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| Number | Title | Issue Date |
| 6863073 | Laminar cribosa puncture device, methods related to use of such a device and methods for treating central retinal vein occulsions Featured is a device for puncturing tissue of a body, such as the lamina cribosa and methods for treating a CVRO with such a puncturing device. The puncturing device includes a puncture member being generally configured and arranged to locally disrupt tissue proxima... | 03/08/2005 |
| 6184189 | Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems Stable liquid enzyme compositions containing an ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens... | 02/06/2001 |
| 6146622 | Use of certain anionic amino acid based surfactants to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions Anionic amino acid based surfactants are used to enhance antimicrobial effectiveness in topically administrable pharmaceutical compositions containing at least one active ingredient, a cationic preservative and an anionic polyelectrolyte, such as carboxyv... | 11/14/2000 |
| 5990099 | Angiostatic agents and methods and compositions for controlling ocular hypertension Compositions of angiostatic agents for treating GLC1A glaucoma and methods for their use are disclosed.... | 11/23/1999 |
| 5883108 | Combination therapy for treating glaucoma Methods for treating persons with glaucoma or ocular hypertension with polyamine antagonists and an IOP-lowering compounds are also disclosed.... | 03/16/1999 |
| 5547663 | Absolute molecular weight polymers and methods for their use A process for preparing defined molecular weight polymers, particularly polyquaternary ammonium compounds, is disclosed. As the molecular weights of these compounds can be absolutely defined, rather than defined merely in terms of "number average molecula... | 08/20/1996 |
| 5403841 | Use of carrageenans in topical ophthalmic compositions Topical ophthalmic compositions of carrageenans which are administrable as a drop but which become more viscous or gel upon instillation in the eye are disclosed. Methods for use of the compositions as topical ophthalmic vehicles for pharmaceutically acti... | 04/04/1995 |
| 5320839 | Topical ophthalmic compositions comprising 4-(3-substituted amino-2-hydroxypropoxy)-1,2,5-thiadiazoles and methods for their use Topical ophthalmic compositions comprising certain thiadiazoles are useful in the treatment of glaucoma and ocular hypertension. The thiadiazoles are slightly less potent than timolol; however, they have greatly reduced systemic side effects as compared t... | 06/14/1994 |
| 5048727 | Preassembled unit dose dispenser having a compressible container and a tube prefilled with a unit dose of opthalmic gel. A unit dose dispenser for dispensing a composition includes a compressible, air filled container in communication with an open end of a tube filled with the composition. The opposite end of the tube through which the composition is dispensed is sealed wit... | 09/17/1991 |
| 5030651 | Methods and compositions for controlling, preventing and treating oxidative insult in the eye with transition metal complexes Methods for preventing and treating oxidative insult to the eye by the administration of transition metal complexes are disclosed.... | 07/09/1991 |
| 5019037 | Pneumatic retinopexy injector A pneumatic retinopexy injector includes a syringe to which is communicated a controllable gaseous pressure source. A desired volume of a gaseous substance can be injected by the syringe by utilizing a controller to introduce the pressurized gas to the sy... | 05/28/1991 |
| 4822819 | Use of trimoprostil and derivatives in glaucoma therapy Disclosed is the use of trimoprostil, and its derivatives, such as, 15-acetyl trimoprostil and pharmaceutically acceptable salts and esters thereof in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical composi... | 04/18/1989 |
| 4808239 | Method of cleaning contact lens using compositions containing polyether carboxylic acid surfactant Nontoxic, aqueous, contact lens cleaning compositions containing a weakly anionic surfactant, and optionally also a chelating agent, urea and/or a source of hydrated protons, and methods of chemically removing protein, lipid and calcium deposits from cont... | 02/28/1989 |
| 4792414 | Cleaning agent for optical surfaces Soft and hard contact lenses are freed from deposits by rubbing them with a particulate organic polymer with a carrier, the polymer having a particular size in the range from about one micron to about 600 microns and a Rockwell hardness in the range of fr... | 12/20/1988 |
| 4694022 | Fatty acid salts of betaxolol useful in the treatment of glaucoma Fatty acid salts of betaxolol, a cardioselective beta-blocker, and ophthalmic compositions containing these salts are described. These new salts have an aqueous solubility significantly less than that of betaxolol hydrochloride. This relatively poor aqueo... | 09/15/1987 |
| 4690993 | p-(2-Hydroxy hexafluoroisopropyl) styrene [HFIS] monomer for ophthalmic applications Copolymer compositions are prepared from a novel class of siloxane monomers in combination with hydroxyperfluoroalkylstyrenes, preferably p-(2-hydroxy hexafluoroisopropyl)sytrene [HFIS] monomer for ophthalmic applications.... | 09/01/1987 |
| 4587257 | Control of ocular bleeding using clonidine derivatives A method of controlling anterior segment ocular bleeding is described. The method utilizes various clonidine derivatives (e.g., p-aminoclonidine) as the hemostatic agent.... | 05/06/1986 |
| 4443432 | Ophthmalic irrigating solution An ophthalmic irrigating solution useful for irrigating the human eye contains sodium, potassium, magnesium, calcium, chloride, and bicarbonate ions as well as dextrose and glutathione in proportions consistent with the osmotic stability and continued met... | 04/17/1984 |