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Assignee: Alkermes, Inc.


Location: Waltham, MA
No. of patents: 6

NumberTitleIssue Date
7919499Naltrexone long acting formulations and methods of use
The inventions described herein arose from unexpected discoveries made during clinical trials with a long acting formulation of naltrexone. As such, the invention includes a method for treating an individual in need of naltrexone comprising the step of parenterally ...
04/05/2011
7879358Pulmonary delivery for levodopa
In one aspect, the invention is related to a method of treating a patient with Parkinson's disease, the method including administering to the respiratory tract of the patient particles that include more than about 90 weight percent (wt %) of levodopa. The particles ...
02/01/2011
7875310Residual solvent extraction method and microparticles produced thereby
Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and ...
01/25/2011
7807200Formulations for spray-drying large porous particles
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a solvent such as an aqueous-organic solvent. The colloidal solution can al...
10/05/2010
7754242Inhalable sustained therapeutic formulations
The present invention is based, in part, on the unexpected discovery that particles for pulmonary delivery of a therapeutic, prophylactic or diagnostic agent that comprise a phospholipid and a sufficient amount of leucine can produce sustained effect of the agent. S...
07/13/2010
7678364Particles for inhalation having sustained release properties
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to particles suitable for use in the method. In particular, the invention rel...
03/16/2010
 
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