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| Number | Title | Issue Date |
| 8044065 | Benzothienopyridines for use as inhibitors of Eg5 kinesin Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity. ... | 10/25/2011 |
| 7781453 | Aminopyridine-derivatives The compounds of Formula (I) in which R1, R2, R3 and R4 have the meanings as given in the description are novel effective iNOS inhibitors. ... | 08/24/2010 |
| 7709488 | Imidazopyridine-derivatives as inducible no-synthase inhibitors The compounds of formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors. ... | 05/04/2010 |
| 7468377 | Imidazopyridine-derivatives as inductible no-synthase inhibitors The compounds of Formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors. ... | 12/23/2008 |
| 7393860 | Tetrahydropyridoethers The compound (7R,8R,9R)-2,3-Dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-tetrahydro-imidazo-[1,2-h] [1,7] naphthyridine inhibits the secretion of gastric acid. ... | 07/01/2008 |
| 7390819 | Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors The compounds of formula I in which R1, R2, R3 and A have the meanings as given in the description are novel effective INOS inhibitors. ... | 06/24/2008 |
| 7329677 | Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors The compounds of formula (I) in which R1, R2, R3, R4 and R11 have the meanings as given in the description are novel effective iNOS inhibitors. ... | 02/12/2008 |
| 7326718 | 8-Substituted imidazopyridines The present invention relates to 8-substituted imidazopyridines of a certain formula (1) in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion... | 02/05/2008 |
| 7326784 | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives The invention relates to compounds of the formula 1, in which R1, R2, R3, Arom and PG have the meanings as indicated in the description. These compounds are valuable intermediates for the preparation of pharmaceu... | 02/05/2008 |
| 7317021 | Aminopyridine-derivatives as inductible no-synthase inhibitors The compounds of Formula (I) in which R1, R2, R3 and R4 have the meanings as given in the description are novel effective iNOS inhibitors. ... | 01/08/2008 |
| 7307084 | Cyclic benzimidazoles The invention relates to cyclic benzimidazoles of formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and in... | 12/11/2007 |
| 7256293 | Imidazopyridine intermediates The invention relates to compounds of the formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceu... | 08/14/2007 |
| 7247317 | Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or adult respiratory distress syndrome (ARDS) and infant respiratory distress syndrome (IRDS) Novel compositions for the treatment of IRDS and ARDS are indicated which contain a compound of formula (I), in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound and lung surfactant | 07/24/2007 |
| 7238664 | Composition comprising a pulmonary surfactant and a PDE5 inhibitor for the treatment of lung diseases The invention relates to the combined administration of a pulmonary surfactant and a PDE5 inhibitor for the treatment of a disease in which pulmonary surfactant malfunction and/or phosphodiesterase 5 (PDE5) activity is detrimental. ... | 07/03/2007 |
| 7223771 | Tricyclic imidazopyridines The invention provides compounds of the formula (I), in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid. ... | 05/29/2007 |
| 7202055 | Process for the production of proteins and the production of arrays of proteins Described is a novel process for the production of at least one protein of interest by secretion of the protein of interest from a pro- or eukaryotic host cell in a compartment system, which host cell is stably expressing a secretion system and capable of heterologo... | 04/10/2007 |
| 7189736 | Prodrugs of imidazopyridine derivatives Compounds of formula 1, in which the substituents have the meanings mentioned in the description are suitable for the prevention and treatment of gastrointestinal diseases. ... | 03/13/2007 |
| 7186710 | Phthalazinones The compounds of formula I in which R1, R2, R3, R4 and R5 have the meanings as given in the description are PDE4/7 inhibitors. ... | 03/06/2007 |
| 7179810 | Phthalazinone-piperidino-derivatives as PDE4 inhibitors The compounds of formula I in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors. ... | 02/20/2007 |
| 7175854 | Pharmaceutical preparation comprising an active dispersed on a matrix The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation an ... | 02/13/2007 |
| 7173009 | Surfactant protein C esters Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described. ... | 02/06/2007 |
| 7147869 | Rapidly disintegrating tablet comprising an acid-labile active ingredient A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together... | 12/12/2006 |
| 7141567 | Polysubstituted imidazopyridines as gastric secretion inhibitors The invention relates to imidazopyridines of a certain formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion-inhibiting properties. ... | 11/28/2006 |
| 7138399 | Alkoxypyridine-derivatives The compounds of formula I in which R1 is 1–4C-alkoxy, A is 1–4C-alkylene, B represents 3H-imidazo[4,5-b]pyridin-2-yl, 3H-imidazo[4,5-b]pyridin-2-yl substituted by R2 and/or R3, 9H-purin-8-yl or 9H-purin-8-yl... | 11/21/2006 |
| 7135452 | Recombinant SP-A for the treatment or prevention of pulmonary infection and inflammation Recombinant surfactant protein A and pharmaceutical compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation. ... | 11/14/2006 |
| 7105676 | Tetrahydropyridoethers Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases. ... | 09/12/2006 |
| 7101911 | Tryptase inhibitors Compounds of the formula I, in which M, A1, A2, K1 and K2 have the meanings given in the description are novel effective tryptase inhibitors. ... | 09/05/2006 |
| 7060716 | Tryptase inhibitors Compounds of the formula (I), in which M is a central building block selected from the group below in which A1, A2, K1 and K2 are as defined in the description, are novel effective tryptase inhibitors. ... | 06/13/2006 |
| 7056936 | Synergistic combination The invention relates to the combined administration of PDE inhibitors and β2 adrenoceptor agonists for the treatment of respiratory tract disorders. ... | 06/06/2006 |
| 7053176 | Combination of C1-INH and lung surfactant for the treatment of respiratory disorders Pharmaceutical composition for the treatment of infant respiratory distress syndrome and acute lung injury (including adult respiratory distress syndrome) which contains C1 esterase inhibitor (C1-INH) and lung surfactant which comprises a lung surfactant protein. | 05/30/2006 |
| 7041313 | Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release c... | 05/09/2006 |
| 7034178 | Process for the production of 3-phenylisoserine This invention is drawn to a process for the production of (R,R)-phenylisoserine or a 1–4C-alkyl ester thereof. ... | 04/25/2006 |
| 7022696 | Piperazino-derivatives and their use as PDE4 inhibitor The compounds of formula I in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effective PDE4 inhibitors. ... | 04/04/2006 |
| 7022671 | Surfactant protein C esters Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described. ... | 04/04/2006 |
| 6998410 | Compositions Novel compositions for the treatment of IRDS and ARDS are indicated which contain N-(3,5-dichloro-pyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxybenzamide and/or its pharmacologically tolerable salts and lung surfactant. ... | 02/14/2006 |
| 6988619 | Medicinal product package for eradication therapy The object of the present invention is to provide a medicinal product package which is suitable for microbe eradication therapy and with which the patient's compliance is increased and thus the result of therapy is improved. ... | 01/24/2006 |
| 6982075 | Use of pulmonary surfactant The invention describes the novel use of pulmonary surfactant preparations in the artificial respiration of patents with toxic oxygen concentrations. ... | 01/03/2006 |
| 6962941 | Tryptase inhibitors The compounds of formula I in which M, B1, B2, R1, R2, R6, R7, K1 and K2 have the meanings as indicated in the description are novel active tryptase inhibitors. ... | 11/08/2005 |
| 6960588 | Tryptase inhibitors Compounds of formula (I) in which M, B1, B2, B3, B4, B5, B6, A1, A2, A3, A4, A5, A6, K1 and K2 have the meanings as indicated in the description, are novel effective tryptase inhibitors. ... | 11/01/2005 |
| 6953853 | Phthalazinone-piperidino-derivatives as PDE4 inhibitors The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors ... | 10/11/2005 |
