Assignee: Abbott GmbH & Co. KG

Location: Wiesbaden, DE
No. of patents: 74

Number	Title	Issue Date
8183237	Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HTreceptor The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for trea...	05/22/2012
8163698	Dolastatin 15 derivatives Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L (I), and acid salts thereof, wherein A, B, D, E, F, G and K are α-amino acid residues, and s and ...	04/24/2012
8129389	Substituted oxindole derivatives, medicaments containing the latter and use thereof The invention relates to novel oxindole derivatives of general formula (I), in which the substituents A, B, R1, R2 and R3 are defined as cited in claim 1, to medicaments containing said derivatives and to the use of the latter...	03/06/2012
8114875	Substituted N-heterocyclic compounds and their use as dopamine Dreceptor ligands The invention relates to substituted N-heterocyclic compounds of general formula (I.A) and to the tautomers of the compounds the physiologically acceptable salts of the compounds and the physiologically acceptable salts of ...	02/14/2012
8101754	Triazole compounds suitable for treating disorders that respond to modulation of the dopamine Dreceptor The invention relates to compounds of the formula I: wherein n is 1 or 2, Ar is a C-bound 1,2,4-triazol radical which carries a radical R1 on the remaining carbon atom and a radical R	01/24/2012
8076326	N-phenyl- (piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenl-(piperazine or homopiperazine) compounds suitable for treating disorders that respond to modulation of the serotonin 5-HTreceptor The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable th...	12/13/2011
8044079	Substituted oxindole derivatives, medicaments containing said derivatives and use thereof The invention relates to novel oxindole derivative of general formula (I), wherein the substituents R1, R2, A, B, and Y are defined as in Claim 1. The invention further relates to medicaments containing said derivatives, and use thereof ...	10/25/2011
8044069	Compounds as calcium channel blockers The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein Ar1, Ar2, L1, L2, n, R1, R4, X and Y are as defined...	10/25/2011
8034381	Method for producing ultrafine submicronic suspensions The invention concerns a method for producing ultrafine suspensions, characterized in that a substance in the form of a solid product at 20° C. is dissolved in a solvent, in that the solvent is very rapidly substantially drawn from said solution, in that the powder...	10/11/2011
8008488	Pyrimidin-2-one compounds and their use as dopamine Dreceptor ligands The invention relates to pyrimidin 2-one compounds of general formula (I), in addition to the derivatives and tautomers of (I) and the physiologically acceptable salts of said compounds. In said formula, A represents linear or branched C3-C6 al...	08/30/2011
7994160	Pyridazine compounds as glycogen synthase kinase 3 inhibitors Disclosed are pyridazine compounds of the formula I which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds:	08/09/2011
D641864	Tablet	07/19/2011
D641863	Tablet	07/19/2011
RE42477	Carboxylic acid derivatives, their preparation and use Carboxylic acid derivatives where R-R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. ...	06/21/2011
7960386	Pyridin-2-one compounds and their use as modulators of the dopamine D3 receptor The invention relates to pyridin-2-one compounds of general formula (I) in which A represents a 4- to 6-membered hydrocarbon chain that can have 1 or 2 methyl groups as substituents, wherein 1 or 2 carbon atoms...	06/14/2011
RE42462	Carboxylic acid derivatives, their preparation and use Carboxylic acid derivatives where R-R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. ...	06/14/2011
7956093	Substituted amides, their preparation and use An amide of the formula I and its tautomeric forms, possible enantiomeric and diastereomeric forms, E and Z forms, and possible physiologically tolerated salts. ...	06/07/2011
7951807	Substituted oxindol derivatives and medicaments containing the same The present invention relates to novel oxindole derivatives of the general formula (I), wherein the substituents A, B, R1, R2 and R3 are as defined in Claim 1, and medicaments contain...	05/31/2011
7902379	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5 R6 and R7 are defined according to claim 1, and to medicaments containing them for t...	03/08/2011
7883704	Methods for inhibiting the activity of the P40 subunit of human IL-12 Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12 ) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention ca...	02/08/2011
7846477	Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic ...	12/07/2010
7863445	Carboxylic acid derivatives, their preparation and use Carboxylic acid derivatives where R-R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. ...	01/04/2011
7851463	Heterocyclic compounds suitable for treating disorders that respond to modulation of the dopamine Dreceptor The invention relates to compounds of the formula (I). The invention also relates to the use of a compound of the formula I or a pharmaceutically acceptable salt thereof for preparing a pharmaceutical composition for the treatment of a medical disorder susceptible t...	12/14/2010
7834048	Azabicycloheptyl compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor The present invention relates to a compound of the formula (I) wherein R1 is H, C1-C6-alkyl which may be substituted by C3-C6-cycloalkyl, fluorinated C	11/16/2010
7833547	Ibuprofen and narcotic analgesic compositions Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler se...	11/16/2010
7807779	Antineoplastic peptides The present invention provides antineoplastic peptides of formula I, R1R2N—CHX—CO—A—B-D-E-(G)s-K wherein R1, R2, X, A, B, D, E, G, K and s have the meanings stated in the description....	10/05/2010
7803834	Substituted oxindole derivatives, drugs containing said derivatives and the use thereof The invention relates to novel oxindol derivative of general formula (I), wherein substituents R1, R2, A, B and Y are such as defined in a claim 1. Drugs containing said derivatives and the use thereof for preventing and/or treating vass...	09/28/2010
7799809	Carboxamide compounds and their use as calpain inhibitors The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carbo...	09/21/2010
7790727	Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for trea...	09/07/2010
7786105	Pyrimidine compounds and use thereof The invention relates to pyrimidine compounds of general formula (I), and to the use of these compounds of general formula (I) and of the physiologically compatible acid addition salts of compounds (I) for producing a pharmaceutical agent for treating diseases, whic...	08/31/2010
7759397	6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine Dreceptor The present invention relates to 6-amino(aza)indane compound of the formula (I) Wherein Ar is phenyl or an aromatic 5- or 6-membered C-bound heteroaromatic radical, wherein Ar may carry 1 radical Ra and wherein Ar may also carry I or 2 radicals Rb	07/20/2010
7728012	Carboxamide compounds and their use as calpain inhibitors The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carbo...	06/01/2010
7662786	Dolastatin 15 derivatives Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, A-B-D-E-F-(G)r-(K)s-L (I), and acid salts thereof, wherein A, B, D, E, F, G and K are α-amino acid residues, and s and...	02/16/2010
7601730	Carboxylic acid derivatives, their preparation and use Carboxylic acid derivatives where R—R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. ...	10/13/2009
7582647	Carboxylic acid derivatives, their preparation and use Carboxylic acid derivatives where R—R6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases. ...	09/01/2009
7491729	3-Substituted 3,4-dihydro-thieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof 3-Substituted 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof. The invention relates to 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives which are substituted in position 3 by 5-membered heteroaryl which may be fused to an aryl or ...	02/17/2009
7465744	Triazole compounds and the therapeutic use thereof The invention relates to triazole compounds of general formula (I), wherein A, B, R1, R2, R3 and R4 have the meaning cited in claim 1. The invention also relates to a pharmaceutical agent containing at least one compound o...	12/16/2008
7369946	Method of identifying inhibitors of Tie-2 The present invention relates to polypeptides which comprise the ligand binding domain of Tie-2, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Tie-2. The inventi...	05/06/2008
7332497	Pyrazolopyrimidines as therapeutic agents The present invention provides compounds of Formula I, including pharmaceutically acceptable salts and/or prodrugs thereof, where G, Ra, R2, and R3 are defined as described herein...	02/19/2008
7320979	N-[(piperazinyl)hetaryl]arylsulfonamide compounds The invention relates to N-[(piperazinyl)hetaryl]arylsulfonamide compounds of the general formula I in which Q is a bivalent, 6-membered heteroaromatic radical which possesses 1 or 2 N atoms as ring ...	01/22/2008

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Assignee: Abbott GmbH & Co. KG