...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 8109994 | Biodegradable drug delivery material for stent A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is ... | 02/07/2012 |
| 8100855 | Methods and devices for eluting agents to a vessel Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment... | 01/24/2012 |
| 8100837 | Superelastic guidewire with locally altered properties A guidewire formed at least in part of a superelastic member with a section having one or more altered properties including physical and mechanical properties. Preferably, the section of altered property has reduced superelasticity with respect to the remainder of t... | 01/24/2012 |
| 8076529 | Expandable member formed of a fibrous matrix for intraluminal drug delivery An intraluminal catheter device having an expandable member formed of a matrix of fiber elements with a therapeutic agent incorporated therein. The therapeutic agent can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a ... | 12/13/2011 |
| 8070719 | Low compliant catheter tubing Balloon catheter comprises a shaft having a proximal end, a distal end, and an inflation lumen extending therein, and a balloon on the shaft which has an interior in fluid communication with the inflation lumen. The balloon is formed of a blend of polymeric material... | 12/06/2011 |
| 8052638 | Robust multi-layer balloon A multilayer balloon catheter is formed to have an inner layer and an outer layer, where the outer layer is adapted to resist shredding and premature rupture. The outer layer is formed of a material having a glass transition temperature that is lower than the transi... | 11/08/2011 |
| 8049061 | Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axi... | 11/01/2011 |
| 8048441 | Nanobead releasing medical devices Medical devices comprising nanobeads encapsulating one or more bioactive agents and methods of use thereof are provided. ... | 11/01/2011 |
| 8029558 | Stent and catheter assembly and method for treating bifurcations An improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The stent includes rings aligned along a common longitudinal axis and connected by links, where the stent has one or more portal... | 10/04/2011 |
| 8017237 | Nanoshells on polymers Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. ... | 09/13/2011 |
| 7972356 | Flexible and conformable embolic filtering devices A self-expanding cage for use in conjunction with an embolic filtering device includes one or more circumferential members adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. At least one proximal strut and at least... | 07/05/2011 |
| 7959999 | Hybrid stent and method of making A stent is formed by encasing or encapsulating metallic rings in an inner polymeric layer and an outer polymeric layer. At least one polymer link connects adjacent metallic rings. The stent is drug loaded with one or more therapeutic agent or drug, for example, to r... | 06/14/2011 |
| 7918011 | Method for providing radiopaque nitinol alloys for medical devices A radiopaque nitinol medical device such as a stent for use with or implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element selected from the group of chemical elements... | 04/05/2011 |
| 7906066 | Method of making a balloon catheter shaft having high strength and flexibility A catheter having an elongated shaft with a tubular member which forms at least a portion of the shaft and which is formed of a biaxially oriented thermoplastic polymeric material, and a method of forming the catheter shaft by radially and longitudinally expanding t... | 03/15/2011 |
| 7569655 | Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a... | 08/04/2009 |
| 7549975 | Catheter having a readily bondable multilayer soft tip A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon. ... | 06/23/2009 |
| 7455853 | Medical devices containing rapamycin analogs A medical device comprising a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a co... | 11/25/2008 |
| 7418289 | Markers for interventional devices in magnetic resonant image (MRI) systems Methods and apparatuses for locating a catheter, or other medical international devices are described herein. In one aspect of the invention, an exemplary method includes providing a pressure sensitive device attached to a body of a catheter, providing a resonant ci... | 08/26/2008 |
| 7364657 | Integrated system for on-site cell acquisition, processing, and delivery Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate mononuclear cells, which can then be delivered back near the cardiac tis... | 04/29/2008 |
| 7364567 | Systems and methods for detecting tissue contact and needle penetration depth Systems and methods for determining tissue contact and penetration depth are provided. In one aspect, the system includes a needle and a pressure measurement assembly. The needle, in one exemplary embodiment, includes a first end and a second end with at least one a... | 04/29/2008 |
| 7335227 | Multilayer stent A composite stent having a substrate tube made of stainless steel, a nickel-cobalt-chromium-molybdenum alloy, or chonichrome with at least one metal cladding tube is disclosed. Specifically, the substrate tube is placed within a metal cladding tube made of platinum,... | 02/26/2008 |
| 7335213 | Apparatus and methods for heart valve repair Embodiments of a medical device and methods for percutaneously treating a heart valve. In one embodiment, the medical device has a first cardiac tissue fastener having a first lock, a second cardiac tissue fastener having a second lock, and a chord coupled to the fi... | 02/26/2008 |
| 7331972 | Heart valve chord cutter A medical device and method for percutaneously treating a heart valve. In one embodiment, the medical device includes a catheter having a proximal portion, a distal portion, and a notch formed near the distal portion. A cutting element may be disposed within the dis... | 02/19/2008 |
| 7329223 | Catheter with optical fiber sensor An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a thera... | 02/12/2008 |
| 7326238 | Method and apparatus for treating vulnerable plaque An apparatus and method to treat vulnerable plaque. In one embodiment, the apparatus has a medical device to treat an occlusive plaque, and is also adapted to release a biologically active agent to treat vulnerable plaque located downstream from the occlusive plaque... | 02/05/2008 |
| 7311970 | Medical device having surface modification with superoxide dismutase mimic A medical device comprising a substrate having a plasma polymerized functionality bonded to at least a portion of the substrate. A superoxide dismutase mimic agent having a complimentary functional group to the plasma polymerized functionality is bonded to the porti... | 12/25/2007 |
| 7258753 | Superelastic guiding member An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one... | 08/21/2007 |
| 7250058 | Radiopaque intraluminal stent The present invention includes a radiopaque stent comprising a cylindrical main body. The tubular main body comprises a cobalt chromium alloy that comprises cobalt, chromium and one or more radiopaque materials. ... | 07/31/2007 |
| 7250041 | Retrograde pressure regulated infusion A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the deliv... | 07/31/2007 |
| 7244319 | Superelastic guiding member An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one... | 07/17/2007 |
| 7241257 | Devices and methods to perform minimally invasive surgeries In one embodiment, there is disclosed a device adapted to be used for percutaneous minimally invasive heart surgery including a catheter having a proximal end and a distal end adapted to be fed through a blood vessel, a pump associated with the distal end of the cat... | 07/10/2007 |