Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Number | Title | Issue Date |
| 6573282 | Peripherally active anti-hyperalgesic opiates Compositions and methods using the compositions for treatment of peripheral hyperalgesia are provided. The compositions contain an anti-hyperalgesia effective amount of one or more compounds that directly or indirectly interact with peripheral opiate rece... | 06/03/2003 |
| 6353004 | Peripherally acting anti-pruritic opiates Anti-pruritic compositions and methods of using the compositions for the prevention or treatment of pruritus comprising: ##STR1## wherein: R, R2, R3, R4, R7, Ar1 and Ar2 are as defined in t... | 03/05/2002 |
| 6303611 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formula having the structure: ##STR1## wherein R1, R2, and X Y, Z, Ar and n are as describe... | 10/16/2001 |
| 6190691 | Methods for treating inflammatory conditions The present invention provides a number of screening methods for evaluating compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a porti... | 02/20/2001 |
| 6180623 | Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and methods of using them as analgesics and anti-pruritic agents are provided. The compounds of formula IV have the structure: ##STR1## wherein X9 ; R1, R | 01/30/2001 |
| 6057323 | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compound of formula I, having the structure: ##STR1## wherein R1, R2 ... | 05/02/2000 |
| 6054445 | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritis therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compound of formulae IIA, having the structure: ##STR1## wherein R1, R2 | 04/25/2000 |
| 6048860 | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.... | 04/11/2000 |
| 6028063 | Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compounds of formula III having the structure: ##STR1## wherein Ar and X7 ; R | 02/22/2000 |
| 6004964 | Kappa agonist anti-pruritic pharmaceutical formulaitons and method of treating pruritus therewith Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.... | 12/21/1999 |
| 5981513 | Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compounds of formula II having the structure: ##STR1## wherein X4, X5... | 11/09/1999 |
| 5962477 | Screening methods for cytokine inhibitors The present invention provides a number of screening methods for evaluatiing compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a port... | 10/05/1999 |
| 5945443 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compound of formulae IV having the structure: ##STR1## wherein X9 ; R1, R2, R3... | 08/31/1999 |
| 5888494 | Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic and pruritic conditions therewith Topical film-forming compositions for the prevention and treatment of prutitus containing an opiate that is substantially devoid of central nervous system effects.... | 03/30/1999 |
| 5869521 | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.... | 02/09/1999 |
| 5849762 | Peripherally acting anti-pruritic opiates Anti-pruritic compositions and methods of using the compositions for the prevention or treatment of pruritus comprising: ##STR1## wherein M is ##STR2## wherein: R, R2, R3, R4, R7, Ar1 and Ar... | 12/15/1998 |
| 5811078 | Spray formulations of antihyperalgesic opiates and method of treating topical hyperalgesic conditions therewith Spray formulations of anti-hyperalgesic opiates having a peripheral selectivity of 251 to 1,280 in a solvent mixture of up to 15% w/w alcohol selected from the group consisting of ethyl propyl and isopropyl alcohol and water greater than or equal to 85% w... | 09/22/1998 |
| 5798093 | Spray formulations of antihyperalgesic opiates and method of treating topical hyperalgesic conditions and pruritus therewith Spray formulations of anti-pruritic opiates having a peripheral selectivity of 251 to 1,280 in a solvent mixture of up to 15% w/w alcohol selected from the group consisting of ethyl, propyl and isopropyl alcohol and water greater than or equal to 85% w/w ... | 08/25/1998 |
| 5763445 | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided. The compounds of formular I, II, III and IV have the structure: ##STR1## wherein X, X4 | 06/09/1998 |
| 5760023 | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith Anti-pruritic pharmaceutical formulations containing kappa agonist compounds and methods of prevention or treatment of pruritus in a mammal with the anti-pruritic formulations.... | 06/02/1998 |
| 5744458 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compound of formula II has the structure: ##STR1## wherein X4, X5 ; R1, R2 ; ... | 04/28/1998 |
| 5688955 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formulae I, II, III and IV have the structure: ##STR1## wherein X, X4, X5, X7 | 11/18/1997 |
| 5667773 | Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith Topical anti-hyperalgesic film-forming compositions and methods of using compositions for the treatment of peripheral hyperalgesia comprising: a) a compound of the formula ##STR1## wherein M is ##STR2## wherein: R, R2, R3... | 09/16/1997 |
| 5646151 | Kappa agonist compounds and pharmaceutical formulations thereof Compounds, compositions and method of treating hyperalgesia comprising a compound of formula I, II, III and IV as defined in the specification.... | 07/08/1997 |