Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 5641630 | Method and kit for performing nucleic acid hybridization assays A method and a kit for the isolation and quantitative detection of a selected target nucleic acid sequence from solution employing two probes. A first probe is complementary to one portion of the target and is covalently attached to a first complexing age... | 06/24/1997 |
| 5273882 | Method and kit for performing nucleic acid hybridization assays A method and a kit for the isolation and quantitative detection of a selected target nucleic acid sequence from solution employing two probes. A first probe is complementary to one portion of the target and is covalently attached to a first complexing age... | 12/28/1993 |
| 5198289 | Ultrasonically cut fibrous material An article is disclosed which comprises fibrous material which has been chemically modified such that the material's cutability using ultrasonic energy becomes facile and the material can be cut into a predetermined shape using ultrasonic energy. The arti... | 03/30/1993 |
| 5198368 | Methods for performing a solid-phase immunoassay A method for performing a microparticle diagnostic assay in a device having a shallow sample well for receiving a sample and reagents for forming a reaction mixture, a read well positioned adjacent to said sample well and separated from said sample well b... | 03/30/1993 |
| 5149505 | Diagnostic testing device A diagnostic testing device is disclosed. The testing device includes a base member and a cover member which defines an opening for the reception of a liquid specimen. A distribution wheel delivers portions of the specimen to antibiotic units which are ci... | 09/22/1992 |
| 5149622 | Solid phase analytical device and method for using same A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of sub... | 09/22/1992 |
| 5134359 | Apparatus for measuring electrolytes including optical measurements Apparatus for measuring electrolyte concentrations in fluid samples. The apparatus includes an ion selective electrode capable of generating a voltage differential having a magnitude related to the concentration of the corresponding electrolyte in the sam... | 07/28/1992 |
| 5134675 | Beveled angle fiber optic connector A fiber optic connector in which first and second optical fibers are aligned at a fiber interface of the connector. The first optical fiber has a beveled angle end face, and the second optical fiber has a complementary beveled angle end face. Abutting con... | 07/28/1992 |
| 5066426 | Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure and to... | 11/19/1991 |
| 5057302 | Bifunctional chelating agents The present invention provides bifunctional chelating agents comprising a unique substrate reactive moiety incorporated into a carboxymethyl arm of a polyaminopolycarboxylate chelating framework capable of forming stable complexes with metal ions.... | 10/15/1991 |
| 5013645 | Immunological methods and materials for detection of tumor associated antigens Disclosed are immunological methods and materials for detection of antigens associated with breast or prostate cancer disease states. Presently preferred antibody preparations (e.g., PR92 monoclonal antibodies produced by hybridoma cell line ATCC HB 9390)... | 05/07/1991 |
| 4939264 | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies The present invention is directed to a fluorescence polarization assay for opiate alkaloids and their metabolites, to the various components needed for preparing and carrying out such an assay and to methods of making these components. Specifically, trace... | 07/03/1990 |
| 4936963 | Polycationic buffers and method for gel electrophoresis of nucleic acids The present invention provides for polycationic buffers for the gel electrophoresis of and methods for obtaining improved separation and resolution of nucleic acids. In particular, the invention provides for a buffer consisting essentially of histidine fo... | 06/26/1990 |
| 4933147 | Unitized reagent containment system for clinical analyzer Improvements in apparatus for performing an assay to determine the presence or amount of a substance in a test sample, which apparatus comprises means for dispensing one or more reagents from containment means therefor into a reaction vessel and means for... | 06/12/1990 |
| 4931404 | Method and device for ketone measurement The present invention relates to methods and materials for the detection of ketone and aldehyde analytes in fluid samples by means of reacting analyte containing samples with a matrix comprising a hydrazine compound coupled to an H+ ion exchang... | 06/05/1990 |
| 4912208 | Fluorophores for encapsulation into liposomes The present invention provides novel fluorescein derivative compounds having fluorescence spectrum and quantum yield characteristics similar to those of fluorescein. The compounds are readily synthesized and purified and are readily soluble in water at se... | 03/27/1990 |
| 4902630 | Fluorescence polarization immunoassy and reagents for measurement of c-reactive protein This disclosure relates to a fluorescence polarization immunoassay method for determining C-reactive protein in liquids, especially in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. This disclosure also relates to novel r... | 02/20/1990 |
| 4897244 | Apparatus and methods for analyzing fluids Apparatus and methods for analyzing fluid such as blood serum. A probe used for transferring some of the fluid to a testing station causes a change in circuit capacitance when the probe contacts the fluid. This change in capacitance causes production of a... | 01/30/1990 |
| 4891311 | Stabilized enzyme conjugate composition An enzyme conjugate composition comprising an enzyme conjugate, a calcium salt and a polyethylene glycol is disclosed. The enzyme conjugate composition is effectively stabilized by the presence of the calcium salt and the polyethylene glycol.... | 01/02/1990 |
| 4889612 | Ion-selective electrode having a non-metal sensing element An ion-selective electrode having an electrically insulating substrate with a substantially planar first surface, and having a non-metallic conductor for sensing a potential affixed to the first surface beneath an ion-sensitive membrane. An electrically i... | 12/26/1989 |
| 4883763 | Sample processor card for centrifuge A sample processor card for use with a centrifuge in which the direction of centrifugal force can be altered at will, wherein the card includes a supply of chemical reagent and inlet means for supplying a chemical sample to the card. The sample is advance... | 11/28/1989 |
| 4874748 | Cloning vectors for streptomyces and use thereof in macrolide antibiotic production DNA cloning shuttle vectors, including a cosmid shuttle vector, for E. coli and Streptomyces are disclosed. Specifically, disclosed shuttle vectors pAL7002 (NRRL B-18055) and pNJl (NRRL B-18054) contain an E. coli origin of replication, Streptomyces repli... | 10/17/1989 |
| 4873035 | Preparation of sized populations of liposomes The present invention provides novel methods for generating aqueous liquid encapsulating multi-lamellar lipid vesicles (liposomes) wherein one or more lipids, or lipid conjugates, and an aqueous liquid to be encapsulated, are agitated in a vessel in the p... | 10/10/1989 |
| 4868132 | Fluorescence polarization immunoassay for amphetamine/methamphetamine This disclosure relates to a method and reagents for determining amphetamine and methamphetamine in a biological fluid such as urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure for determining the presence ... | 09/19/1989 |
| 4859420 | Heating system for rotating members A heating system for heating a rapidly rotating article, including a strobe capable of emitting radiant energy and positioned to radiate energy onto the article, a light source positioned to illuminate a temperature-sensing means on the article, a light d... | 08/22/1989 |
| 4855110 | Sample ring for clinical analyzer network A sample containment apparatus for use in an automated analyzer network is disclosed. The sample containment apparatus comprises a ring and a plurality of sample containers attached or mounted thereto. Each sample container has the capacity to contain an ... | 08/08/1989 |
| 4849177 | Reagent pack and carousel A multiple dose reagent pack and corresponding carousel for an automated analyzer are disclosed. The reagent pack contains a plurality of vial-receiving wells which receive and hold a plurality of reagent-containing vials to form a unitary reagent pack. T... | 07/18/1989 |
| 4821558 | Ultrasonic detector An ultrasonic detector for detecting air in a fluid. A fluid pumping cassette includes an elastomeric member that defines three sides of a fluid passageway, a base of the cassette defining the other side. Resilient lobes on the elastomeric member extend o... | 04/18/1989 |
| 4814282 | Centrifuge for two-dimensional centrifugation Method and apparatus for generating centrifugal forces, including a plate rotatable about an axis, and at least one holding means mounted on the plate for rotation therewith, the holding means being adapted to receive an article to be subjected to centrif... | 03/21/1989 |
| 4810655 | Method for measuring oxygen concentration Methods and compositions are described for measuring oxygen concentration, particularly for monitoring oxygen in the blood with a fiber optic catheter. Oxygen concentration is determined by observing quenching of the emission from a luminescent (phosphore... | 03/07/1989 |
| 4800167 | Reagent and process for the determination of hemoglobin in blood A reagent system for determing the hemoglobin content of whole blood comprising an aqueous solution of polyvinylpyrrolidone of molecular weight from about 10,000 to about 360,000 at a pH greater than about 8.0 to denature hemoglobin in whole blood. A meth... | 01/24/1989 |
| 4786279 | Container for mixture of materials A container having two compartments for keeping two materials in separated relation. When it is desired that the two materials be intermixed, an actuator carrying a pair of piercing pins is inserted into ports of the compartments until membranes blocking ... | 11/22/1988 |
| 4784259 | Container construction with vaned extractor A flexible diluent container has a vaned port plug which enhances or modifies the mechanical interlock with a stopper of an additive vial in a drug delivery system. The additive vial is screwed into the port of the diluent container with the recess of the... | 11/15/1988 |
| 4784658 | Container construction with helical threaded extractor A flexible diluent container has a helical threaded port plug which enhances or modifies the mechanical interlock with a stopper of an additive vial in a drug delivery system. The additive vial is screwed into the port of the diluent container with the re... | 11/15/1988 |
| 4781679 | Container system with integral second substance storing and dispensing means The invention is an integral container system designed for separately storing a liquid, such as a diluent, and a second substance, such as a medicament, and subsequently adding the second substance to the liquid in a simple and sterile operation. In one e... | 11/01/1988 |
| 4777253 | Process for preparation of racemate and optically active ofloxacin and related derivatives A process for producing racemic or optically active compounds of the formula: ##STR1## wherein R1 is hydrogen, C1 to C6 alkyl or benzyl; and Z is amino or substituted amino. Also disclosed are intermediates useful in ... | 10/11/1988 |
| 4776832 | Centrifuge having multiple induction motors for rotating objects about a second axis An improved centrifuge, including a main wheel for rotating objects to be subjected to centrifugal force about a main axis of rotation, is disclosed. Such objects are simultaneously rotated about a second axis of rotation from a first to a second position... | 10/11/1988 |
| 4774246 | Quinoline antibacterial compounds Quinoline compounds having the formula: ##STR1## wherein R is a phenyl or substituted phenyl group or an aromatic heterocyclic group, R1 is a hydrogen or a carboxy-protecting group and Z is an amine group or an aliphatic heterocyclic group... | 09/27/1988 |
| 4767762 | Tricyclic quinoline and naphthyride antibacterials This invention relates to novel isoxazolo-naphthyridine, isoxazolo-quinoline, isothiazolo-naphthyridine, and isothiazolo-quinoline, derivatives having antibacterial properties.... | 08/30/1988 |
| 4762845 | 7-(3-Substituted imino-1-pyrrolidinyl)-quinolone-3-carboxylic acids New 7-substituted 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids or esters having a substituted or unsubstituted phenyl radical, an aromatic heterocyclic radical, an alkyl or cycloalkyl radical in the 1-position are antibacterial agents.... | 08/09/1988 |
