonance (SPR) to monitor the progress of the reaction between a sample and a sensitive layer (for example an antibody layer). The layer is applied to the rear surface of a metallic film formed on the surfac... | 03/05/1991 |
| 4889606 | Electrophoresis and transfer for A method and apparatus for use in biological testing. The apparatus comprises electrophoresis apparatus comprising a tank (1) the interior of which is formed with a raised portion (5) which splits the tank into the two compartments (6,7) containing electr... | 12/26/1989 |
| 4886360 | Method and apparatus for particle analysis The apparatus comprises a cell 2 containing the sample 1 under investigation. Electromagnetic waves P1,P2 are applied from opposite directions and interfere with one another in the region of the cell to form a standing wave pattern 6. DUe to electrostrict... | 12/12/1989 |
| 4783305 | Generator for radionuclide A generator of radionuclides comprises a generator column (10) containing the radionuclide and provided with an inlet (12) and an outlet (14) for eluent, first and second reservoirs (16, 18) for eluent, and connecting means for passing a pre-determined co... | 11/08/1988 |
| 4745077 | Method of performing assay for analyte in liquid medium The invention concerns assays, such a immunoassays or two-site immunometric assays, performed using a labelled reagent and another reagent bound to magnetically attractable particles which are suspendable but insoluble in a liquid assay medium. After the ... | 05/17/1988 |
| 4731336 | Immunoassay for complement fragments A method for assaying complement fragment C3 a, C4 a or C5 a or the des-Arg derivative thereof in a biological sample which comprises combining equal volumes of the biological sample and a solution of 0.8 to 1.6% of an acr... | 03/15/1988 |
| 4716106 | Detecting polynucleotide sequences A method of detecting a target polynucleotide sequence in a sample uses a labelled polynucleotide secondary probe, and a polynucleotide primary probe having sequences complementary to both the target and the secondary probe. The sample, immobilized or in ... | 12/29/1987 |
| 4715988 | Standard for analysis A block of polymeric material 12 comprises label layers 14 and interposed non-label layers 16, each label layer containing a different known concentration of a label material. The block can be sliced by a microtome 18 into thin section each of which is us... | 12/29/1987 |
