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Pneumatic Shoe Lacing Apparatus
This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.
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| Number | Title | Issue Date |
| 8133206 | Safety intravenous catheter assembly A safety intravenous catheter assembly includes a needle, a catheter hub having an axial bore extending through the catheter hub and a notch extending outwardly in the axial bore, a needle cover, and a notch clip connected to the needle cover. The notch clip is sele... | 03/13/2012 |
| 8126267 | Methods and apparatuses for analyzing digital images to automatically select regions of interest thereof Computer-implemented image processing methods and apparatuses are presented for automatically selecting regions of interest within an image represented by pixel intensity values. A first pixel box is employed in progressively scanning and evaluating the image. If pi... | 02/28/2012 |
| 8067545 | Isolated antibodies against biologically active leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 11/29/2011 |
| 8043345 | Device and method for correcting a spinal deformity A method for correcting a spinal deformity is provided. A spinal implant for correcting a spinal deformity includes a multipoint connector that connects to at least one vertebra of a spine at a plurality of locations and a force directing device that applies a force... | 10/25/2011 |
| 8022189 | Isolated antibodies against biologically active leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 09/20/2011 |
| 8016860 | Device and method for correcting a spinal deformity A device and method for correcting a spinal deformity are provided. A spinal implant for correcting a spinal deformity includes a multipoint connector that connects to at least one vertebra of a spine at a plurality of locations and a force directing device that app... | 09/13/2011 |
| 8007784 | Antigenic modulation of cells The present invention is directed to a non-immunogenic cellular composition comprising: a cell having a cell surface and antigenic determinants on the cell surface; an optional linker molecule covalently attached to the cell surface; and a hydrophilic, biocompatible... | 08/30/2011 |
| 8002801 | Adjustable spinal implant device and method A spine implant, in particular a stabilization or distraction device, is provided with an adjustable length. The implant has first and second portions for coupling to a first bony portion of a first vertebra and a second bony portion of a second vertebra, respective... | 08/23/2011 |
| 7964701 | Alpha-fetoprotein peptides The invention relates to compounds that include peptides that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwa... | 06/21/2011 |
| 7943577 | Alpha-fetoprotein peptides and uses thereof Therapeutic compounds which are cell proliferation modulators, preferably inhibitors. These modulators contain amino acid structures that are arranged as a hydrophilic analog of an alpha-fetoprotein. The modulator may be a peptide itself, e.g., an octapeptide like t... | 05/17/2011 |
| 7901936 | Method for stimulating self-renewal of neural stem cells and enhancing neurogenesis The present invention provides a mechanism for obtaining an almost unlimited source of stem cells. A method for the expansion of a population of stem cells that retain their developmental capacity comprises co-culture of a stem cell population with a trophic support... | 03/08/2011 |
| 7790683 | Leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 09/07/2010 |
| 7786265 | Isolated antibodies against biologically active leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 08/31/2010 |
| 7658753 | Device and method for correcting a spinal deformity A device and method for correcting a spinal deformity are provided. A spinal implant for correcting a spinal deformity includes a multipoint connector that connects to at least one vertebra of a spine at a plurality of locations and a force directing device that app... | 02/09/2010 |
| 7611526 | Spinous process reinforcement device and method A method and device for reinforcing a spinous process is provided. Also provided are devices and method for attaching devices thereto. ... | 11/03/2009 |
| 7598342 | Alpha-fetoprotein peptides and uses thereof The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by ... | 10/06/2009 |
| 7569033 | Safety intravenous catheter assembly A safety intravenous catheter assembly includes a needle, a catheter hub having an axial bore extending through the catheter hub and a notch extending outwardly in the axial bore, a needle cover, and a notch clip connected to the needle cover. The notch clip is sele... | 08/04/2009 |
| 7405077 | Sperm protein 17 for the diagnosis and treatment of cancer The results herein identify Sp17 as a novel cancer-testis antigen in multiple myeloma. Sp17 recombinant protein was generated from E. coli. A CD8 predominant CTL line was generated that was able to lyse autologous targets in a Sp17-dependent HLA class I-restr... | 07/29/2008 |
| 7208572 | Leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 04/24/2007 |
| 7186694 | Leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 03/06/2007 |
| 6828102 | Plasmids and methods for monitoring endonuclease digestion efficiency A method is disclosed herein for monitoring the efficiency of an endonuclease digestion using a plasmid specifically designed for that purpose. The plasmid of the present invention comprises at least two polylinker regions containing a plurality of unique restrictio... | 12/07/2004 |
| 6780871 | Methods and compositions for treating addiction disorders A method for treating an addiction disorder (such as an addiction to or dependency on stimulants, nicotine, morphine, heroin, other opiates, amphetamines, cocaine, and/or alcohol) in a patient is disclosed. The method includes administering to the patient a first α... | 08/24/2004 |
| 6699465 | Covalent attachment of polymer to cell to prevent virus bonding to receptor A chemo-physiological structure and method for forming the chemo-physiological structure. In a first embodiment, a cell of an animal is provided. The cell has a membrane surface and a viral receptor coupled to the membrane surface. A linker molecule havin... | 03/02/2004 |
| 6695814 | Safety intravenous catheter assembly and method for use with a needle A safety intravenous catheter assembly and method for use with a needle in one embodiment includes a catheter hub and a needle cover attachable to and releasably lockable with the catheter hub when the needle extends through the needle cover. A stop assem... | 02/24/2004 |
| 6689102 | Safety intravenous catheter assembly A safety intravenous catheter assembly includes a catheter hub, a needle cover attachable to and releasably lockable with the catheter hub, and a needle which extends through and is withdrawn into the needle cover. In one embodiment, the safety intravenou... | 02/10/2004 |
| 6555656 | Covalent modification of abnormal prion protein A prion-physiological structure and associated method of formation. A provided abnormal prion has a transforming power over a normal prion to convert the abnornal prion into defective prion that mimics the abnormal prion. A linker molecule is then bonded ... | 04/29/2003 |
| 6524586 | Enhancement of oligomeric viral immunogenicity A method and structure for forming a viral-physiological structure. A naked virus having a capsid is provided. A linker molecule having a covalently attached polymer is covalently bonded to the capsid to form a polymer-protected virus. An immunogenicity o... | 02/25/2003 |
| 6322986 | Method for colorectal cancer prognosis and treatment selection A method predicting the outcome, and prognosis and indicating treatment for patients afflicted with colorectal cancer by determining whether the number of copies of HER-2/neu gene in cancer cells from the patient exceeds four by in-situ hybridization. Pat... | 11/27/2001 |
| 6255089 | Constitutively activated serotonin receptors Mutations have been discovered in mammalian G protein-coupled serotonin 5-HT2A and 5-HT2C receptors which render the mutated receptors constitutively active. An alignment methodology based on the highly conserved sixth transmembrane ... | 07/03/2001 |
| 6221047 | Safety intravenous catheter assembly and method for use with a needle A safety intravenous catheter assembly and method for use with a needle is comprised of the following. A catheter hub has an axial bore extending through the catheter hub. A needle cover has a first end of the needle cover insertable in the axial bore and... | 04/24/2001 |
| 6211360 | Ibogamine congeners The present invention is directed to compounds having formula (1), wherein n is from 0 to 8; R1 is CH2 OH, CH(OH)R5, CH2 OR5, CO2 R5, C(O)NH2, C(I)NHR5, C(O)NR | 04/03/2001 |
| 6165502 | Protein-lipid vesicles and autogenous vaccine comprising the same A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is u... | 12/26/2000 |
| 6048531 | Immunogenic composites capable of stimulating production of anti-peptide antibodies, pharmaceutical compositions employing these composites and methods of selectively inducing production of anti-peptide antibodies An essentially pure immunogenic composite capable of selectively inducing antibody production in an animal to a peptide that if administered by itself to the animal without being conjugated to or mixed with additional substance does not stimulate producti... | 04/11/2000 |
| 5994318 | Cochleate delivery vehicles The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advant... | 11/30/1999 |
| 5994071 | Assessment of prostate cancer A method of determining the severity of prostatic cancer includes measuring the level of amplification of the HER-2/neu gene in a sample of prostate tissue by fluorescence in-situ hybridization and comparing the measured level of amplification of the HER-... | 11/30/1999 |
| 5965567 | Method for treating nicotine addiction The present invention relates to methods for treating nicotine addiction. The method involves administering to the patient an effective amount of a compound having the formula: ##STR1## wherein R1 is selected from the group consisting of h... | 10/12/1999 |
| 5908624 | Antigenic modulation of cells The present invention is directed to a non-immunogenic cellular composition comprising: a cell having a cell surface and antigenic determinants on the cell surface; a linker molecule covalently attached to the cell surface; and a non-immunogenic compound ... | 06/01/1999 |
| 5840707 | Stabilizing and delivery means of biological molecules The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advant... | 11/24/1998 |
| 5837716 | Analgesic heterocyclic compounds The present invention discloses that compounds having the formula: ##STR1## wherein Z represents the atoms necessary to complete a five-membered or six-membered heterocyclic ring; D is a 1-piperid-4-yl moiety, a --Q--NH-- moiety, or a --Q--S-- moiety; Q i... | 11/17/1998 |
| 5834015 | Protein-lipid vesicles and autogenous vaccine comprising the same A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is u... | 11/10/1998 |
