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Assignee: Aldrich Chemical Company, Inc.


Location: Milwaukee, WI
No. of patents: 25

NumberTitleIssue Date
6008414Dioxane-monochloroborane and dioxane-dichloroborane
Highly reactive hydroborating agents dioxane-monochloroborane and dioxane-dichloroborane are provided. Also provided by this invention are methods for producing dioxane-monochloroborane, dioxane-dichloroborane and methods for hydroborating olefins with th...
12/28/1999
5567849Borane-sulfide hydroboration agents
A borane-sulfide represented by the formula BH3.SR1 R2 wherein B is boron, H is hydrogen, R1 and R2 each are straight or branched chain alkyl or alkoxy with at least one R being a branched chain when both ...
10/22/1996
5552081Dicyclooctylhaloboranes
A novel class of enolboration reagents represented by the formula R2 BX/R'3 N wherein each R is the same or different alkyl or cycloalkyl, B is boron, X is halo, R' is lower alkyl and/indicates that R2 BX is preferably employed...
09/03/1996
5543569Borane-N,N-dialkylaniline hydroboration agents
Borane-N,N-dialkylanilines represented by the formula H3 B. C6 H5 NRR' wherein N is nitrogen, R is isobutyl or isopropyl and R' is straight or branched chain lower alkyl. The compounds are useful as hydroboration agents and for...
08/06/1996
5504240Borane-hydroxydialkylsulfide borates
Novel borane adducts of hydroxydialkylsulfide borate esters represented by formula ##STR1## wherein R is straight or branched chain alkyl or alkoxy having from 2 to 5 carbon atoms and n is 1 to 3 inclusive. The compound are new hydroboration age...
04/02/1996
5481038Borane-N,N-diisopropylalkylamine hydroboration agents
Borane-N,N-diisopropylalkylamines as represented by the formula: H3 B.NPri2 R wherein Pri is isopropyl, R is branched-chain alkyl or cycloalkyl having 3 to 6 carbon atoms and B is boron are provided. The compounds are ...
01/02/1996
5380940Bis(bicyclo(2.2.2)octyl)haloboranes
A novel class of enolboration reagents represented by the formula R2 BX/R'3 N wherein each R is the same or different alkyl or cycloalkyl, B is boron, X is halo, R' is lower alkyl and / indicates that R2 BX is preferably employ...
01/10/1995
5284976Method of producing primary amines in high yields
A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and R*NH2 in high yields from novel intermediates RBMe2 or R*BMe2 wherein R is an organo group, R* is a chiral...
02/08/1994
5276195Process for producing dimethylorganoboranes
A process for preparing a dimethylorganoborane represented by the formula R*BMe2 wherein R* is a chiral organyl group attached to the boron, B is boron and Me is methyl comprising treating a chiral boronic ester R*B(OR')2 with a meth...
01/04/1994
5220072Process of synthesizing chemically and optically pure B-halodiiso-2-ethylapopinocampheylboranes
A chemically and optically pure B-halodiiso-2-ethylapopinocampheylborane of essentially 100% ee represented by the formula: ##STR1## wherein B is borane and X is halo and a process for preparing....
06/15/1993
5214209Method of producing primary amines in high yields and novel intermediates therefor
A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and R*NH2 in high yields from novel intermediates RBMe2 or R*BMe2 wherein R is an organo group, R* is a chiral...
05/25/1993
5210310Optically active dimethylorganoboranes
A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and R*NH2 in high yields from novel intermediates RBMe2 or R*BMe2 wherein R is an organo group, R* is a chiral...
05/11/1993
5202502Process for producing optically active alcohols
A chemically and optically pure B-halodiiso-2-ethylapopinocampheylborane of essentially 100% ee represented by the formula: ##STR1## wherein B is borane and X is halo, and a process of using such for the production of optically active alcohols....
04/13/1993
5175378Synthesis of optically pure forms of ipsdienol
An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral al...
12/29/1992
5175371Synthesis of optically pure forms of ipsenol
An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral al...
12/29/1992
5159116Chemically and optically pure B-halodiiso-2-ethylapopinocampheylboranes
A chemically and optically pure B-halodiiso-2-ethylapopinocampheylborane of essentially 100% ee represented by ##STR1## wherein B is borane and X is halo....
10/27/1992
5103063Intermediates useful for the chiral isoprenylation of aldehydes
An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral al...
04/07/1992
5087700Method of producing primary amines in high yields
A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and R*NH2 in high yields from novel intermediates RBMe2 or R*BMe2 wherein R is an organo group, R* is a chiral...
02/11/1992
5068432Process for producing optically pure 2-phenoxyphenylalkylamines
A process for producing the optically pure (+)- or (-) isomer of a phenyl- or substituted- phenylalkanolamine compounds having pharmacologic activity without the need for resolution processes and novel intermediates useful in the process including optical...
11/26/1991
5043479Chemically and optically pure diisopinocampheylhaloboranes
Novel chemically pure diisopinocampheylhaloboranes of essentially 100% ee, represented by the formula Ipc2 BX wherein Ipc is isopinocampheyl and X is halo....
08/27/1991
4978794Novel ଲ-(2-alkenyl)bis(2-isocaranyl)boranes
2-Alkenylbis(2-isocaranyl)boranes represented by the formula: ##STR1## wherein R is 2-alkenyl. The compounds undergo asymmetric 2-alkenylboration with a variety of aldehydes and afford the corresponding alcohols in 94-99% ee....
12/18/1990
4918242Novel optically 1,3-phenoxypropylhalides
A process for producing the optically pure (+)- or (-)-isomer of a phenyl- or substituted-phenylalkanolamine compounds having pharmacologic activity without the need for resolution processes and novel intermediates useful in the process including opticall...
04/17/1990
4918246Process for preparing optically active haloalcohols
A process for producing the optically pure (+)- or (-) isomer of a phenyl- or substituted- phenylalkanolamine compounds having pharmacologic activity without the need for resolution processes and novel intermediates useful in the process including optical...
04/17/1990
4918207Novel optically active halo-substituted tetrahydrofurans
A process for producing the optically pure (+)- or (-) isomer of a pheynl- or substituted- phenylalkanolamine compounds having pharmacologic activity without the need for resolution processes and novel intermediates useful in the process including optical...
04/17/1990
4918229Method of producing primary amines in high yields and novel intermediates therefor
A novel process for producing hindered and unhindered primary amines represented by the formula RNH2 and R*NH2 in high yields from novel intermediates RBMe2 or R*BMBe2 wherein R is an organo group, R* is a chira...
04/17/1990
 
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